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In previous studies in southern Sweden, early use of oral contraceptives has been found to be accompanied by an increased risk of developing premenopausal breast cancer, and the tumors developing in these patients have shown a more aggressive behavior. In the present study, amplification of the proto-oncogenes Her-2/neu (also known as ERBB2) and INT2 was studied in primary tumor specimens from 72
The paper uses an unconventional story format to report on three cases of tourism innovation, using the literary genre of nonsense to also contemplate narrative expression in academic research. Case materials principally derive from open in-depth interviews. The analysis highlights the importance of knowledge in innovation, also illuminating an important relationship to entrepreneurial passion. No
The European Union’s Generalized System of tariff Preferences currently provides preferential access to 176 countries. In 2007 the total value of the preferential imports was €57 billion. The objective of the European Union’s Generalized System of Preferences is to promote development through preferential trade. Thus the countries benefit from various tariff reductions and exceptions depending on
I use Swedish establishment-level panel data to test the hypothesis of Bertola and Rogerson (Eur Econ Rev 41:1147-1171 1997) of a positive relation between the degree of wage compression and job reallocation. Results indicate that the effect of wage compression on job turnover is positive and significant in the manufacturing sector. The wage compression effect is stronger on job destruction than o
Migraine is a common neurological disorder that afflicts up to 15% of the adult population in most countries, with predominance in females. It is characterized by episodic, often disabling headache, photophobia and phonophobia, autonomic symptoms (nausea and vomiting), and in a subgroup an aura in the beginning of the attack. Although still debated, many researchers consider migraine to be a disor
Background: Pancreatic ductal adenocarcinoma is a highly fatal malignancy. The aim was to identify preoperative factors for early mortality in up-front resectable patients following pancreatoduodenectomy (PD) and develop an early mortality risk score. Methods: Patients registered in the Swedish National Registry for Pancreatic and Periampullary Cancer were included. Relevant preoperative factors (
Hypertension in primary hyperparathyroidism (HPT) was previously attributed to hypercalcemia per se or to impaired kidney function. Of 441 consecutive patients operated on for HPT over 24 years, 57% were hypertensive. Preoperative blood pressure remained fairly constant during the study period, despite otherwise markedly changing clinical picture with, latterly, more asymptomatic patients. The pre
Purpose: To search for the tube voltage which results in the highest clinical image quality per effective dose unit for chest and pelvis radiography respectively, using image plates. Methods: Two anthropomorphic phantoms were imaged with several different tube voltages. For the chest phantom, the tube voltage was varied between 70 and 150 kV, and for the pelvis phantom between 50 and 102 kV. The m
Over the years, two strands of thought on Sustainable Development (SD) have emerged, often identified as ecologism and environmentalism, respectively. This paper suggests that there exists a third rhetorically excluded option, namely large-scale industrial expansion into space. Access to raw materials found on the Moon as well as unfiltered solar energy would dramatically increase the stock of res
In this paper, the critical factors behind commercialization of new product development (NPD) are investigated in order to add to our understanding of what drives and hampers the commercialization of new products and services. With the illustration of nine cases of commercialization from three multinational organizations, an initial framework of three categories of factors related to the success o
