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Introduction: The physical activity health paradox refers to the contrasting associations of leisure-time physical activity and occupational physical activity with cardiovascular disease, but whether this applies to Type 2 diabetes risk is unknown. This study aimed to investigate the physical activity health paradox and age-specific Type 2 diabetes. Methods: Working adults (N=5,866) in Denmark age
We aimed to describe the clinical characteristics of families with heritable TP53-related cancer (hTP53rc) syndrome in Sweden with class 4 and 5 germline TP53 variants (gTP53), and to evaluate the genotype-phenotype correlation. These results were also used to evaluate our previously published phenotype prediction model based on TP53 missense variants and their impact on protein conformation. 90 f
At the current time, social robots are poised to enter human society in an unprecedented way. However, robots currentlyare not adept at communicating emotional states, even if humans to a large extent rely on such communication to regulateinteraction. Although facial expressions are difficult for robots to make use of, colored lights are readily available. Currentlythough, there is no consensus on
With simultaneous policy and scholarly attention to the pollution crisis and the climate crisis, there is growing recognition that the two are intimately interconnected through the demand for oil, gas, and coal generated by synthetic materials. Drawing on theoretical resources from international political economy and beyond, we show how petrochemicals sit at the intersection of a number of the pri
Membrane filtration of kraft black liquor (KBL), a side-stream of the pulp and paper industry, is challenged by membrane fouling caused by its multicomponent complexity. The specific contributions of the components found in KBL to the fouling and the characteristics of the fouling layer that they create has not been investigated. Herein, the adsorptive and desorptive behaviours of KBL ultrafiltrat
Background: Previous studies indicate comparably greater improvement in glycaemic control from Paleolithic diet, possibly due to an accompanying greater reduction in body weight, which, in turn, could be due to an accompanying greater reduction in leptin.Aims: To assess in type 2 diabetes the effect of Paleolithic diet on glycaemic control when body weight is kept stable and diets matched for macr
BackgroundCerebral small vessel disease (CSVD) is one of the most important causes of cognitive decline. Only a few previous studies have evaluated lung function measures in relation to brain neuropathological changes, and even less studies on specific lesions and areas that could shed light on mechanisms of CSVD.ObjectiveThe aim was to study the association between lung function and CSVD in the g
BACKGROUND: Male arginine vasopressin 1a receptor knockout mice (V1aR(-/-)) display a phenotype of low triglycerides and high glucose concentrations and high-fat-diet-induced obesity and diabetes. OBJECTIVE: We investigated whether genetic variation of the human arginine vasopressin 1A (AVPR1A) gene is associated with phenotypic features resembling those of the V1aR(-/-) mouse. DESIGN: In a popula
