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A method based on hollow fiber supported liquid membrane extraction coupled with a gas chromatograph equipped with flame ionization detector (GC-FID) was developed for the determination of six short-chain fatty acids including acetic acid, propionic acid, i-butyric acid, n-butyric acid, i-valeric acid and n-valeric acid in serum. Hollow fiber supported liquid membrane extraction was employed for p
Researchers of work-related musculoskeletal disorders are increasingly asked about the evidentiary base for mechanical exposure reductions. Mixed messages can arise from the different disciplinary cultures of evidence, and these mixed messages make different sets of findings incommensurate. Interventions also operate at different levels within workplaces and result in different intensities of mech
Laminins are heterotrimeric glycoproteins of the basement membranes. Laminin 1 (alpha 1, beta 1, gamma 1) is the major laminin expressed during early mouse embryogenesis. To gain access, to the physiological function of laminin alpha 1 chain, we developed a conditionally null allele of its encoding gene (Lama1) using the cre/loxP system. Floxed-allele-carrying mice (Lama1(flox/flox)) display no ov
Collagen type II (CII) is a relevant joint-specific autoantigen in the pathogenesis of rheumatoid arthritis (RA). Whereas the reasons for the breakage of self tolerance to this major cartilage component are still enigmatic, T cell responses to glycosylated CII determinants in RA patients indicate that post-translational modifications play a role. Since the conversion of arginine into citrulline by
Solar mean magnetic field (SMMF) measurements from the Wilcox Solar Observatory and with the SOHO/MDI instrument are described and analyzed. Even though two completely different methods of observation are used, the two data sets obtained show a strong similarity. Using continuous wavelet transforms, SMMF variability is found at a number of temporal scales. Detected SMMF signals with a 1–2 year per
In this work we present a new low-power medium access scheme for sensor-type networks specifically with low traffic intensity. We call the proposed scheme DCW-MAC where ultra-low-power wake-up receivers are combined with optimal duty-cycled listening. First we introduce a framework for the analysis of energy consumption of the studied network type, then we use it to optimize the MAC scheme to achi
The purpose of this thesis is to study conceptions of mental illness in Sweden during the second half of the 19th century. The central aim has been to analyze how mental illness was understood and interpreted in what was a continual interaction between medical professionals and lay people. The relationship between the local community and the asylum influenced the admittance and discharge of patien
As Syria’s anti-authoritarian uprising and subsequent civil war have left the country in ruins, the need for understanding the nation’s complex political and cultural realities remains urgent. The second of a two-volume series, Syria from Reform to Revolt: Culture, Society, and Religion draws together closely observed, critical and historicized analyses, giving vital insights into Syrian society t
In the present work surface thermometry using a method based on the spectroscopy of inorganic luminescent material has been applied in a full-size aircraft jet engine. The technique utilizes laser-induced emission from thermographic phosphors for, non-intrusive, remote temperature diagnostics in combustion applications with high sensitivity and accuracy. In the present application the laser-induce
Popular Abstract in SwedishDenna avhandling studerar relationer mellan film och historia. Tesen som drivs är följande: Film utgör ett i stora delar outnyttjat historiskt källmaterial som alltid säger mer av empiriskt värde om sin produktionskontext än det gör om perioden som skildras. Denna tes bygger vidare på resonemang kring film och historia som genom åren har framlagts av företrädesvis historThe hypothesis put forward in this thesis stipulates that films always say more of empirical value about the time in which they are produced than they do about the periods they depict. The aim is not only to prove that such an idea is valid, but also that it might be transformed into a new and applicable theory in studies of film and history. Here, this is done in contextualized analyses of the pr
Designs for Extremely Large Telescopes (ELTs) are quite well advanced,but the requirements of instruments have had limited impact. Sinceprovision of a suitable environment for instruments is a critical aspectof all telescopes, we outline some well-known and some less-appreciatedchallenges of designing instruments for ELTs. A wide-field spectrometer(WFSPEC) with ~10 arcmin field-of-view, probably w
During the last decade, a new design of schools with fan assisted natural ventilation has been introduced. Experience and knowledge of this type of ventilation system is therefore needed. The objective of the project is to study the technical and physical conditions required to ensure satisfactory ventilation. The whole project includes analyses of the air flows for different combinations of outdo
Recently BRCA1 has been implicated in the regulation of gene expression from the X chromosome. In this study the influence of BRCA1 on expression of X chromosome genes was investigated. Complementary DNA microarrays were used to compare the expression levels of X chromosome genes in 18 BRCA1-associated ovarian cancers to those of the 13 "BRCA1-like" and 14 "BRCA2-like" sporadic tumors (as defined
Transcriptomics analysis revealed that genes involved in hepatic de novo cholesterol synthesis were down-regulated in fed HSL-null mice that had been on high-fat diet (HFD) for 6 months. This finding prompted a further analysis of cholesterol metabolism in HSL-null mice, which was performed in fed and 16-h fasted mice on a normal chow diet (ND) or a HFD regimen. Plasma cholesterol was elevated in
Popular Abstract in Swedish Av pedagogiska skäl har anförts att det finns behov av mer kunskaper om människans tänkande om och förhållningssätt till munhälsa och tandvård. Syftet med denna undersökning var att undersöka och beskriva vuxna människors subjektiva tänkande om och förhållningssätt till munhälsa för att belysa faktorer som bidrar till eller utgör hinder för förändring av handlingsberedsThe need, for health educational reasons, of obtaining a more adequate understanding of how people think and act in connection with questions of dental health and professional dental care has been emphasized. The present study examines the attitudes and conceptions of adult individuals regarding their own dental health, as well as measures they take to further it. The aim is to elucidate factors t
