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OBJECTIVE: An increased prevalence of atherosclerosis has been shown among patients with hypopituitarism. The aim of the present study was to assess whether patients with hypopituitarism experience increased cardiovascular, in particular cerebrovascular, mortality.DESIGN AND PATIENTS: Retrospective cohort study of mortality, 1952-1992, in 344 patients, of whom 130 were female, receiving convention
The effect of exposure to toluene on plasma concentrations of testosterone, prolactin, luteinising (LH) and follicle stimulating (FSH) hormones was investigated in 47 rotogravure printers (time weighted average air toluene below 80 ppm; blood toluene concentration post-shift 0.19-7.99 mumol/l) and compared with a reference group. Increasing exposure concentrations of toluene (concentrations less t
Background: The immunogenicity, safety, and efficacy of recombinant factor VIII (rFVIII) have gained increasing interest after the introduction of extended half-life products with various modifications of the rFVIII molecule, such as covalent attachment of polyethylene glycol (PEG). Anti-PEG antibodies may be associated with a temporary reduction of FVIII recovery, but according to previous studie
The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID-19 severity is unclear. In this population-based, nationwide study using multi-register data, we aimed to assess if OSA is a risk factor for COVID-19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish residents with COVID-19 infection January 2020–May 202
INTRODUCTION: Flexible bronchoscopy is regarded as a safe examination and is commonly used in the diagnostic work-up for lung diseases, but is also important in pulmonary research. We aimed to investigate participants' experiences when undergoing bronchoscopy in a research setting.METHODS: Participants were recruited from the Swedish CArdioPulmonary bioImage Study (SCAPIS). A subset from this coho
Study region: The Paranapanema River Basin, located in southeastern Brazil, is characterized by a cascade of large hydropower plants regulated by a nationally coordinated dispatch system. This basin is a representative case of reservoir-regulated rivers in the country, where multiple dams interact to supply electricity while reshaping natural flow regimes. Study focus: This study examines hydropow
A radiation detection system combining a single-sided silicon strip detector (SSSD) and a high-purity germanium (HPGe) COMPEX detector module together with its anti-Compton shield (ACS) was set up at Lund University for environmental sample measurements. This system enables high sensitivity ––-coincidence analysis, enhancing the identification level of radionuclides in environmental samples. A com
Corrosion of cables can result in brittle and unexpected failures and represents a critical concern for prestressed concrete bridges with post-tensioned (PT) tendons. In these structures, corrosion is typically facilitated by inadequate grout injection and/or the use of poor-quality mortar during construction. Such deficiencies create favorable conditions for corrosion initiation and propagation.
The angular correlations between charged Ξ baryons and associated identified hadrons (pions, kaons, protons, Λ baryons, and Ξ baryons) are measured in pp collisions at s = 13 TeV with the ALICE detector to give insight into the particle production mechanisms and balancing of quantum numbers on the microscopic level. In particular, the distribution of strangeness is investigated in the correlations
Many animals undergo irreversible ontogenetic color changes (OCCs), yet these changes are often overlooked despite their potential ethological relevance. The problem is compounded when OCCs involve wavelengths invisible to humans. Wall lizards can perceive ultraviolet (UV) light, and their conspicuous ventral and ventrolateral coloration—including UV-reflecting patched—likely serves social communi
Sodium ion batteries have been considered as promising alternatives to lithium ion batteries for large-scale renewable energy and smart grids applications due to their low cost and rich resources. However, critical drawbacks such as low energy density and poor stability are hindering their development and application. In this work, a stable symmetric sodium ion cell using sodium vanadium pyrophosp
The Australian Bogong moth (Agrotis infusa) is a small noctuid moth that undertakes annual, nocturnal migrations of up to 1000 km to escape the summer heat of its breeding grounds. The moths travel to cool alpine caves, where they enter a dormant state (aestivation) before returning to reproduce and die. During migration, their brains integrate magnetic and visual cues to guide their flight direct
Rationale: A care bundle approach to the management of spontaneous intracerebral hemorrhage (ICH) has been shown to benefit patients in low- and middle-income countries (LMIC), but uncertainty persists over the specific components and its applicability in high-income countries (HICs). Aims: An international collaborative initiative aimed at determining whether implementation of a care bundle impro
Ubiquitously used for monitoring pipelines and infrastructures, distributed fibre-optic acoustic sensing is becoming an emerging technology for earthquake monitoring thanks to the possibility to interrogate a large vast of distances with a dense number of sensing points in which an optical fiber cable can be retrofitted. Moreover, it can also be used as a tool by geophysicists for the characteriza
INTRODUCTION: The optimal depth for decompression stops is unclear. We hypothesize that a decompression stop at 1.3 bar, compared with 1.6 bar, decreases post-dive whole-body nitrogen washout volumes and venous gas emboli (VGE).METHODS: In this randomized crossover trial, divers performed wet air dives of 40 minutes at 3.4 bar (340 kPa) with a seven-minute-long decompression stop at either 1.3 bar
Background and purpose: Accurate grading and genotyping of gliomas are critical for tailoring personalized therapeutic strategies and predicting patient outcomes. This study investigates the potential of 5T glutamate chemical exchange saturation transfer (GluCEST) imaging in differentiating glioma grades and predicting pivotal molecular biomarker status. Methods: We first validated the specificity
Background: Recent advances have highlighted the potential of artificial intelligence (AI) systems to assist clinicians with administrative and clinical tasks, but concerns regarding biases, lack of regulation, and potential technical issues pose significant challenges. The lack of a clear definition of AI, combined with limited focus on qualitative research exploring clinicians' perspectives, has
