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Aims: To illustrate the importance of access to register data on determinants and predictors of study participation to assess validity of population-based studies. In the present investigation, we use data on sociodemographic conditions and disease history among individuals invited to the Swedish cardiopulmonary bio-image study (SCAPIS) in order to establish a model that predicts study participati
A high-order convergent and robust numerical solver is constructed and used to find complex eigenwavenumbers and electromagnetic eigenfields of dielectric objects with axial symmetry. The solver is based on Fourier-Nyström discretization of combined integral equations for the transmission problem and can be applied to demanding resonance problems at microwave, terahertz, and optical wavelengths. H
Background: Functional electrical stimulation (FES) can be applied as an assistive and therapeutic aid in the rehabilitation of foot drop. Transcutaneous multi-pad electrodes can increase the selectivity of stimulation; however, shaping the stimulation electrode becomes increasingly complex with an increasing number of possible stimulation sites. We described and tested a novel decision support sy
PURPOSE: It has been documented that testicular germ cell cancer (TGCC) patients may be at increased risk of developing emotional distress (EMD). Hence, the aim of the present study was to investigate whether EMD is related to the presence of hypogonadism, androgen receptor (AR) polymorphism and/or treatment intensity. PATIENTS AND METHODS: Three to five years after treatment, testosterone and lut
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.
Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos kvinnor världen över och den står för omkring 30% av all cancer hos kvinnor i Sverige. Varje år får ca 7000 kvinnor i Sverige diagnosen och man räknar att ca en av tio kvinnor insjuknar under sin livstid. Trots att så många får bröstcancer så är det betydligt färre kvinnor som dör av bröstcancer; för närvarande ca 1500 per The aim of this thesis was to study reproductive factors and genetic polymorphisms in relation to breast cancer risk and survival. An important component of this was to investigate the risk of specific breast cancer subgroups. The association between parity and breast cancer-specific survival was studied among 4,453 women diagnosed with breast cancer in Malmö, Sweden. It was found that: • Nullipar
HDL has anti-atherogenic properties, and plasma levels of HDL cholesterol correlate inversely with risk of coronary artery disease. HDL reportedly functions as a cofactor to the anticoagulant activated protein C (APC) in the degradation of factor Va (FVa). The aim of the present study was to elucidate the mechanism by which HDL functions as cofactor to APC. Consistent with a previous report, HDL i
OBJECTIVES: Meniscal pathology in which the aetiology is often unclear is a frequent finding on knee MRI. This study investigates potential risk factors for medial meniscal lesions or extrusion in middle-aged and elderly persons. METHODS: Prospective cohort study using population-based subjects from Birmingham, Alabama and Iowa City, Iowa, USA (the Multicenter Osteoarthritis Study). 644 men and
Objective. The aim of this study was to evaluate enterocystometry, voiding pattern and urine leakage of four types of orthotopic bladder substitute. Material and methods. At eight urological departments, 78 consecutive men were studied: 66 with an ileal neobladder [30 Studer pouches (S), 24 Hautmann pouches (H) and 12 T-pouches (T)] and 12 with a right colonic [Goldwasser type (G)] neobladder. Ent
Healthy first-degree relatives with heredity of type 2 diabetes (FH+) are known to have metabolic inflexibility when compared to subjects without heredity for diabetes (FH-). In this study, we aimed to test the hypothesis that FH+ individuals have an impaired response to exercise compared to FH-. 16 FH+ and 19 FH- insulin sensitive men similar in age, VO2peak and BMI completed an exercise interven
Glutamate is loaded into synaptic vesicles by vesicular glutamate transporters (VGLUTs), and alterations in the transporters expression directly regulate neurotransmitter release. We investigated changes in VGLUT1 and VGLUT2 protein levels after ischemic and excitotoxic insults. The results show that VGLUT2 is cleaved by calpains after excitotoxic stimulation of hippocampal neurons with glutamate,
Uppsatsens syfte är att studera manlig prostitution så som den framträder i svensk dagspress mellan åren 1993-2013 och därvid jämföra manlig heterosexuell respektive homosexuell prostitution. De frågeställningar som undersöks är vilken bild som framträder för dessa grupper, vilka likheter och skillnader som finns mellan dem samt vilken förklaring Connell och Hirdmans genusteori skulle ge till dessPurpose of this thesis is to study male prostitution as it emerges in Swedish newspapers between the years 1993-2013 , comparing male heterosexual and homosexual prostitution. The issues examined is the picture that emerges for these groups , what similarities and differences between them and what explanation Connell and Hird 's gender theory would give to these potential differences . To inve
In Sweden one of the most important aspects of risk consideration in land-use planning is managing risks associated with the road transport of dangerous goods. Investigating how consultants perform their risk assessments and comparing them with actual accident statistics allows for a quantitative evaluation of the quality of these assessments. The thesis compares consultants’ risk assessments with
This paper has been commissioned by the County administrative board of Skåne in order to provide them with a tool to support the evaluation of individual fire rescue services, according to the requirements of law 2003:778 1 chap 1 § concerning protection against accidents. Evaluation is understandably a key element in providing a functional service with perspective to enhance the abilities of the
During the fall of 2023, the Palestine solidarity movement grew as a response to Israel’s war on Gaza. The student movement for Palestine was an important part of the Palestine solidarity movement. Palestinagård demanded LU to comply with their demands: to stand in solidarity with Palestine and Israel’s systemic destruction of the education system (scholasticide), cut ties with complicit academic
To simulate subcutaneous injection pressure, numerical solvers are developed and subsequently used to train a predictive, data-driven surrogate model that delivers fast and reliable outputs. Different approaches are examined for solving a nonlinear partial differential equation that describes the pressure during subcutaneous injections over time and in a semi-infinite spatial domain. For the spati
Background: Abnormal P-wave morphology (PWM) has been associated with a history of atrial fibrillation (AF) in earlier studies. Although lone AF is believed to have substantial genetic basis, studies on associations between single nucleotide polymorphisms (SNP) linked to lone AF and PWM have not been reported. We aimed to assess whether SNPs previously associated with lone AF (rs2200733, rs1337633
Primary Sjögren’s syndrome (pSS) is an autoimmune disease, primarliy affecting women, characterised by inflammation and destruction of exocrine glands with a prevalence of 0.01-0.09%. About one-third of the patients also suffer from extraglandular manifestations e.g. inflammation in the lungs, kidneys, skin or nerves. Apart from dyness symptoms, patients often suffer from fatigue and pain. Little
Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patien
