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Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.
Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos kvinnor världen över och den står för omkring 30% av all cancer hos kvinnor i Sverige. Varje år får ca 7000 kvinnor i Sverige diagnosen och man räknar att ca en av tio kvinnor insjuknar under sin livstid. Trots att så många får bröstcancer så är det betydligt färre kvinnor som dör av bröstcancer; för närvarande ca 1500 per The aim of this thesis was to study reproductive factors and genetic polymorphisms in relation to breast cancer risk and survival. An important component of this was to investigate the risk of specific breast cancer subgroups. The association between parity and breast cancer-specific survival was studied among 4,453 women diagnosed with breast cancer in Malmö, Sweden. It was found that: • Nullipar
HDL has anti-atherogenic properties, and plasma levels of HDL cholesterol correlate inversely with risk of coronary artery disease. HDL reportedly functions as a cofactor to the anticoagulant activated protein C (APC) in the degradation of factor Va (FVa). The aim of the present study was to elucidate the mechanism by which HDL functions as cofactor to APC. Consistent with a previous report, HDL i
OBJECTIVES: Meniscal pathology in which the aetiology is often unclear is a frequent finding on knee MRI. This study investigates potential risk factors for medial meniscal lesions or extrusion in middle-aged and elderly persons. METHODS: Prospective cohort study using population-based subjects from Birmingham, Alabama and Iowa City, Iowa, USA (the Multicenter Osteoarthritis Study). 644 men and
Energy security has gained increasing prominence on the EU political agenda, but is often framed narrowly, in terms of import dependency or security of supply. In this paper we screen and scope out a more comprehensive suite of energy security aspects to be considered when assessing low-carbon energy scenarios and apply it using the EU Energy Roadmap as an example. Availability and affordability i
Recently, plasma soluble urokinase plasminogen activator receptor (suPAR) has gained interest as a marker of cardiovascular risk. suPAR is released through the cleavage of urokinase plasminogen activator receptor (uPAR), which is found in monocytes, activated T-lymphocytes and endothelial cells, all involved in atherosclerosis. suPAR levels have been well studied in plasma, but no studies have foc
This thesis is a contribution to the understanding of the life and work of Arnold Schoenberg as well as to musical hermeneutics. The aims are (1) to scrutinize Arnold Schoenberg’s marital crisis of the year 1908, (2) to probe into the meanings of some representative musical works during this very period, and (3) to compare features in Schoenberg’s life and his creative work. A number of documents
cancer_6MAJ2019_SKICKA.indd 1 P IT DOLUPTAE PORUM Nya strategier cancer mot Överlevarna | Mammografi | Råd till närstående NOBELPR ISET PÅ R IKT IGT HUR UPPSTÅR CANCER? NANOPARTIKL AR Forskning som gör hela skillnaden Plastantikroppar med uppdrag att hitta cancer Slump eller livsstil – vad vet vi? NyaNya strategierstrategierstrategierstrategier cancercancer motmot Överlevarna | Mammografi | Råd ti
https://www.vetenskaphalsa.se/wp-content/uploads/2019/05/cancer_6MAJ2019_WEBB.pdf - 2026-07-20
LUNDS TEKNISKA HÖGSKOLA LÖSNINGAR MATEMATIK ANALYS 1 Helsingborg 2025-01-17 1. a) 2 2 22 7 4 2 7 1lim ( 2) (2 2) 0x x x x b) 2 sinsin 12lim 2 2 2 x x x c) 3 60 1lim 1 x xx e e = 3 3 6 60 0 0 ( 1)3 1 3 2 1 1lim lim 1 1 0 3 ( 1) 3 ( 1) 2 2 2 x x x xx x e x e x x e x e d) 2 2 2 2 (2 7 4 ) (2 7 4 )lim 2 7 4 ( )
https://www.maths.lu.se/fileadmin/matematik_lth_hbg/Analys_1/Loesningar/LoesningarAnalys1-250117.pdf - 2026-07-20
Optical imaging utilize light to analyze biological tissues in detail, non-invasively and without harmful radiation. Examples include ultrasound optical tomography and photoacoustic imaging; both use a limited number of wavelengths. Diffuse reflectance spectroscopy, another optical technique, covers a continuous wavelength range, but without generating an image. This study focuses on extended-wave
Compacted Graphite Iron (CGI) represents a unique combination of the characteristics of grey and spheroidal cast irons, sparking significant interest over the past two decades, particularly as a favoured material in several automotive industry applications, including engine components and heavy-duty vehicle parts. Despite its growing prominence, the full potential of CGI remains underutilised, pri
Introduction: Diffuse peripheral neuropathy is a well-known complication of several conditions, whereas many patients have peripheral neuropathy of unknown etiology and pathophyisology. Increased knowledge of mechanisms may provide insight into enteric neuropathy with gastrointestinal dysmotility. The aim of the present systematic review was to identify mechanisms behind diffuse idiopathic periphe
Introduced social insects can be highly invasive outside of their native range. Around the world, the introduction and establishment of the eusocial bumblebee Bombus terrestris (L. 1758) (Hymenoptera: Apidae) has negatively impacted native pollinators and ecosystems. Understanding how morphological variation is linked to environmental variation across invasive ranges can indicate how rapidly speci
Samples of Fucus serratus and Fucusvesiculosus taken in Swedish coastal waters have beenanalysed for Gd by ICP-MS. The results for one site withfrequent sampling show significantly increasing levelsduring the last 30 years, most likely a result of theincreasing use of Gd-containing contrast agents for MR-imaging at hospitals and other health care institutions.Samples taken at the west-, south- and
Background and objective: To assess the effect of surgeon sex on short- and long-term outcomes after colon cancer resections. Methods: Clinical data of patients who underwent colon cancer resections between 2010 and 2020 at Helsingborg Hospital, Sweden, were retrospectively obtained from medical records. The sex of the surgeon of each procedure was recorded. Morbidity, mortality, and long-term sur
Aim: Aquatic-terrestrial transition zones contain features essential for many species that often benefit wetland biodiversity. Shallow flood-zone areas and reed beds are indicative of natural wetland habitats; however, how such features affect the native arthropod biodiversity in constructed wetlands is scarcely investigated. We asked how these shoreline features, as well as wetland shoreline prop
BACKGROUND: Residents struggle with advance care planning (ACP) discussions in the inpatient setting, and may not be aware of newer models for ACP that stress the importance of giving prognostic information and making a recommendation about cardiopulmonary resuscitation to patients and families.METHODS: A controlled study of a cognitive model for ACP embedded in a quality improvement (QI) project.
Background and purpose: Galectin-3 (Gal-3) is a pro-fibrotic β-galactoside binding lectin highly expressed in fibrotic liver and implicated in hepatic fibrosis. GB1107 is a novel orally active Gal-3 small molecule inhibitor that has high affinity for Gal-3 >1000-fold selectively over other galectins. The aim of this study was to characterise GB1107 and galectin-3 in vitro and in vivo in the contex
