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This dissertation concerns the relationship between sociology and everyday life and aims primarily to critically evaluate the positions taken in the theoretical discussion on sociological concept formation and its relation to everyday life and social sciences. The main theoretical positions in the debate are summarized in two ideal typological models: (1) The rationalist theory of an epistemologic

Biomarkers for organ damage and/or dysfuntion are used in almost all areas of medicine. The brain has eluded this technological development for some time. Recently, the S100B protein has been shown to be a promising marker of brain damage. However, before S100S can reach clinical reality, several problems must be solved. The specificity of S100B requires special investigative attention. Although t

Animal models of neurological deficits are essential for the assessment of new therapeutic options. It has been suggested that rats are not as appropriate as primates for the symptomatic modelling of disease, but a large body of data argues against this view. Comparative analyses of movements in rats and primates show homology of many motor patterns across species. Advances have been made in ident

Background: Recent evidence supports an association between systemic lupus erythematosus (SLE) and non-Hodgkin's lymphoma (NHL). Objectives: To describe demographic factors, subtypes, and survival of patients with SLE who develop NHL. Methods: A multi-site cohort of 9547 subjects with definite SLE was assembled. Subjects at each centre were linked to regional tumour registries to determine cancer

Objective. The phenotypic complexity, together with the multifarious nature of the so-called schizophrenic psychoses, limits our ability to form a simple and logical biologically based hypothesis for the disease group. Biological markers are defined as biochemical, physiological or anatomical traits that are specific to particular conditions. An important aim of biomarker discovery is the detectio

Wireless sensor networks are emerging as an important area for communications. They enable a wealth of new applications including surveillance, building control, factory automation, and in-vehicle sensing. The sensor nodes have to operate under severe constraints on energy consumption and form factor, and provide the ability for precise self-location of the nodes. These requirements can be fulfill

Value-based health care aims to bring together patients and health systems to maximize the ratio of quality over cost. To enable assessment of healthcare value in stroke management, an international standard set of patient-centered stroke outcome measures was defined for use in a variety of healthcare settings.

Ewing sarcoma (ES) is an aggressive sarcoma of bone and soft tissue occurring at any age with a peak incidence in adolescents and young adults. The treatment of ES relies on a multidisciplinary approach, coupling risk-adapted intensive neoadjuvant and adjuvant chemotherapies with surgery and/or radiotherapy for control of the primary site and possible metastatic disease. The optimization of ES mul

BACKGROUND Nivolumab was associated with higher rates of objective response than chemotherapy in a phase 3 study involving patients with ipilimumab-refractory metastatic melanoma. The use of nivolumab in previously untreated patients with advanced melanoma has not been tested in a phase 3 controlled study. METHODS We randomly assigned 418 previously untreated patients who had metastatic melanoma w

rs7629265 and AF Risk ObjectiveWe examined the association of rs7626962 (S1103Y) or rs7629265, a variant in high linkage disequilibrium with S1103Y (r(2) = 0.87 - 1), with sudden cardiac death (SCD) and atrial fibrillation (AF) among African Americans. BackgroundThe SCN5A missense variant S1103Y has been associated with SCD among African Americans in small case-control studies, but larger populati

MALDI Mass spectrometry imaging (MSI) provides a technology platform that allows the accurate visualization of unlabeled small molecules within the two-dimensional spaces of tissue samples. MSI has proven to be a powerful tool-box concept in the development of new drugs. MSI allows unlabeled drug compounds and drug metabolites to be detected and identified and quantified according to their mass-to

Popular Abstract in Swedish Avhandlingen omfattar två delstudier. Huvudfokus är en fältstudie, där syftet är att förstå obotlig sjukdom och döden som konkreta erfarenheter på aktörsnivå. Med hjälp av observationer och intervjuer följs nio döende, anhöriga och sjuksköterskor under en tid i familjens hem. Den andra delstudien är en diskursanalys av danska socialpolitiska rapporter om det palliativa The dissertation deals with two part-studies. The main focus is a field study the purpose of which is to understand incurable disease and death as hands-on experiences at the player's level. With the aid of observations and interviews, nine dying people, relatives and community nurses are followed in the families? homes over time. The second part-study is a discourse analysis of Danish health-poli

Background: Coronary heart disease (CHD) risk inversely associates with levels of high-density lipoprotein cholesterol (HDL-C). The protective effect of HDL is thought to depend on its functionality, such as its ability to induce cholesterol efflux. Materials and methods: We compared plasma cholesterol efflux capacity between male familial hypercholesterolaemia (FH) patients with and without CHD r

A garden G is populated by n≥1 n≥1 bamboos b1,b2,...,bn with the respective daily growth rates h 1 ≥h 2 ≥⋯≥h n h1≥h2≥⋯≥hn. It is assumed that the initial heights of bamboos are zero. The robotic gardener or simply a robot maintaining the bamboo garden is attending bamboos and trimming them to height zero according to some schedule. The Bamboo Garden Trimming Problem, or simply BGT, is to design

BACKGROUND: Distress-driven symptoms are prevalent among older primary care patients and account for a large percentage of office visits and increased medical costs. An experimental written self-disclosure protocol has been shown to reduce symptoms and use of health care services in healthy adults. Written self-disclosure as a method for reducing symptoms has not been evaluated in the primary care

Program/Project Purpose: Increased recognition of the global cancer burden and inequalities in care and outcomes have led to the growing field of global oncology, focused on strengthening health systems to improve cancer prevention and care. Motivated students and trainees are in need of pathways to approach these challenges. In 2012, Harvard Medical students formed Students for Global Oncology (S