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This chapter provides an overview of the multi-faceted landscape of methods used to study the steering effects of the Sustainable Development Goals. After a discussion of the political use of science and the complex relations between science and politics, the chapter showcases a selection of different methods that are employed to trace the steering effects of the Sustainable Development Goals. Sel
Objects created by 3D printers are increasingly used in various medical applications. Today, affordable 3D printers, using Fused Deposition Modeling are widely available. In this project, a commercially available 3D printer was used to replicate a conventional radiographic contrast detail phantom. Printing materials were selected by comparing their x-ray attenuation properties. Two replicas were p
Background: Mitral annular plane systolic excursion (MAPSE) and left ventricular (LV) early diastolic velocity (e’) are key metrics of systolic and diastolic function, but not often measured by cardiovascular magnetic resonance (CMR). Its derivation is possible with manual, precise annotation of the mitral valve (MV) insertion points along the cardiac cycle in both two and four-chamber long-axis c
States in the Global South are facing a double challenge of achieving socio-economic development while adapting to climate change impacts. This study maps to what extent Small Island Developing States (SIDS) manage to meet the Sustainable Development Goals (SDGs). The SIDS are at the front line of climate change and while they share numerous challenges, the SIDS are also a heterogeneous group cont
The Cherenkov Telescope Array (CTA) is a next generation ground-based very-high-energy gamma-ray observatory that will allow for observations in the >10 GeV range with unprecedented photon statistics and sensitivity. This will enable the investigation of the yet-marginally explored physics of short-time-scale transient events. CTA will thus become an invaluable instrument for the study of the phys
Recent observations of the gamma-ray source HAWC J2227+610 by Tibet AS+MD and LHAASO confirm the special interest of this source as a galactic PeVatron candidate in the northern hemisphere. HAWC J2227+610 emits Very High Energy (VHE) gamma-rays up to 500 TeV, from a region coincident with molecular clouds and significantly displaced from the nearby pulsar J2229+6114. Even if this morphology favour
High-energy gamma rays are promising tools to constrain or reveal the nature of dark matter, in particular Weakly Interacting Massive Particles. Being well into its pre-construction phase, the Cherenkov Telescope Array (CTA) will soon probe the sky in the 20 GeV - 300 TeV energy range. Thanks to its improved energy and angular resolutions as well as significantly larger effective area when compare
Background: Coarctation of the aorta (CoA), a congenital narrowing of the proximal descending thoracic aorta, is a relatively common form of congenital heart disease. Untreated significant CoA has a major impact on morbidity and mortality. In the past 3 decades, transcatheter intervention (TCI) for CoA has evolved as an alternative to surgery. Objectives: The authors report on all TCIs for CoA per
During the last decades, there has been continuous development of nationwide quality registries to assess healthcare and to do research in Sweden. An important background motive is the demographic transition resulting from an increasingly ageing population as one of the most important challenges of our time and a growing concern in many European countries and elsewhere. One condition for meeting t
Objective: We aimed to test whether region-specific factors, including spatial expression patterns of the tau-encoding gene MAPT and regional levels of amyloid positron emission tomography (PET), enhance connectivity-based modeling of the spatial variability in tau-PET deposition in the Alzheimer disease (AD) spectrum. Methods: We included 685 participants (395 amyloid-positive participants within
This thesis aimed to increase the understanding of pump physiology in the remodeled heart compared to normal pump physiology.Study I was a cross-sectional observatory study investigating the regional contributions to stroke volume in patients with heart failure prior to cardiac resynchronization therapy (CRT) and tested the hypothesis that this characterization of pumping could predict CRT respons
In 2019 and 2021, the European League for Rheumatism (EULAR) jointly with the European Renal Association (ERA) and the Kidney Disease: Improving Global Outcomes (KDIGO), respectively, released updated guidelines on the management of lupus nephritis (LN). The Immunology Working Group of the ERA reviewed and compared both updates. Recommendations were either consistent or differences were of negligi
The Cherenkov Telescope Array (CTA) will be the next generation ground-based observatory for very-high-energy (VHE) gamma-ray astronomy, with the deployment of tens of highly sensitive and fast-reacting Cherenkov telescopes. It will cover a wide energy range (20 GeV - 300 TeV) with unprecedented sensitivity. To maximize the scientific return, the observatory will be provided with an online softwar
Emerging data on T1 bladder cancer subcategorization (aka substaging) suggests a correlation with oncological outcomes. The International Society of Urological Pathology (ISUP) organized the 2022 consensus conference in Basel, Switzerland to focus on current issues in bladder cancer and tasked working group 3 to make recommendations for T1 subcategorization in transurethral bladder resections. For
Esophagectomy is a complex and complication laden procedure. Despite centralization, variations in perioparative strategies reflect a paucity of evidence regarding optimal routines. The use of nasogastric (NG) tubes post esophagectomy is typically associated with significant discomfort for the patients. We hypothesize that immediate postoperative removal of the NG tube is non-inferior to current r
Based on observations obtained with the Nordic Optical Telescope (NOT) we investigate the spectral variability of the Herbig Ae star RR Tau. This star belongs to the UX Ori family, characterized by very deep fadings caused by the screening of the star with opaque fragments (clouds) of the protoplanetary discs. At the moments of such minima one observes strong spectral variability due to the fact t
Increasing evidence emphasizes the importance of chemokines and chemokine receptors as regulators of bone remodeling. The C-C chemokine receptor 3 (CCR3) is dramatically upregulated during osteoclastogenesis, but the role of CCR3 in osteoclast formation and bone remodeling in adult mice is unknown. Herein, we used bone marrow macrophages derived from adult male CCR3-proficient and CCR3-deficient m
Denna uppsats undersöker de levda erfarenheterna hos japanska migranter i Sverige, en grupp som omfattar cirka 4 600 individer, varav nästan 80 procent har valt att permanent bosätta sig i Sverige. De återstående 20 procenten är tillfälliga invånare, som studenter, forskare eller utstationerade chefer, verksamma i något av de cirka 200 japanskägda företagen i landet. Till skillnad från andra europThis thesis explores the lived experiences of Japanese migrants to Sweden, a demographic that includes approximately 4,600 individuals, of whom nearly 80 percent chose to settle permanently in Sweden. The remaining 20 percent are temporary residents, as students, researchers, or as expatriate managers, working in one of the roughly 200 Japanese-owned companies in the country. In contrast to other
Användningen av fasad- och vindskyddsskivor i ytterväggskonstruktioner är i dag utbredd. Skivorna är monterade långt ut i ytterväggen och utsätts således för variationer i omgivande relativ fuktighet och temperatur. På senare tid har skador såsom buktning av skivorna och sprickbildning hos skivorna uppmärksammats. Skadorna kan bero på rörelserna hos skivorna och det är således av intresse att undeThe use of boards as facades and sheathing is today common practice. Facade and sheathing boards are located far out in the building envelope and are thus subjected to variations of the surrounding relative humidity and temperature. Recently different kinds of damage on the boards have been brought to attention. The damage is varying and include cracking or warping of the boards. The damage may de
