Filtyp
This thesis describes functional and structural studies of the human protein α1-microglobulin (A1M), an evolutionarily well-conserved 26 kDa plasma and tissue protein mainly synthesized in the liver. A1M belongs to the lipocalin protein family. Lipocalins share a very similar structur, an 8-stranded β-barrel forming a hydrophobic pocket. A1M has reductase and radical scavenging properties. A1M als
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors
Objective A common threonine481serine polymorphism (T481S) has been shown in vitro to strongly activate the chloride channel Kb (CLC-Kb) expressed in the kidney, and the 481S allele has been associated with human hypertension. The study aim was to evaluate the association of the T481 S polymorphism with blood pressure (BP) levels and the BP progression rate in Swedes. Design and methods The cardio
Background: Adjuvant chemotherapy (ACT) for breast cancer improves relapse-free survival (BCRFS) and overall survival. Differences in terms of efficacy and toxicity could partly be explained by the significant interpatient variability in pharmacokinetics which cannot be captured by dosing according to body surface area. Consequently, tailored dosing was prospectively evaluated in the PANTHER trial
Background: Vitamin D is crucial for mineralized tissue formation and immunological functions. The purpose of this study was to evaluate the association between vitamin D status and dental status in healthy children with vitamin D supplementation in infancy and at 6 years of age. Method: Eight-year-old children who had participated in a vitamin D intervention project when they were 6 years old wer
At the southern margin of permafrost in North America, climate change causes widespread permafrost thaw. In boreal lowlands, thawing forested permafrost peat plateaus (‘forest’) lead to expansion of permafrost‐free wetlands (‘wetland’). Expanding wetland area with saturated and warmer organic soils is expected to increase landscape methane (CH4) emissions. Here, we quantify the thaw‐induced increa
Background: Gastric ulcers are painful sores with discontinuity in the entire thickness of stomach lining. Proton pump inhibitors (PPIs) are among the major classes of drugs used in treatment of gastric ulcers by inhibiting H+/K+ATPase pump thus reducing acid secretion. The prototype of PPIs is omeprazole, one of its new derivatives, esomeprazole is known to have superior activity against NSAIDs i
Background: Novel efficacious treatments with long-term tolerability are needed for transplant-ineligible, newly diagnosed multiple myeloma (NDMM) patients. This phase 2 study evaluated the safety and efficacy of all-oral ixazomib-cyclophosphamide-dexamethasone (ICd) followed by single-agent ixazomib maintenance. Patients and methods: Patients were randomised (1:1) to receive 4.0 mg of ixazomib, 3
Purpose: Tasquinimod, a novel oral therapy targeting the tumor microenvironment, significantly improved progression-free survival (PFS) in a randomized, placebo-controlled phase II trial in men with metastatic castration-resistant prostate cancer (mCRPC). This phase III study was conducted to confirm the phase II results and to detect an overall survival (OS) benefit. Patients and Methods: Men wit
GaxIn(1−x)P nanowires with suitable bandgap (1.35-2.26 eV) ranging from the visible to near-infrared wavelength have great potential in optoelectronic applications. Due to the large surface-to-volume ratio of nanowires, the surface states become a pronounced factor affecting device performance. In this work, we performed a systematic study of GaxIn(1−x)P nanowires' surface passivation, utilizing A
PURPOSE: Cisplatin-based combination chemotherapy (CHT) is standard of care in metastatic urothelial cancer (mUC); however, no predictive molecular biomarkers are available for clinical use. The aim of this study was to investigate the impact of molecular subtypes in relation to treatment response and survival in patients with mUC treated with first-line CHT.PATIENTS AND METHODS: Molecular subtype
Objective. To investigate whether rates of cartilage loss differ in knees with frequent baseline pain versus those without pain, after adjustment for radiographic osteoarthritis (OA) stage. Methods. One knee in each of 718 Osteoarthritis Initiative participants was examined: 310 with calculated Kellgren/Lawrence (K/L) grade 2, 299 with calculated K/L grade 3, and 109 with calculated K/L grade 4. T
Objectives: Within the first phase of developing classification criteria for Early-stage Symptomatic Knee Osteoarthritis, among individuals with knee osteoarthritis (OA) we explored: 1) symptoms within the first year of noticing their knee(s); 2) features that indicated OA was the cause; and 3) timing and reasons that initially prompted seeking healthcare. Design: We conducted a cross-sectional on
Researcher Contact details Email: zvezda [dot] vankova [at] jur [dot] lu [dot] se Phone: +46 46 222 67 26Organisation Department of Law Room number: 386 Service point: 56 WebpageZvezda Vankovas profile in Lund University research portalOther affiliations Researcher Human Rights Law Profile area member LU Profile Area: Human rights Researcher Public International Law Researcher EU Law Associate pro
https://www.law.lu.se/zvezda-vankova - 2026-07-23
Researcher Contact details Email: zvezda [dot] vankova [at] jur [dot] lu [dot] se Phone: +46 46 222 67 26Organisation Department of Law Room number: 386 Service point: 56 WebpageZvezda Vankovas profile in Lund University research portalOther affiliations Researcher Human Rights Law Profile area member LU Profile Area: Human rights Researcher Public International Law Researcher EU Law Associate pro
https://www.humanrights.lu.se/zvezda-vankova - 2026-07-23
Senior lecturer, associate professor Contact details Email: jan-henrik [dot] nilsson [at] ses [dot] lu [dot] se Phone: +46 42 35 66 37Organisation Department of Service Studies Room number: E 333 WebpageJan-Henrik Nilssons profile in Lund University research portalOther affiliations Associate professor Department of Service Studies Affiliated CIRCLEI am an associate professor in economic geography
https://www.ses.lu.se/en/jan-henrik-nilsson - 2026-07-23
Professor Kontaktinformation E-post: sylvia [dot] schwaag_serger [at] ekh [dot] lu [dot] seOrganisation Ekonomisk-historiska institutionen Besöksadress: Scheelevägen 15 B, Lund Rumsnummer: Alfa 1:2083 Hämtställe: 10 WebbplatsSylvia Schwaag Sergers profil i Lunds universitets forskningsportalAndra roller Affilierad professor CIRCLE Publikationer Visar av publikationer. Sorterade efter år och sen ti
https://www.ehl.lu.se/sylvia-schwaag-serger - 2026-07-23
Here you can learn more about the opportunities for professional development at Lund University. Content on this page:Professional development at Lund UniversityKompetensportalen (Professional Development Portal)Compulsory coursesCostsCourses for international university staffManagement and leadership developmentFor teaching staffCareer paths within research and teaching at Lund UniversityInspirat
https://www.staff.lu.se/employment/professional-and-careers-development - 2026-07-22
Agenda 2030 Graduate School monthly newsletter #3 2023-03-12 Ylva van Meeningen Hi! As spring comes closer and closer, everything seem to be in a rush. Plants have a rush to burst through the ground. Birds start to sing and more and more intensively and people in general seem to have stuff that need to be don right here and right now. Do not forget to take time once in a while to appreciate smalle
