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Triosephosphate isomerase (TIM) is a key enzyme in glycolysis that catalyses the interconversion of glyceraldehyde 3-phosphate and dihydroxy-acetone phosphate. This simple reaction involves the shuttling of protons mediated by protolysable side chains. The catalytic power of TIM is thought to stem from its ability to facilitate the deprotonation of a carbon next to a carbonyl group to generate an
Amplification of the MYCN oncogene is found in ~20% of neuroblastoma (NB) cases and correlates with high-risk disease and poor prognosis. Despite the plethora of studies describing the role of MYCN in NB, the exact molecular mechanisms underlying MYCN’s contribution to high-risk disease are not completely understood. Herein, we implemented an integrative approach combining publicly available RNA-S
Armlängdsprincipen kan betraktas som en av de mest centrala principerna inom den internationella beskattningsrätten. I OECD:s modellavtal, som ligger till grund för utformningen av bilaterala dubbelbeskattningsavtal, stadgas armlängdsprincipen i artikel 9, den regel som tillåter korrigering av ett företags vinst när interna transaktioner prissatts på ett sätt som inte är armlängdsmässigt. SamtidigThe ALP can be considered one of the most significant principles within international taxation law. It is regulated under article 9 of the OECD MTC, which acts as a model for developing new bilateral tax treaties. According to article 9, the profit of an enterprise may be adjusted if the enterprise has been involved in transactions with an associated enterprise on conditions that are not of an arm
Alpha 1-Microglobulin (alpha 1-m), or protein HC, a low molecular weight plasma protein with immunoregulatory properties, was isolated from rat serum by affinity chromatography using Sepharose-coupled monoclonal anti-alpha 1-m antibodies. High molecular weight forms of alpha 1-m were then separated from the low molecular weight alpha 1-m by gel chromatography of the eluted proteins. The apparent M
Biosynthetic precursors of NAD+ can replenish a decreased cellular NAD+ pool and, supposedly via sirtuin (SIRT) deacetylases, improvemitochondrial function.Wefound decreased hepaticNAD+ concentration and downregulated biosynthesis in Bcs1lp.S78G knock-in mice with respiratory chain complex III deficiency and mitochondrial hepatopathy. Aiming at ameliorating disease progression via NAD+ repletion a
Adults with congenital heart disease (ACHD) usually have reduced aerobic exercise capacity compared with controls. However, their skeletal muscle function is less studied.
NGEN08_VT_2016_rapport NGEN08_VT_2016 Answer Count: 13 Do you think that the aim, as described above, has been reached well in this course? Do you think that the aim, as described above, has been reached well in this course? Number of Responses 1 0 (0,0%) 2 0 (0,0%) 3 0 (0,0%) 4 3 (23,1%) 5 10 (76,9%) Total 13 (100,0%) Mean Standard Deviation Do you think that the aim, as described above, ha
https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/course_evaluation_ngen08_vt2016.pdf - 2026-07-10
The terminal investment hypothesis predicts that individuals should invest more in their present reproduction if they are less likely to survive to future reproductive events. Infections, which reduce viability, may be used by individuals as a cue of a diminishing residual reproductive value and could therefore theoretically trigger an intensification of breeding effort. We tested this hypothesis
Superantigens are immune-stimulatory toxins produced by Staphylococcus aureus, which are able to interact with host immune receptors to induce a massive release of cytokines, causing toxic shock syndrome and possibly death. In this article, we present the x-ray structure of staphylococcal enterotoxin B (SEB) in complex with its receptors, the TCR and MHC class II, forming a ternary complex. The st
Genetic differentiation of Dactylorhiza majalis ssp. traunsteineri from the Alps, Scandinavia, and Britain was studied and compared with other allotetraploid members of the systematically challenging genus Dactylorhiza. One-hundred and eleven populations from altogether 18 taxa were analysed for eight polymorphic plastid markers and two size-variable fragments from the nuclear internal transcribed
Rapid, reliable diagnosis of tuberculosis is essential to initiate correct treatment, avoid severe complications, and prevent transmission. Conventional microbiological methods may not be an option if samples are formalin-fixed and paraffin-embedded (FFPE) for histopathological examination. With the demonstration of necrotizing granulomatous inflammation, tuberculosis becomes an important differen
A polyion-surfactant ion complex salt, cat-HECDS, has been synthesised, consisting of cationic hydroxyethyl cellulose w th dodecylsulfate counterions. Ternary phase diagrams have been established for aqueous mixtures of cat-HECDS with either the conventional surfactant NaDS or the polyelectrolyte cat-HECCl. Such mixtures represent the simplest possible aqueous mixtures of oppositely charged polyme
Background: Vascular access failure is a common cause of morbidity in patients with end-stage renal failure on hemodialysis (HD). Activation of the coagulation system and formation of a thrombus play important roles in recurrent arteriovenous fistula/graft (AVFG) failure. Thrombin in complex with thrombomodulin (TM) activates the anticoagulant protein C and creates activated protein C (APC), which
contact@ceciliasterner.com www.ceciliasterner.com +46-707-516207 2001 Publikation #14, Rollon, Malmö 2000 Gallery C. Hjärne, Helsingborg 2000 Shoot- Moving Pictures by Artists, biograf Spegeln, Malmö 2000 Aura, Krognoshuset i Lund 1999 Rollon, www.rollon.net 1999 South City Drawings, The Pineapple 1999 Rollon, Panora, Malmö 1999 Whiteout Greyout Blackout, Barbacka konsthall, Kristianstad 1997 Mike
https://www.khm.lu.se/sites/khm.lu.se/files/1997cv_cesilia_sterner.pdf - 2026-07-10
The Senegalese decision to brake off negotiations over a renewed fisheries agreement with the European Union in 2006 represents a puzzle since substantial economical gains are associated with an accord and because such agreements have been renewed with a certain degree of continuity in the past. In this thesis, it is argued that the Senegalese withdrawal can be understood as a response to solid do
22-24 August, 2018 Cardiff University, Wales, UK Conference Program 21st International Conference on Quality and Service Sciences QMOD 1 21st QMOD-ICQSS Conference The Quality Movement - where are we going? Past, Present, and Future Su Mi Dahlgaard-Park Dr. Professor Lund University Jens J. Dahlgaard Dr. Professor Linköping University The theme of the QMOD2018 conference invites participants to re
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/quality_2018_program_final_1.pdf - 2026-07-10
How can the low representation of women in politics in Bosnia-Herzegovina be understood and what can a different approach add to already existing approaches to make Bosnia-Herzegovina more gender equal in terms of political representation of the genders? There has been established a Gender Equality Law that demands a 40% gender quota of political representation, but the gender representation has o
