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Hormone-sensitive lipase: Molecular analyses of the human gene; structural and evolutionary aspects on expression, alternative splicing and cold adaptation

Popular Abstract in Swedish Allmän Introduktion Hormonkänsligt lipas (HKL/HSL) är det protein (enzym) som hydrolyserar (bryter ner) det fett som finns lagrat inne i fettcellerna i fettväven. HSL finns också i steroidproducerande vävnader, som t.ex. binjure, äggstockar, moderkaka och testikel, och har troligtvis en viktig funktion i steroidsyntesen i åtminstone vissa av dessa vävnader. Det är dock Hormone-sensitive lipase (HSL) is a key enzyme in adipose tissue that hydrolyses stored fat (triacylglycerol). The activity of HSL is under strict hormonal and neural control. Lipolytic agents, such as catecholamines, increase the cAMP levels, resulting in an activation of cAMP-dependent protein kinase (PKA), which in turn phosphorylates and activates HSL. This thesis describes the structural orga

Low and High Energy Ion Beams in Nanotechnology

In this thesis, two ways of fabrication of nanometer-sized semiconductor features are presented. Low Energy Ion Implantation (LEII) has been used to create shallow (sub-50 nm) and laterally small (5 m m – 200 nm) features by 10 keV As+ doping of B background doped Si. Surface topography and electrical modification has been characterised using Atomic Force Microscopy (AFM) and Scanning C

Clinical and Biological Aspects of Cardiovascular microRNA

Ischemic heart disease is the leading cause of death in high-income parts of the world and is caused mainly by atherosclerosis in the coronary arteries. The rupture of an atherosclerotic plaque with subsequent platelet activation and clot formation can lead to myocardial infarction (MI). Atherosclerosis is a complex process, which involves the accumulation and oxidation of low-density lipoprotein

Growth, Physics, and Device Applications of InAs-based Nanowires

This thesis is based on three different projects: 1) the epitaxial growth of nanowires using chemical beam epitaxy, 2) the study of electron transport through quantum dots and multiple quantum dots in nanowires at low temperature, and 3) the development of wrap gated nanowire field effect transistors. In the first part, a method of studying the diffusion of the source material on the substrate su

MHC and Transgenic Mice. A study into polymorphism and function of class I and class II molecules

Popular Abstract in Swedish Vi är under ständig attack från mikroorganismer som vill leva på oss och i oss. Vissa av dessa är vanligtvis nyttiga medan andra är sjukdomsframkallande. Kroppens försvar mot invaderande organismer består av många delar. Ytterst sitter huden som en mekanisk barriär, vi har slem och epitelceller i luftvägar och magtarmkanal samt skyddande ämnen i exempelvis tårvätska. I Transplantation antigens encoded in the major histocompatibility complex (MHC) bind peptides and present them to T cells. We showed that mouse T cells expressing transgenic human CD8 can recognise human MHC class I. Expression on mature T cells is sufficient for activation in a mixed lymphocyte culture but expression both on thymocytes and mature T cells is necessary for peptide specific MHC restr

The HR 1614 moving group is not a dissolving cluster

Context. The HR 1614 is an overdensity in velocity space and has for a long time been known as an old (2 Gyr) and metal-rich ([Fe=H] +0:2) nearby moving group that has a dissolving open cluster origin. The existence of such old and metal-rich groups in the solar vicinity is quite unexpected since the vast majority of nearby moving groups are known to be young. Aims. In the light of new and signifi

Prolonged repolarization in the early phase of ischemia is associated with ventricular fibrillation development in a porcine model

Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion

The confluence of Cloud computing, 5G, and IoT in the Fog

In the wake of the arrival of cloud computing, future applications are poised to become more resilient and adaptive by embracing elasticity in an osmotic manner. Although cloud computing is a strong attractor for application developers, thereare still unconquered performance frontiers. Latency-sensitive and missioncritical applications make up a significant portion of all software systems, and the

Processing and Storage stability of Skim Milk Powder : Monitoring Early and Advanced Stages of the Maillard Reaction

The non-enzymatic browning known as the Maillard reaction has been the subject of extensive investigation for decades. Studies have focused on areas such as changes in flavour, colour, texture, and the nutritional properties of food materials as a result of this reaction. However, this complex reaction between the amino acids in proteins and reducing sugars in carbohydrates, is still not fully und

Does the oversight model lead to power relations in terms of empowerment or responsibilization?

In public safety oversight authorities are traditionally assumed responsible of safeguarding operation and promoting safety by defining prescriptions and observing that they are complied with. Regulated entities on their side are assumed responsibility for complying. While this compliance-based approach has contributed to current levels of safety, it is increasingly debated that it has limitatio

SARS

SARS [Severe Acute Respiratory Syndrome] penetrated China in spring of 2003, created havoc in the social society, exposed weaknesses within the political system and pushed the nation towards a crisis of confidence. At the same time the crisis revitalised the Party's position, brought people from different social stratum together and had a beneficial impact on the populace's knowledge on he

När statens anställda gör fel - Tillämpning och avvägning av straffrättsligt- och arbetsrättsligt ansvar i offentlig verksamhet

För statligt anställda och statligt verksamma gäller speciella ansvarsregler. Uppsatsen inriktar sig på att utreda tillämpningen av tjänstefel och disciplinansvar. Det första är en straffrättslig sanktion då fel begåtts i tjänsten i samband med myndighetsutövning. Det andra är ett arbetsrättsligt/förvaltningsrättsligt administrativt förfarande som myndigheter kan tillgripa gentemot sina anställda For state employees and those who exercise public authority, special liability rules apply in regards to professional misconduct. The essay focuses on investigating the application of disciplinary offence (breach of duty) in both criminal law and labour law. Disciplinary offence in criminal law is regulated in the Penal Code (brottsbalken) which applies when the violation committed is made within

Children´s right to education, for whom ? A Minor Field Study - Nepal

The purpose of this essay is to examine how Nepal has implemented article 28 of the UN Convention on the Rights of the Child (CRC). The essay focuses on subdivision 1(a) in the article which establishes that all States Parties shall make primary education compulsory and free to all children within their country. Through the ratification of the CRC the Government of Nepal is under the obligation to

The Deaths of Resonant Planetary Systems

White dwarf stars represent the last evolutionary stage of most stars in the Universe. As many of half of these stars are known to have metals in their atmospheres, that must have entered the atmosphere recently. Some also have observable debris discs, hinting that remnant exoplanets provide an important puzzle piece. However, we do not know the full extent of their role, as it is very hard to obs

Role of transposable elements in regulating gene expression in developing Pleurodeles waltl embryos

How salamanders develop and regenerate with help from jumping genes Salamanders are famous for something most animals cannot do – they can regenerate lost body parts like limbs and tail, and even parts of their internal organs. They can reactivate genes used during early development and create cells that can proliferate and compensate for the loss. For decades, scientists have studied these anima

Inte utan min heder - om straffrättsliga förhållningssätt till hedersrelaterat våld

Hedersrelaterat våld är för svenskt vidkommande inte längre ett främmande begrepp eller fenomen. Inte desto mindre är ämnet politiskt laddat och debatten om hedersrelaterat våld är fortfarande högaktuell. Inte minst på det straffrättsliga området gör sig problematiken gällande och det tycks råda en oklarhet kring vilken betydelse heder bör ha i rättsliga sammanhang. Hedersrelaterat våld är ett kViolence in the name of honour is no longer an unknown concept or phenomenon in the Swedish society. Nevertheless, the issue is subject of an ongoing political debate. The problematic aspects of violence in the name of honour are evident within the criminal justice system and there appears to be inherent uncertainties regarding the role of honour in the legal context. Violence in the name of hon

Capacity-building for interdisciplinary research on aging and health – experiences of graduate level initiatives in a national and international context

Abstract Body:Starting out from a joint Nordic collaboration initiative in 2008 resulting in the development of a Nordic Master Program in Gerontology (NordMaG), followed by the establishment of graduate schools integrated with two national excellence centers for aging research in Sweden, in 2014 the Swedish National Graduate School for Competitive Science on Aging and Health (SWEAH) was establish

Straffrätt i senmoderniteten – Om normstyrning, symbolisk kriminalisering och utvidgningen av sexköpslagen

Sociologisk forskning beskriver samtiden som ett senmodernt samhällstillstånd, som kännetecknas av snabb förändring, individualisering, globalisering och osäkerhet inför framtiden. Ett av rättens syften är att påverka människors beteenden, vilket kanske tydligast manifesteras genom straffrätten. Detta examensarbete undersöker hur straffrättens mål att påverka normer och styra beteenden tar form i Sociological research describes contemporary society as a condition of late modernity, characterized by rapid change, individualisation, globalisation, and uncertainty about the future. One of the purposes of law is to influence human behaviour, insofar as this is possible. A function that is perhaps most evidently manifested through criminal law. This thesis examines how criminal law’s aim to sha

Microsoft Word - masterthesis-feb 2016.docx

Microsoft Word - masterthesis-feb 2016.docx Master’s Dissertation Engineering Acoustics INVESTIGATION OF THE INFLUENCE OF INCIDENT ANGLE AND FREQUENCY DEPENDENCE OF A CEILING ABSORBER ON ROOM ACOUSTIC DESCRIPTORS ARNHEIDUR BJARNADOTTIR Report TV BA -5041 A R N H EID U R B JA R N A D O TTIR IN V ESTIG A TIO N O F TH E IN FLU EN C E O F IN C ID EN T A N G LE A N D FR EQ U EN C Y D EPEN D EN C E O F

https://www.akustik.lth.se/fileadmin/tekniskakustik/publications/tvba5000/webTVBA5041.pdf - 2026-05-28

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xpTVSM-4011 (2024-02) BACHELOR’S DISSERTATION AT STRUCTURAL MECHANICS EXAMENSARBETE I HÖGSKOLEINGENJÖRSUTBILDNINGEN VID LTH, CAMPUS HELSINGBORG DIVISION OF STRUCTURAL MECHANICS Faculty of Engineering LTH, Lund University, Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.byggmek.lth.se BERÄKNINGSVERKTYG FÖR VÄGSTOLPAR BAKGRUND Fackverksstolpar och KKR-st

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/bachelorprojects_THID/descriptions/xpTVSM4011.pdf - 2026-05-28