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Genomics-driven discovery of novel drug leads in underexplored microorganisms

Underexplored Gram (-) bacteria as a new source of natural products. Microorganisms produce an impressive array of structurally diverse and complex natural products with industrially-important properties. Microbial natural products therefore continue to be an important source of clinical drug candidates. While natural products from a few soil Gram (+) bacteria, together with their biosynthetic pa

A Case Study to develop and test GIS/SDSS methods to assess the production capacity of a Cocoa Site in Trinidad and Tobago

Pritam Kumarsingh A Case Study to develop and test GIS/SDSS methods to assess the production capacity of a Cocoa Site in Trinidad and Tobago Trinidad and Tobago has achieved world-wide affirmation for its unique fine and flavour cocoa (Theobroma cacao). This classification of cocoa commands price premiums on the global market. However, the industry has declined over years. Investors and farmers

Amyloid Aggregation in Alzheimer’s and Parkinson’s Diseases

Many evidence supports the notion that protein aggregation in the brain leads to neurodegenerative diseases, characterized by progressive degeneration of neuron structure and function in the brain. Protein aggregation causes a variety of diseases such Alzheimer’s disease (AD) and Parkinson’s disease (PD). Generation of extracellular amyloid-beta (Ab) plaques and aggregation of α-synuclein (α-syn),Several studies suggest that protein aggregation in the brain leads to neurodegenera-tive diseases. Two examples of this are seen in the neuropathological hallmarks of Parkinson’s disease (PD) and Alzheimer’s disease (AD) in the form of a-synuclein (a-syn) and amyloid-beta (Ab) plaques, respectively. However, an overlap of these pa-thologies has been observed in more than 50% of AD cases. This res

Influence of surgeon-related factors on outcome after colon cancer resection

Poor postoperative outcomes following colon cancer (CC) resection are influenced by multiple factors, including both patient-related characteristics as well as surgeon-related factors. However, the influence of surgical specialization, surgeon resection volume and surgeon gender on patient’s postoperative out- come, after complex procedures such as emergency CC resection, remains incompletely unde

Postoperative Weight Loss After Antiobesity Medications and Revision Risk After Joint Replacement

Importance: The 2023 American College of Rheumatology and American Association of Hip and Knee Surgeons Clinical Practice Guideline concluded that obesity alone should not delay joint replacement. Therefore, a substantially increased utilization of joint replacement among patients with obesity could be expected. However, patients with obesity are at increased risk of revision, posing unique challe

The EGF-like Modules of Anticoagulant Protein S. Studies of Ca2+ binding and module interactions

Popular Abstract in Swedish I samband med en kärlskada startar en kaskad av reaktioner som leder fram till bildandet av ett blodkoagel. Det är viktigt att bildandet av blodkoagel begränsas till det skadade området. Blodkoagulationen är därför reglerad av antal antikoagulanta system av vilka det viktigaste är protein C systemet. I detta system samverkar aktivt protein C (APC) tillsammans med ett an

Lunds-universitets-magasin-9-2006

lum_2006_09 LUM Lunds universitets magasin | Nr 9 | 2006 Frisk Med Fart Mögel på Theologicum Honeth lämnar LU efter 16 år LUM nr 9 | 2006 kroppskonta kt LUM nr 9 | 2006 Vad har före detta ärkebiskopen KG Hammar och den finska dansaren Virpi Pahkinen gemensamt? Jo, båda uppträdde vid Sandblomdagen, ett arrangemang i skärningspunkten mellan medicin och humaniora. Kropp och själ, vårt ansvar för eg

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-9-2006.pdf - 2026-05-28

Biobank report 2019

Microsoft Word - Biobank report 2019.docx MultiPark Biobank 1. Short description of the platform MULTIPARK'S BIOBANK SAMPLE COLLECTION Steering group: Maria Swanberg (coordinator), Oskar Hansson, Andreas Puschmann, Håkan Widner and Per Odin. Design and access to samples MultiPark's biobank sample collection (MPBC) is a resource that serves three major research areas: Biomarkers, Epidemiology and G

https://www.multipark.lu.se/sites/multipark.lu.se/files/biobank_report_2019.pdf - 2026-05-28

A study of the urinary cotinine in the employees deriving from the exposure to nicotine at the Nicorette patch and the Nicorette gum production at Pfizer Health AB, Helsingborg

Air sampling and biological sampling have been performed to examine the exposure to nicotine in the Nicorette patch and Nicorette gum production at Pfizer Health AB in Helsingborg, Sweden. For this purpose stationary and personal sampling equipment have been used. At the Nicorette patch production, XAD-2 tubes were used to sample nicotine vapor and at the Nicorette gum production Teflon filters we

Project Financa for Nuclear Power

As energy demand soars to new levels in heavily industrialised European countries, difficult decisions have to be made on how to ensure sufficient future energy capacity. The decision of the EU to put nuclear energy back on the agenda as a means of solving this issue must be seen against the backdrop of the debate over climate change and the outspoken policy to substantially reduce greenhouse gas

TISSUE MICROARRAY PERSPECTIVES ON CYCLIN D1 IN BREAST CANCER: Progression, prognosis and prediction

Breast cancer is a truly heterogenous disease, reflected in the existence of a wide spectrum of phenotypic subsets of tumours with varying intrinsic aggressiveness as well as ability to respond to a given treatment. Recent advances in large-scale genomic and proteomic screening techniques have confirmed this heterogeneity also at a molecular level, but there is still a bottleneck to be overcome be

Financial Applications of Markov Chain Monte Carlo Methods

Popular Abstract in Swedish Avhandlingen omfattar fyra artiklar inom empirisk finansiell ekonomi. Det första kapitlet är en kort sammanfattning av avhandlingens innehåll. Det andra kapitlet, Dynamic Portfolio Selection: The Relevance of Switching Regimes and Investment Horizon. (samförfattad med Birger Nilsson) undersöker dynamiskt portföljval och efterfrågan på tidsdiversifiering då aktieavkastnThis thesis consists of four empirical studies on financial economics. The first chapter contains a short summary of the thesis. The second chapter Dynamic Portfolio Selection: The Relevance of Switching Regimes and Investment Horizon (co-authored with Birger Nilsson) investigates the questions of dynamic portfolio selection and intertemporal hedging within a Markovian regime-switching framework.

Mycophenolic Acid Exposure after Administration of Mycophenolate Mofetil in the Presence and Absence of Ciclosporin in Renal Transplant Recipients

Background and objective: The pharmacokinetics of mycophenolic acid (MPA) are complex, with large interindividual variability over time. There are also well documented interactions with ciclosporin, and assessment of MPA exposure is therefore necessary when reducing or stopping ciclosporin therapy. Here we report on the pharmacokinetic and pharmacodynamic behaviour of MPA in renal transplant patie

Probiotics and berry-associated polyphenols: catabolism and antioxidative effects

Popular Abstract in Swedish Yttre faktorerna i omgivningen som UV-strålning från solen, rökning, läkemedel, maten och påfrestande livssituationer kan leda till att kroppens celler börjar överproducera molekyler som kallas syrefria radikaler. Dessa molekyler reagerar kemist mycket lätt med omgivande ämnen. När syrefria radikaler bildas i kroppen i normala mängder ingår de som en del av immunförsvarOxidative stress can cause damage to DNA, proteins and lipids and is associated with inflammation and various human diseases as cancer, atherosclerosis, and autoimmune diseases. Polyphenol-rich diet, such as fruits and berries, may act as antioxidants and prevent oxidative stress and, thereby, associated diseases. Administration of lactic acid bacteria (LAB) can affect the microflora in the gastro

Planktfbv018full 0

untitled HORIZONS Toward an ecologically meaningful view of resource stoichiometry in DOM-dominated aquatic systems MARTIN BERGGREN1*, RYAN A. SPONSELLER2, ANA R. ALVES SOARES1 AND ANN-KRISTIN BERGSTRÖM2 1 DEPARTMENT OF PHYSICAL GEOGRAPHY AND ECOSYSTEM SCIENCE, LUND UNIVERSITY, SE-223 62 LUND, SWEDEN AND 2 DEPARTMENT OF ECOLOGY AND ENVIRONMENTAL SCIENCE, UMEÅ UNIVERSITY, SE-901 87 UMEÅ, SWEDEN

https://www.nateko.lu.se/sites/nateko.lu.se/files/planktfbv018full_0.pdf - 2026-05-28

CEC Internal Investigation

Utredningsrapport - CECs nätverksorganisation inom en ny institution 42 Reg. No. STYR 2022/291 Date 2022-11-14 Investigation of how the CEC’s activities related to the coordination of major research programmes and multidisciplinary collaboration platforms can be organised if the departmental structure changes Summary The investigation has studied how the activities of the Centre for Environmental

https://www.science.lu.se/internal/sites/science.lu.se.internal/files/2023-01/CEC%20internal%20investigation.pdf - 2026-05-28

Guidelines-for-student-welfare-reviews-regarding-the-student-work-environment

MergedFile Page 1 of 3 Vice-Chancellor DECISION Reg. no STYR 2023/1421 Date 21 December 2023 Guidelines for Student Welfare Reviews Regarding the Student Work Environment at Lund University Background Lund University’s vision is to be a world-class university that works to understand, explain and improve our world and the human condition. A prerequisite for a successful organisation is that it is

https://www.staff.lu.se/sites/staff.lu.se/files/2024-03/guidelines-for-student-welfare-reviews-regarding-the-student-work-environment.pdf - 2026-05-28

MRSN01 Literature

MRSN01 Literature MRSN01 Literature Literature MRSN01, HUAMAN RIGHTS STUDIES, Feminist Political Philosophy, 7.5 credits. Approved by the Department of History Board 2020-12-04. Reference works Garry, Ann; Serene J. Khader, Alison Stone. The Routledge Companion to Feminist Philosophy. Abingdon: Routledge, 2019. ISBN 9780367257989. 754 pages. Free online access. Alcoff, Linda & Potter, Elizabeth. F

https://www.ht.lu.se/media/utbildning/dokument/kurser/MRSN01/20211/MRSN01_Litteraturlista_VT21.pdf - 2026-05-21

No title

DIVISION OF STRUCTURAL MECHANICS Lund University, Faculty of Engineering (LTH), Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.byggmek.lth.se xpTVSM-5209 (2015-10) MASTER’S DISSERTATION AT STRUCTURAL MECHANICS DEPARTMENT OF CONSTRUCTION SCIENCES | FACULTY OF ENGINEERING | LUND UNIVERSITY MATTIAS LILJA PRESENTATION Spring 2016 REPORT Will be published

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/descriptions/xp5209.pdf - 2026-05-25