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Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti-seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and long-lasting solutions. By addressing the underlying c
Radiotherapy Physics Innehåll 1. Bakgrund 2. Grundläggande dosimetri 3. Radiobiologi 4. Radioterapiprocessen 5. Klinisk dosimetri 6. Behandlingsoptimering 1. Bakgrund 4 http://www.radiofysik.se http://www.cancerfonden.se/ Cancer http://www.cancerfonden.se 5 http://www.cancerfonden.se/ Cancer http://www.cancerfonden.se 6 Antal cancerfall 2012: 57270 Beräknad 5-års överlevnad 72% http://www.cancerfo
https://www.msf.lu.se/sites/msf.lu.se/files/1._introduktion.pdf - 2026-07-23
Background: The treatment goal of early rheumatoid arthritis is remission. This study reports remission rates in clinical practice using a cohort of patients with early rheumatoid arthritis. Methods: 698 patients with early rheumatoid arthritis were included. Mean age at inclusion was 58 years and mean disease duration was 6.4 months; 64% of the patients were women, 56% were positive for antibodie
BACKGROUND: A synthetic oxytocin analogue, barusiban, was shown to potently inhibit oxytocin-induced activity of myometrium from term pregnant women. The responsiveness to vasopressin was not influenced by the compound. OBJECTIVE: To test the effect of barusiban and a reference compound, atosiban, on oxytocin-induced activity of myometrium from women at preterm pregnancy in comparison to myometriu
Abstract Determination of the respiratory tract deposition of airborne particles is critical for risk assessment of air pollution, inhaled drug delivery, and understanding of respiratory disease. With the advent of nanotechnology, there has been an increasing interest in the measurement of pulmonary deposition of nanoparticles because of their unique properties in inhalation toxicology and medicin
The solar proxy Be-10, measured in natural archives, has previously been assumed to lag solar activity by 1-2 yr. This reflects its residence time in the stratosphere where its main source lies. This study, based on a 30-yr global model simulation of the atmospheric transport of Be-10, shows that the stratospheric fraction of production varies significantly with the phase of solar activity. This l
There are several academical explanations of the phenomenon panic, mainly defined by behaviorists. However, these definitions tend not to be widely used or accepted by the public. While most of the behaviorists suggest that panic rarely occurs during fire and evacuation, the general view mostly differs and is essentially made up by media. This study reviews the different opinions of panic among pr
Studies have indicated that transportation noise is associated with higher cardiovascular mortality, whereas evidence of noise as a risk factor for respiratory and cancer mortality is scarce and inconclusive. Also, knowledge on effects of low-level noise on mortality is very limited. We aimed to investigate associations between road and railway noise and natural-cause and cause-specific mortality
The article investigates the reception of Carl Snoilsky’s Svenska bilder (Swedish Pictures) in Swedish schools, from the 1890s until today, in the light of the concept of cultural memory. For more than half a century, Snoilsky’s cycle of poems, depicting important events and figures in Sweden’s early modern history, belonged to the literary school canon; three special school editions were publisheThe article investigates the reception of Carl Snoilsky’s Svenska bilder (Swedish Pictures) in Swedish schools, from the 1890s until today, in the light of the concept of cultural memory. For more than half a century, Snoilsky’s cycle of poems, depicting important events and figures in Sweden’s early modern history, belonged to the literary school canon; three special school editions were publishe
Rat hepatocyte monolayers were cultured in the presence of 1-10% lipoprotein-deficient foetal calf serum. This increased the uptake and degradation of chylomicron remnant cholesteryl ester significantly. The increase occurred at all cell densities, i.e. also with less dense cultures where the basal rate of uptake per mg protein was highest. This indicates that tissue culture medium content of lipo
Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with type 2 diabetes (T2D) and 24,440 non-diabetic control participants from 5 ancestries. We identify gene-level associations of rare variants (with minor allele frequencies of less than 0.5%) in 4 genes at exome-wide si
Theoretical approaches to learning in practice-based jazz improvisation contexts include situated learning and ecological perspectives. This article focuses on how interest-driven, self-sustaining jazz learning activities can be matched against the concepts of stolen knowledge (Brown & Duguid, 1996) and landscape of learning (Bjerstedt, 2014). Based on an extensive interview study with Swedish
Parkinson’s disease (PD) patients frequently develop cognitive impairment. There is a need for brief clinical assessments identifying PD patients at high risk of progressing to dementia. In this study, we look into predicting dementia in PD and underlying structural and functional correlates to cognitive decline in PD. We included 175 patients with PD, 30 with PD dementia, 51 neurologically health
To predict maximal exercise capacity, we have developed the rating of perceived capacity (RPC) scale, based on metabolic equivalents (METs). MET values from 1 to 20 were listed on a progressive scale and linked to physical activities. Test subjects rated their perceived capacity by choosing the most strenuous activity and the corresponding MET value that they could sustain for 30 min. In order to
A rheological method for screening water soluble polymers intended for fouling prevention of membranes is investigated.Viscosity is measured of mixtures between polymers (neutral Dextran T500 positively charged DEAE-dextran and negatively charged dextran sulphate) and proteins (BSA, ovalbumin, pepsin and lysozyme).The method is sensitive enough to detect interactions between the polymers and the p
Syftet med uppsatsen är att bidra till en reflektion och diskussion kring meningsbegreppet i dagens humaniora, och mera specifikt inom dess posthumanistiska rörelse. Min tes är att meningsbegreppet är teoretiskt underutvecklat inom posthumanismen i allmänhet, och att det i själva verket använder sig av en Deleuziansk förståelse av mening utan att göra det explicit eller reflektera närmare över d
This thesis investigates the development of labor market policies directed at immigrants in Sweden, during the period of 1968-2010. The theoretical framework is built around three distinct ideas concerning the concept of citizenship – one libertarian, one empowering and a last one called caring, in the sense that it emphasizes the responsibility of society. My material consists of government publi
