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PURPOSE: Reliable molecular diagnostic tools are still unavailable for making informed treatment decisions and monitoring the response in patients with castration resistant prostate cancer. We evaluated the significance of whole blood circulating androgen receptor transcripts of full length (AR-FL) and splice variants (AR-V1, AR-V3 and AR-V7) as biomarkers of abiraterone acetate treatment resistan
We report the implantation of the Berlin Heart EXCOR (Berlin Heart, Berlin, Germany) as a pediatric biventricular assist device in a 10-month-old boy with primary graft failure after cardiac transplantation. The EXCOR was successfully used as a bridge to cardiac retransplantation. The pneumatically driven paracorporeal device supported the patient for 165 days until another suitable heart was obta
Pulmonary regurgitation (PR) is a common residual lesion and major determinant of outcome following surgical repair for tetralogy of Fallot. We sought to longitudinally study a previously described echocardiographic index as a correlate of PR measured by cardiac magnetic resonance imaging (CMR). We conducted a retrospective longitudinal study of patients with baseline and follow-up echocardiogram
Accurate evapotranspiration (ET) estimation is vital for hydrological modeling, yet remotely sensed ET (RS-ET) products are often limited by algorithmic uncertainties and sensor biases. To mitigate error propagation and better capture spatial patterns, this study introduces the Composite Efficiency of Absolute ET and Spatial Autocorrelation (CEASA) —a dual-constraint framework that integrates abso
To assess the prognostic importance of high-sensitive C reactive protein (hsCRP) in patients with mild to moderate aortic valve stenosis during placebo or simvastatin/ezetimibe treatment in Simvastatin and Ezetimibe in Aortic Stenosis (SEAS).
The speed-reducing effect of speed humps during darkness is important to ensure a consistent speed reduction and a decreased probability of accidents during darkness. This study examined the effects of speed humps, compared with a control location, on a residential road in Sweden with light-emitting diode (LED) street lighting and a 30 km/h posted speed limit. Hypotheses tested were that: (I) vehi
Background: A consistent imaging biomarker to standardize the evaluation of change in bone scan is an unmet need for patients (pts) with bone metastasis. BSI is quantitative interpretation of bone scan in pts with metastatic prostate cancer (mPCa). Here we have performed analytical and clinical studies to evaluate the change in computer automated BSI as a consistent imaging biomarker in pts with m
Several yeast species, usually engineered by humans in order to produce compounds of biotechnological interests, are currently used as cellular factories. This thesis presents two main themes. In the first, Saccharomyces cerevisiae is used for bio-ethanol production from lignocellulose hydrolysates and in the second Pichia pastoris is used for the heterologous expression of human ameloblastin. Th
NyhetsbrevVT15 Nyhetsbrev - Öresundsnätverket för kønshistorisk forskning Våren 2015 Öresundsnätverket för kønshistorisk forskning samlar forskare från olika discipliner i syfte att utveckla och stärka kønshistorisk forskning på båda sidor om Öresund. Kalendarium på båda sidor av sundet: “Racial politics, neoliberal rationalities and political activism” Med: Suvi Keskinen, University Lecturer in S
https://www.cors.lu.se/sites/cors.lu.se/files/nyhetsbrevvt15.pdf - 2026-07-24
Background Previous studies have indicated that vitamin K deficiency is common in non-bleeding critically ill patients with slightly prolonged prothrombin time-international normalized ratio (PT-INR). It has never been investigated thoroughly whether the administration of vitamin K to these patients could affect their PT-INR. Therefore, the aim of this registry study was to evaluate changes in PT-
Digitalization is shaping the discipline and practice of marketing. Not only does digitalization shape how we shop and consume everything from music to food and mobility services (Cochoy, Hagberg, McIntyre, & Sörum, 2017; Fuentes, Hagberg, & Kjellberg, 2019; Guyader, 2018; Schneider & Eli, 2022), but it has also fundamentally transformed the practices of marketing. Digitalization has c
Title: Underprissättning på den svenska marknaden - går den att förutspå? Seminar date: 2019-06-04 Course: FEKH89, Bachelor Degree Project in Financial Management, 15 ECTS Authors: Ebba Halvarsson, Erika Langåker och Sigrid Jonsson Advisor: Maria Gårdängen Keywords: Underpricing, Initial public offering, Ex ante, Nasdaq Stockholm, Nasdaq First North, Multiple regression, Asymmetric information Pur
In nature, bacteria usually exist as mixed-species biofilms, where they engage in a range of synergistic and antagonistic interactions that increase their resistance to environmental challenges. Biofilms are a major cause of persistent infections, and dispersal from initial foci can cause new infections at distal sites thus warranting further investigation. Studies of development and spatial inter
Bis(phosphinidene)-capped triiron carbonyl clusters, including electron rich derivatives formed by substitution with chelating diphosphines, have been prepared and examined as proton reduction catalysts. Treatment of the known cluster [Fe3(CO)9(µ3-PPh)2] (1) with various diphosphines in refluxing THF (for 5, refluxing toluene) afforded the new clusters [Fe3(CO)7(µ3-PPh)2(κ2-dppb)] (2), [Fe3(CO)7(µ
Of 30 bacterial species tested 18 stimulated DNA synthesis in human blood lymphocytes. The maximum response was after 3-4 days of culture suggesting a mitogenic effect. This was confirmed by the induction of polyclonal antibody production shown by a plaque assay. Most bacterial species increased the DNA synthesis in B-enriched lymphocytes and unseparated lymphocytes but had negligible activity on
