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Råttan är en däggdjursart med en kort dräktighetstiden och föds därför mycket omogen. Den är vid födelsen naken, blind och döv och är helt beroende av sin moder för många funktioner, såsom näringstillförsel, termoreglering, urinering och tarmtömning. Under diperioden är råttans mag-tarmsystem och matsmältning helt anpassad till modersmjölkdieten. Bland annat är tarmens barriärfunktion omogen, vilk

Autoantibody-mediated diseases comprise a heterogeneous group of disorders in which the pathogenic potential of autoantibodies has been clearly demonstrated. In general, their treatment relies on the long-term use of systemic corticosteroids and other immunosuppressants that are associated with considerable adverse reactions. EndoS, an endoglycosidase derived from Streptococcus pyogenes, specifica

Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T

Lägg till titel Page 1 of 1 REGULATORY DOCUMENT COVER PAGE Quality Policy for Lund University Type of regulatory document: Policy Definition of the type of regulatory document: Policies express the management’s overall intended direction or values that are to be taken into account within the area covered by the policy, set frameworks for a specific course of action and constitute a strong recommen

https://www.staff.lu.se/sites/staff.lu.se/files/2025-02/quality-policy-for-lund-university.pdf - 2026-06-17

In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that prevent neuronal growth and synaptic plasticity. The brain's ECM plays a crucial role in network formation, development, and regeneration of the c

Bränsleceller är ett intressant alternativ till förbränningsmotorer då bränsleceller har en högre effektivitet, är miljövänligare samt tystare. Bränslen som diesel, bensin samt det undersökta bränslet Jet A1, innehåller olika svårreagerade svavelföreningar. Problemet med bränslena är att de har ett relativt högt svavelinnehåll. Svavelföreningarna riskerar att förgifta katalysatorerna i de nedströ

Accurate detection of SARS-CoV-2 neutralizing antibody (nAb) is critical for assessing the immunity levels after virus infection or vaccination. As fast, cost-effective alternatives to viral infection-based assays, competitive binding (CB) assays were developed to quantitate nAb by monitoring the ability of sera to inhibit the binding of viral spike (S) protein to the angiotensin converting enzyme

Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r

https://www.energy.lth.se/research/energy-storage-conversion - 2026-06-15

Streptococcus pyogenes is an exclusively human pathogen that can provoke mild skin and throat infections but can also cause fatal septicemia. This gram-positive bacterium has developed several strategies to evade the human immune system, enabling S. pyogenes to survive in the host. These strategies include recruiting several human plasma proteins, such as the complement inhibitor, C4b-binding prot