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Ground level ozone [ozone] is considered a harmful air pollutant but there is a knowledge gap regarding its long term health effects. The main aim of this study is to develop local Land Use Regression [LUR] models that can be used to study long term health effects of ozone. The specific aim is to develop spatial LUR models for two Swedish cities, Umea and Malmo, as well as a temporal model for Mal
This study sheds light upon how memes about rioting in present-day Belfast are read by their audiences. As such, it answers to a distinct research gap in the meme studies literature, which has mostly shied away from in-depth engagements with audiences, favouring instead the intertwined concepts ‘imagined audience’ and the ideological ‘directionality’ of memes. Drawing on semi-structured interviews
Anthropogenic activities threaten many wildlife populations by increasing mortality rates, making it crucial to identify the locations and causes of mortality to inform conservation actions. Technological advancements, such as GPS satellite tracking, enable precise recording of wildlife movements. High-resolution data from such devices can facilitate rapid carcass recovery and provide insights int
Non-covalently molecularly imprinted polymers (MIPs) for beta(2)-amino acids were prepared for the first time. N-(2-chlorobenzyloxycarbonyl)-(R)-beta(2)-homophenylalanine (N-2-ClZ-(R)-beta(2)-HPhe)was imprinted with methacrylic acid (MAA) and/or 4-vinylpyridine (4-VPy) as the functional monomers, with ethylene glycol dimethacrylate ( EDMA) as the cross-linker. The MIPs made with different ratios o
Digital elevation models (DEMs) can be captured and analysed by various methods. Elevation capturing with RTK-GPS and airborne laser scanning is presented and evaluated in terms of height accuracy of raw data and interpolated DEMs for study sites in Sweden and Germany. Applications for precision agriculture are based on the connection of land surface and the movement of water in the landscape. Thr
Both spring temperature and date of the first Starling Sturnus vulgaris egg were highly correlated between different study sites and weather stations in the southern half of Sweden. In southern Sweden, but not in northern Sweden, onset of breeding correlated strongly with spring temperature, particularly during the last ten days of April, the period that happens to coincide with the start of breed
Microsoft Word - Allmän studieplan, medicinsk vetenskap_1 juli 2021_till hemsidan.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se 1 1 Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: 2018-06-11 Revid
Microsoft Word - Bilaga 8. Allmän studieplan, medicinsk vetenskap_2021_beslutad.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se 1 1 Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: 2018-06-11 Revider
Microsoft Word - Allmän studieplan_medicinsk vetenskap 2019.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: Fastställd av Forskarutbildningsnämnden de
Microsoft Word - Allmän studieplan_medicinsk vetenskap_rev 2019-12-03_klar.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se 1 1 Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: 2018-06-11 Reviderad: 2
Microsoft Word - Allmän studieplan, medicinsk vetenskap_1 juli 2022doc.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se 1 1 Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: 2018-06-11 Reviderad: 2018-
Microsoft Word - Allmän studieplan, medicinsk vetenskap_1 januari 2023_slutlig version.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se 1 1 Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: 2018-06-11
Popular Abstract in Swedish Immunförsvaret har till uppgift att skydda kroppen mot främmande mikroorganismer såsom bakterier och virus. En rad olika celler, vävnader samt organ samarbetar för att utforma ett väl fungerande immunförsvar. Det är ytterst viktigt att immunförsvaret känner igen kroppsfrämmande ämnen (antigen), som till exempel bakterieceller, men också att det skiljer dessa från kroppsGeneration of long-lived plasma cells and memory B cells of high affinity takes place in germinal centers and depends on help from a specialized CD4+ T cell subset termed T follicular helper (Tfh) cells. These processes are crucial for long-term protection upon natural infection or in settings of vaccination, however they are also responsible for development of antibody-mediated autoimmune disease
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Målet med denna avhandling var att undersöka hur cancersjukdomar i barndomen och behandlingen av dessa påverkar olika aspekter av fortplantningsförmågan i vuxen ålder. Glädjande nog har andelen patienter som överlever cancer i barndomen de senaste decennierna ökat stadigt till nivåer som idag ligger på nästan 80%. Ökad överlevnad medfChildhood cancer (CC) survival rate has increased over the last couple of decades, today approaching 80%. Therefore more attention has been paid to late effects. One important issue for CC survivors (CCS) is impaired reproductive function. CC per se and/or its treatment can impair the reproductive ability by affecting sperm production, as well as by damaging sperm DNA. This is a matter of concern,
Pancreatic cancer is the fourth cause of cancer-related death with a 5-year survival rate less than 5%. Two of the risk factors are chronic pancreatitis and type 2 diabetes (T2D), which are believed to promote the tumour progression. Pancreatic cancer and its tumour microenvironment is characterised by a dense stroma, immune cell infiltration and poor vascularisation. This creates a favourable env
Popular Abstract in Swedish Pyrimidiner är DNA-byggstenar som är essentiella för cellens överlevnad och delning. I mänskliga celler finns pyrimidiner att tillgå antingen genom återupptag eller genom biosyntes (nysyntes). Biosyntesen av pyrimidiner sker i flera steg och i ett av dem spelar enzymet Dihydroorotat dehydrogenas (DHODH) en avgörande roll genom att katalysera en oxidationsreaktion. När cIn the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. Potent inhibitors were identified within three classe
Popular Abstract in Swedish Frontotemporal demens är ett sjukdomstillstånd där nervceller i hjärnans pann- (“fronto”) och tinninglober (“temporal”) förtvinar, vilket leder till en tilltagande cellförlust och uttunning av hjärnbarken i dessa områden. Till skillnad från Alzheimers sjukdom, den vanligaste demenssjukdomen, leder frontotemporal demens i första hand inte till försämrat minne och orienteThe present thesis explores alterations in brain morphology in the neurodegenerative disorder of frontotemporal dementia (FTD). With the aim to improve the clinical diagnostics of FTD, we explored the diagnostic potential of measuring morphological alterations in the white matter by diffusion tensor imaging (DTI)- MRI, compared with the more commonly used assessment of grey matter thickness and vo
Background: There are differences in drug use depending on non-medical factors such as age, gender and socioeconomic status. The combined effect of these factors, with adjustment for multimorbidity, is highly relevant to study to ensure equality in drug use. Objectives: 1. To examine drug use related to age, gender, income and education after adjustment for multimorbidity, in an entire adult popul
Popular Abstract in Swedish Den kroniska inflammation som ses hos personer med inflammatorisk tarmsjukdom är troligen en immunologisk reaktion riktad mot normala tarmbakterier. I denna process har monocyter/makrofager (särskild celltyp av vita blodkroppar) en central betydelse. Det är huvudsakligen makrofager i tarmslemhinnan som styr det immunsvar som utvecklas då tarmfloran kommer i kontakt med Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. This study aimed at exploring the effects and regulation of chronic inflammation in inflammatory
Popular Abstract in Swedish p53 Ñett protein som kan fŒ leukemiceller att bli mera mogna Vid akut leukemi ansamlas omogna blodceller med nedsatt fšrmŒga till utmognad och programmerad celldšd. Detta leder till frŒnvaro av normala blodceller, vilket Šr huvudorsaken till de infektioner och blšdningsrubbningar som utgšr leukemins frŠmsta symptom. Akut leukemi har hittills framfšr allt behandlats medThe terminal differentiation of leukemic cells is closely connected to their death. The concept of differentiation therapy originates from the idea that forced maturation of leukemic cells could induce cell death without the side-effects that are provoked by ordinary chemotherapy. The tumour suppressor protein p53 is a transcription factor, and can induce cell cycle arrest and apoptosis of maligna
