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Online dynamic flat-field correction for MHz microscopy data at European XFEL

The high pulse intensity and repetition rate of the European X-ray Free-Electron Laser (EuXFEL) provide superior temporal resolution compared with other X-ray sources. In combination with MHz X-ray microscopy techniques, it offers a unique opportunity to achieve superior contrast and spatial resolution in applications demanding high temporal resolution. In both live visualization and offline data

In situ assembly of bioresorbable organic bioelectronics in the brain

Bioelectronics can potentially complement classical therapies in nonchronic treatments, such as immunotherapy and cancer. In addition to functionality, minimally invasive implantation methods and bioresorbable materials are central to nonchronic treatments. The latter avoids the need for surgical removal after disease relief. Self-organizing substrate-free organic electrodes meet these criteria an

Solvent effect on equilibrium organization of confined polymers

The equilibrium organization of two polymers in strong confinement has been extensively investigated in the scope of simple models in the recent past, after it was suggested that the entropic repulsion between polymers could be a mechanism for chromosome separation in living cells. Despite many efforts, how solvent quality can manipulate separation or compaction for the formation of domains in a t

The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease

Prostate-specific antigen (PSA or hK3) is a glandular kallikrein with abundant expression in the prostate that is widely used to detect and monitor prostate cancer (PCa), although the serum level is frequently elevated also in benign and inflammatory prostatic diseases. PSA testing is useful for early detection of localized PCa and for the detection of disease recurrence after treatment. However,

Comparison of immunohistochemical and biochemical assay of steroid receptors in primary breast cancer - Clinical associations and reasons for discrepancies

Estrogen ( ER) and progesterone receptor (PgR) status was analysed in paraffin-embedded breast cancer material with immunohistochemical (IHC) technique and compared with corresponding analyses in cytosols ( CYT). ER showed the same status (positive/negative) with both methods in 88% of the samples (352/ 402). The concordance was also high for PgR status (81% [321/394]). Besides values near cut-off

Short Term Survival after Admission for Heart Failure in Sweden: Applying Multilevel Analyses of Discriminatory Accuracy to Evaluate Institutional Performance.

Hospital performance is frequently evaluated by analyzing differences between hospital averages in some quality indicators. The results are often expressed as quality charts of hospital variance (e.g., league tables, funnel plots). However, those analyses seldom consider patients heterogeneity around averages, which is of fundamental relevance for a correct evaluation. Therefore, we apply an innov

RF Characterization of Vertical Wrap-Gated InAs/High-κ Nanowire Capacitors

This paper presents RF as well as low-frequency capacitance–voltage (C–V) characterization of vertical wrap-gated InAs/high-κ nanowire MOS capacitors. A full equivalent circuit model for traps is used to fit the low-frequency C–V characteristics, from which the interface trap density (Dit) and border trap density (Nbt) are evaluated separately. The results show comparable Nbt but far lower Dit (<1

Effect and safety of duodenal levodopa infusion in advanced Parkinson's disease: a retrospective multicenter outcome assessment in patient routine care

Duodenal levodopa infusion represents an effective strategy to manage motor and non-motor complications in patients with advanced Parkinson's disease (PD). However, most published clinical series regard small numbers of patients and do not exceed 1 year follow-up. In this multi-national observational cohort study conducted in seven specialised PD clinics and university hospitals we assessed long-t

Fluorescence quenching in Zn2+-bis-terpyridine coordination polymers: a single molecule study

A Zn2+-bis-terpyridine coordination polymer is investigated by single-molecule fluorescence spectroscopy (SMS). The bis-terpyridine ligands of the coordination polymers bear conjugated chromophores connecting the terpyridine spheres of the ligands, which resemble structural features of MEH-PPV. To the best of our knowledge this paper presents the first systematic SMS study on Zn2+-bis-terpyridine

The Provision of Conflicting Public Goods. Incompatibilities among Trade Regimes and Environmental Regimes

From its early days, the academic debate on public goods has focused on discrepancies or trade-offs regarding the provision of public goods on the one hand and private goods on the other. However, both the extension of the public domain and an increasing interdependence in international relations clearly drive the expansion of an agenda in which there are a growing number of cases where public goo

Gender, body weight, disease activity, and previous radiotherapy influence the response to pegvisomant

Context/Objective: To effectively normalize IGF-I in patients with acromegaly, various covariates may affect dosing and plasma concentrations of pegvisomant. We assessed whether sex, age, weight, and previous radiotherapy influence dosing of pegvisomant in patients with active disease. Design: Data from 69 men and 49 women participating in multicenter, open-label trials of pegvisomant were retrosp

Intra- and inter-laboratory reproducibility of estrogen and progesterone receptor enzyme immunoassay in breast cancer cytosol samples--a Swedish multicenter study. Swedish Society of Cancer Study Group

Estrogen and progesterone receptor analysis results were compared within and between six laboratories in Sweden using frozen breast cancer cytosol samples, and the same technique (enzyme immunoassay, Abbott Laboratories). The concordance in receptor status (positive vs. negative) was excellent (98.4% (571/580)). The discordant results were attributable to values near cut-off (n = 4) or outliers (n

Archeological excavation monitoring using dense stereo matching techniques

Several new tools to obtain three-dimensional information from unorganized image sets are now available for the public use. The main advantage of this software, which is based on dense stereo matching, is the possibility to generate 3D content without the need of high-cost hardware (e.g. 3D scanning devices). Nevertheless, their use in real-world application domains (like cultural heritage) is st

Nyhetsbrev Januari 2026

Kära medlemmar i Nordic Network for Narratives in Medicine, Det nya året bekräftar på nytt hur viktigt det är med nordiska – starka – band! Vårt nätverk växer stadigt och jag påminner alla hur välkommet det är med bidrag till våra nyhetsbrev. Mejla mig om publikationer, anställningar, konferenser eller annat ni tror att era kollegor skulle uppskatta att läsa om. Och missa inte att vi nu har ett da

https://www.medicinsk-humaniora.lu.se/sites/medicinsk-humaniora.lu.se/files/2026-02/Nyhetsbrev%20januari%202026.pdf - 2026-05-11

The Potential Features of Civic Sympathy and Affect

This piece of work aims at gaining a better understanding of how cognitive and sensual experiences takes place when we interact within the social encounter processes of shared spaces. The structure of this thesis starts off with a theoretical review based on the aspects of social encounters divided into the following areas: affect theory, the ideal of sympathy, and situated multiplicity. These t

UniStem Day 2026 Program

UniStem Day 2026 Program.pdf Lund Stem Cell Center, Lund University Morning Session Afternoon Session 9:00 - 9:15 Opening by the UniStem Day 2026 Coordinator, Associate Professor Nicholas Leigh, Lund Stem Cell Center Welcome from the Co-Coordinator of Lund Stem Cell Center, Associate Professor Göran Karlsson 9:15 - 10:05 Dr. Pia Johansson, Lund Stem Cell Center “Introduction to Stem Cells” Chimezi

https://www.stemcellcenter.lu.se/sites/stemcellcenter.lu.se/files/2026-03/UniStem%20Day%202026%20Program.pdf - 2026-05-11

Welfare justifications and responsibility in political decision making - The case of Nudging*

Nudging, i.e. the framing of decision environments to exploit known behavioral biases in order to induce certain outcomes, has received considerable attention as a potential policy tool in recent years. Motivated as preserving freedom of choice while making people better off according to their own judgment, nudging seemingly comes at fairly little responsibility for the nudger, i.e. policy makers,

Joint Analog Beam Selection and Digital Beamforming in Millimeter Wave Cell-Free Massive MIMO Systems

Cell-free massive MIMO systems consist of many distributed access points with simple components that jointly serve the users. In millimeter wave bands, only a limited set of predetermined beams can be supported. In a network that consolidates these technologies, downlink analog beam selection stands as a challenging task for the network sum-rate maximization. Low-cost digital filters can improve t