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Hypophosphatemia attenuates improvements in vitality after intravenous iron treatment in patients with inflammatory bowel disease

Purpose: Iron deficiency anemia is common in people with inflammatory bowel disease (IBD), causing deterioration in quality of life, which can be reversed by treatment that increases iron stores and hemoglobin levels. The present post hoc analyses estimate health state utility values for patients with IBD after treatment with ferric derisomaltose or ferric carboxymaltose and evaluate the health do

Objectives, actors and accountability in quasi-markets: Studies of Swedish primary care

Following public sector reforms inspired by New Public Management, new structures and processes intended for actors to coordinate their activities have been introduced in the public sectors in Northern Europe since the 1980s. Partly, the focus on structural change has evolved around creating market-like structures.Quasi-markets can be regarded as a structure for governance where market mechanisms

Free radical production and ischemic brain damage: influence of postischemic oxygen tension

It is now becoming increasingly clear that free radicals contribute to brain damage in several conditions, such as hyperoxia and trauma. It has been more difficult to prove that free radical production mediates ischemic brain damage, but it has often been suggested that it may be a major contributor to reperfusion damage, observed following transient ischemia. Recent results demonstrate that cereb

Orthostatic Hypotension: Epidemiology, Prognosis, and Treatment.

Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing. Its prevalence is age dependent, ranging from 5% in patients <50 years of age to 30% in those >70 years of

Development and evaluation of a computer-based educational program for adults with congenitally malformed hearts

Background: There is a lack o educational material for adults with congenitally malformed hearts. Computer-based education has shown to have significant effects on knowledge and management of chronic diseases. Aim: The aim of this study was to develop and evaluate a computer-based educational program for adults with congenitally malformed hearts. Methods: The program was developed by a multidiscip

Occupational Accidents Profile of the Construction Industry in Sweden

In Sweden, accident statistics reveal little, if any, evidence of improvement in health and safety on construction sites. Accident statistics, which adopt a reactive approach, must not be looked upon as merely numbers and figures. They must be able to reveal the underlying factors contributing to the accidents. This paper aims to examine construction safety performance based on accidents data from

From discovery to justification : Outline of an ideal research program in empirical psychology

The gold standard for an empirical science is the replicability of its research results. But the estimated average replicability rate of key-effects that top-tier psychology journals report falls between 36 and 39% (objective vs. subjective rate; Open Science Collaboration, 2015). So the standard mode of applying null-hypothesis significance testing (NHST) fails to adequately separate stable from

User-related Assessment of the Highway Automation System of VW

The aim of the user-related assessment was to evaluate the effects on driver behaviour, experiences, reactions, expected effects and acceptance of the Highway Automation” system, developed by VW in sub-project 6 of the AdaptIVe IP. The driving functions were developed as level 3 (conditional automation) functions so the driver does not have to monitor the system while driving. The system provides

Palliative oxygen for chronic breathlessness : What new evidence?

Purpose of review Supplemental oxygen improves survival in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxaemia, but the effect of oxygen therapy in mild or moderate hypoxaemia to reduce symptomatic chronic breathlessness remains unclear. This review provides an overview of recent evidence about the role of oxygen therapy for the relief of chronic breathlessness in adva

"Everydays" (A Progression Inspired by Jerome Kern)

Shortly before Christmas 2012, in a Beijing flea market and at a price, I was offered a cache of more than two thousand moth-eaten surveillance (“stake-out”) logs from the early 1950s emanating with the Bureau of Public Security in the city of Harbin, Manchuria. Unable to figure out what to do with them, I turned the offer down. Only later did it dawn on the historian in me that the logs just migh

In hot pursuit: fluctuating mating system and sexual selection in sand lizards

A changing climate is expected to have profound effects on many aspects of ectotherm biology. We report on a decade-long study of free-ranging sand lizards (Lacerta agilis), exposed to an increasing mean mating season temperature and with known operational sex ratios. We assessed year-to-year variation in sexual selection on body size and postcopulatory sperm competition and cryptic female choice.

Health-related quality of life after chemotherapy cycle in breast cancer in Iran

Abstract in Undetermined The aim of this study was to compare the differences between the level of whole quality of life and its subscales after receiving two common treatment of breast cancer in women with early stage of breast cancer. A double-blinded cohort study was done in 100 breast cancer patients with node positive that used fluorouracil, doxorubicin, cyclophosphamide (FAC) and docetaxel,

Climatology of the Iberia coastal low-level wind jet: weather research forecasting model high-resolution results

Coastal low-level jets (CLLJ) are a low-tropospheric wind feature driven by the pressure gradient produced by a sharp contrast between high temperatures over land and lower temperatures over the sea. This contrast between the cold ocean and the warm land in the summer is intensified by the impact of the coastal parallel winds on the ocean generating upwelling currents, sharpening the temperature g

Dynamic-Electro Enhanced Chemotherapy brings relief to palliative patients with large tumour burden

Syftet med nuvarande arbetet är att genomföra en klinisk fallstudie som utvärderar begreppet Dynamisk-ElectroEnhanced Chemotherapy ™ (D-EECT). Tio patienter med plavocellkarcinom, åtta med bröstcancer och fem patienter med var och en som presenterade en annan typ av tumör, infördes i försöken initierade av fem olika cancercentra. Alla patienter fick Bleomycin och 2-3 behandlingstider med IQWave ™ The aim of the present work is to perform a clinical case study evaluating the concept of Dynamic-ElectroEnhanced Chemotherapy™ (D-EECT). Ten patients with squamous cell carcinoma, eight with breast cancer and five patients with each presenting a different type of tumour, were entered in the trials initiated by five different cancer centres. All the patients were given Bleomycin and 2 to 3 treatme

Free Guided Tours : Storytelling as a means of glocalizing urban places

This article poses the question of how storytelling takes place in free guided tours. It aims to explore guides’ contributions to the glocalization of urban places. Theoretically, the study departs from the concepts of glocalization, place, and storytelling. Empirically, it builds on data from Copenhagen, Berlin, Warsaw and Tallinn, collected by means of participant observations and document studi

Accessibility and quality of drug company disclosures of payments to healthcare professionals and organisations in 37 countries: A European policy review

Objectives: To examine the accessibility and quality of drug company payment data in Europe.Design: Comparative policy review of payment data in countries with different regulatory approaches to disclosure.Setting; 37 European countries.Participants: European Federation of Pharmaceutical Industries and Associations, its trade group and their drug company members; eurosfordocs.eu, an independent da

Patient-reported quality of life and hand disability in elderly patients after a traumatic hand injury - A retrospective study

Background: Hand injuries occur at any age and cause disability in hand and arm function as well as impaired quality of life, but no study has focused on hand disability and quality of life in the elderly after a hand injury. Globally, the population over 60 years of age is expected to double by 2050 and more hand injuries are estimated among the elderly population. Our goal is to obtain more info

Tillförlitlig global vegetationsinformation fran satellitdata-optimism eller realitet?

The continuous operation of the NOAA series of meteorological satellites from the early 1980s onward, and the use of time series of data from its AVHRR sensor have been instrumental in the development of a new paradigm in the area of global earth observation. The coarse spatial and high temporal resolution of the data contrasts sharply with the data characteristics of traditional earth resource sa

Analyzing the situation of older family caregivers with a focus on health-related quality of life and pain : A cross-sectional cohort study

Background: For a significant proportion of the older population, increasing age is associated with health problems and worsening health. Older family caregivers are largely responsible for care of next-of-kin living at home, which impacts their own physical and mental health both positively and negatively. However, evidence is insufficient regarding the health situation of older caregivers. The a