Filtyp
The major aim of the study was to investigate whether differences concerning acceptance of dental treatment and amnesia after rectal sedation with midazolam can be explained by temperament traits in the child. Fifty children (1.5- 4.0 years), consecutively referred for dental extractions because of dental trauma or caries, were sedated with midazolam 0.3 mg kg(1) rectally. Level of sedation (state
Objective: To examine and compare the adult outcome in a representative sample of hospitalized adolescent-onset psychoses including occupational and social aspects. Method: A total of 81 patients with a first episode of early-onset psychosis (before age 19 years) presenting to the University Hospital of Lund, Sweden, between 1982 and 1993 were followed up an average of 10.5 years (range 5.1-18.2)
ATP-sensitive K(+) channels (K(ATP) channels) of pancreatic beta-cells play key roles in glucose-stimulated insulin secretion by linking metabolic signals to cell excitability. Membrane phosphoinositides, in particular phosphatidylinositol 4,5-bisphosphates (PIP(2)), stimulate K(ATP) channels and decrease channel sensitivity to ATP inhibition; as such, they have been postulated as critical regulat
Objective: The objective of the present study was to evaluate the pharmacokinetics and the clearance pathways of rFVIIa after intravenous administration to haemophilia patients. Methods: Ten severe haemophilia patients were included in the study; all patients were intravenously administered a clinical relevant dose of 90 μg/kg (1.8 nmol/kg) rFVIIa. Blood samples were collected consecutively to des
Climate change influences population demography by altering patterns of gene flow and reproductive isolation. Direct mutation rates offer the possibility for accurate dating on the within-species level but are currently only available for a handful of vertebrate species. Here, we use the first directly estimated mutation rate in birds to study the evolutionary history of pied flycatchers (Ficedula
Northern peatlands store 300–600 Pg C, of which approximately half are underlain by permafrost. Climate warming and, in some regions, soil drying from enhanced evaporation are progressively threatening this large carbon stock. Here, we assess future CO2 and CH4 fluxes from northern peatlands using five land surface models that explicitly include representation of peatland processes. Under Represen
The dense accumulation of α-Synuclein fibrils in neurons is considered to be strongly associated with Parkinson’s disease. These intracellular inclusions, called Lewy bodies, also contain significant amounts of lipids. To better understand such accumulations, it should be important to study α-Synuclein fibril formation under conditions where the fibrils lump together, mimicking what is observed in
Supercritical heat transfer deterioration can be found in active regenerative cooling processes. Thermal pyrolysis occurs once the temperature of the hydrocarbon fuel exceeds a certain value. To investigate the influence of thermal pyrolysis on the heat transfer behavior and flow-upward characteristics in a rectangular channel, the wall temperature distribution, thermal acceleration, mass fraction
AIM: Self-expanding metallic stents (SEMS) as bridge to surgery have been questioned due to the fear of perforation and tumour spread. This study aimed to compare SEMS and stoma as bridge to surgery in acute malignant large bowel obstruction in the Swedish population. METHOD: Medical records of patients identified via the Swedish Colorectal Cancer Register 2007-2009 were collected and scrutinized.
This paper sets out to create an implementation for fingerprint-based positioning using massive multiple-input multiple-output (MIMO) technology, by means of deep convolutional neural networks (CNN), and utilizing the wireless channel state information (CSI). Due to the sheer volume of computational requirements imposed by CNN processing, an accelerator-assisted design is well-suited to the task a
The etiology of hereditary ataxia syndromes is heterogeneous, and the mechanisms underlying these disorders are often unknown. Here, we utilized exome sequencing in two siblings with progressive ataxia and muscular weakness and identified a novel homozygous splice mutation (c.3020-1G > A) in neurofascin (NFASC). In RNA extracted from fibroblasts, we showed that the mutation resulted in inframe ski
Background: Advanced interatrial block (aIAB), which is associated with incident atrial fibrillation and stroke, occurs in the setting of blocked interatrial conduction. Atrial amyloid deposition could be a possible substrate for reduced interatrial conduction, but the prevalence of aIAB in patients with transthyretin cardiac amyloidosis (ATTR-CA) is unknown. We aimed to describe the prevalence of
Purpose: Most studies on paediatric pharyngotonsillitis focus on group A streptococci. This study, however, analyses a broad spectrum of bacteria and viruses related to paediatric pharyngotonsillitis and evaluates their associated clinical symptoms and courses. Methods: This observational prospective study in primary healthcare includes 77 children aged < 15 with a sore throat and 34 asymptomatic
In the Ordovician limestone of the Thorsberg quarry (South Sweden), about 130 meteorites have been found. Among the extraterrestrial material, several terrestrial Cr-spinels and zircons have been found too. In particular, in the interval 416–447 cm above the Arkeologen bed, terrestrial Cr-spinels, compositionally different from previous studied Cr-spinels of the same sequence, are present. Previou
Railway traffic is growing, resulting in a highly interconnected train network. Due to the interdependence between trains’ activities, a better understanding of train passes and their effects can ensure dispatching decisions made have minimum risk of delays. The impacts of train pass on dwell time delays were investigated using historical Swedish railway operation data. Three scenarios were consid
Protected area networks help species respond to climate warming. However, the contribution of a site's environmental and conservation-relevant characteristics to these responses is not well understood. We investigated how composition of nonbreeding waterbird communities (97 species) in the European Union Natura 2000 (N2K) network (3018 sites) changed in response to increases in temperature over 25
Saltwater intrusion is the most challenging problem in coastal regions. To prevent saltwater intrusion, saltwater pumping from a barrier well is widely applied, which is a direct abstraction of intruded saltwater from a coastal aquifer. Owing to its easy installation, many studies have been carried out. However, quantitative relationships between barrier and inland production well have not been re
