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Social belonging as the main concern for achieving life satisfaction when adapting to parkinson’s disease

Parkinson’s disease (PD) is a complex, progressive neurological condition that impacts daily life and reduces life satisfaction (LS). To achieve and maintain high LS, persons with PD (PwPD) must go through a process of change to adapt to their new life situation. However, our knowledge about this process is very limited. The aim of this study was to investigate the process of change, and the main

PrSLoc : Sybil attack detection for localization with private observers using differential privacy

During the localization process in wireless networks, risks such as Sybil attacks and nodes’ location privacy leakage can exist due to the open and shared nature of wireless networks. However, it is challenging to obtain accurate location for sensor nodes while preserving the privacy of observer nodes who assist in sensor node localization while in the presence of Sybil attacks. Therefore, in this

Optical feedback control loop for the precise and robust acoustic focusing of cells, micro- and nanoparticles

Despite a long history and the vast number of applications demonstrated, very few market products incorporate acoustophoresis. Because a human operator must run and control a device during an experiment, most devices are limited to proof of concepts. On top of a possible detuning due to temperature changes, the human operator introduces a bias which reduces the reproducibility, performance and rel

Soil Organic Carbon Stocks Depend Differently on Physicochemical Features in Subtropical Seasonally Flooded Wetland and Non-flooded Shoreland Forest

In recent years, an increasing number of ecosystems are threatened by seasonal flooding, changing non-flooded shoreland (NF) into seasonally flooded wetland (SF), but the consequences of this hydrological change for soil organic carbon (SOC) dynamics remain unknown. In this study, we investigated how the SOC content was determined by flooding duration and soil physicochemical variables in adjacent

Design, evaluation, and in vitro–in vivo correlation of self-nanoemulsifying drug delivery systems to improve the oral absorption of exenatide

The ability to predict the absorption of exenatide (Ex), a GLP-1 analogue, after oral dosing to rats in self-nanoemulsifying drug delivery systems (SNEDDS), using in vitro methods, was assessed. Ex was complexed with soybean phosphatidylcholine (SPC) prior to loading into SNEDDS. A design of experiments (DoE) approach was employed to develop SNEDDS incorporating medium-chain triglycerides (MCT), m

Effects of ALS-associated 5'tiRNAGly-GCC on the transcriptomic and proteomic profile of primary neurons in vitro

tRNA-derived stress-induced RNAs (tiRNAs) are a new class of small non-coding RNA that have emerged as important regulators of cellular stress responses. tiRNAs are derived from specific tRNA cleavage by the stress-induced ribonuclease angiogenin (ANG). Loss-of-function mutations in the ANG gene are linked to amyotrophic lateral sclerosis (ALS), and elevated levels of specific tiRNAs were recently

Flip or Flop? : The Pacing Problems of European Systemic Risk GPAI Regulation

Drawing from socio-legal studies on technological governance and notions of the pacing problem between law and new technologies, this chapter addresses how generative AI is regulated in the EU AI Act. Specifically, it focuses on implications of the two-tiered approach to General Purpose Artificial intelligence (GPAI) models, where the top tier is adding obligations to producers of so-called “syste

The impact of macronutrient composition on metabolic regulation : An Islet-Centric view

Aim: The influence of dietary carbohydrates and fats on weight gain is inconclusively understood. We studied the acute impact of these nutrients on the overall metabolic state utilizing the insulin:glucagon ratio (IGR). Methods: Following in vitro glucose and palmitate treatment, insulin and glucagon secretion from islets isolated from C57Bl/6J mice was measured. Our human in vivo study included 2

Less frequent face looking in infancy is related to autism likelihood status but not diagnosis : A study of parent-infant interaction

Background: Previous research suggest that autistic children look less at faces than neurotypically developing children, but this finding is based predominantly on screen-based eye tracking studies, with unfamiliar faces used as stimuli. The aim of the current study was to assess 10-month-olds’ gaze to faces in a more naturalistic context - during free play with a parent - in relation to later aut

IMPLEMENTING NATIONAL POLICY AND LOCAL PLANNING - Swedish wind power development and third generation mobile phone system as cases

The paper analyses the permit process for Swedish wind power development in terms of two paradigms of spatial planning and environmental management, and makes a comparison with the Swedish 3G mobile phone infrastructure development. Swedish Parliament has set a goal of 10 TWh annually wind electricity for 2015, and the Swedish Energy Agency has proposed 30 TWh from wind power by 2020. The present

Microarrays based on affinity-tagged single-chain Fv antibodies: Sensitive detection of analyte in complex proteomes

Protein-based microarrays are among the novel class of rapidly emerging proteomic technologies that will allow us to efficiently perform global proteome analysis. However, the process of designing adequate protein microarrays is a major inherent problem. In this study, we have evaluated a protein microarray platform based on nonpurified affinity-tagged single-chain (sc) Fv antibody fragments to ge

Oral mucosal microvascular network abnormalities in de novo mutation achondroplasia

Approximately 90% of achondroplasia (ACH) cases are the result of a de novo mutation, with no phenotypical markers for the unaffected ACH parents being known to date. Here, the hypothesis of the presence of an oral mucosal microvascular abnormality in ACH children and unaffected ACH parents was tested. Two-dimensional vascular network geometry was analyzed in 15 children with sporadic ACH, 30 unaf

On the interaction between two fixed spherical particles

The variation of the drag (CD) and lift coefficients (CL) of two fixed solid spherical particles placed at different positions relative each other is studied. Simulations are carried out for particle Reynolds numbers of 50, 100 and 200 and the particle position is defined by the angle between the line connecting the centers of the particles and the free-stream direction (a) and the separation dist

The impact of male overweight on semen quality and outcome of assisted reproduction

It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass index (BMI) on semen quality and the outcome of assisted reproductive technology (ART). The aim of this study was to investigate whether increased male BMI affects sperm quality and the

Intrinsic femtosecond charge generation dynamics in single crystal CH3NH3PbI3

Hybrid metal-organic perovskite solar cells have astounded the solar cell community with their rapid rise in efficiency while maintaining low-cost fabrication. The intrinsic material photophysics related to the generation of free charges, their dynamics and efficiency, however, remains to be understood. As fabrication techniques improve, larger crystal grain sizes have been shown to be a critical

Thyrotropin receptor autoantibodies are associated with continued thyrotropin suppression in treated euthyroid Graves' disease patients

Antithyroid treatment effectively restores euthyroidism in patients with Graves' hyperthyroidism. After a few months of treatment, patients are clinically euthyroid with normal levels of thyroid hormones, but in many patients TSH levels remain suppressed. We postulated that TSH receptor autoantibodies could directly suppress TSH secretion, independently from thyroid hormone levels, via binding to

200212. deu. schedule syllabus

200212. D€. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start. # Session Required readings Session focus Module 1: Setting the stage 1 Money today, theory and practice April 20, 13.00-16.00 Anders Ögren, Ester Barinaga, Paul Stankovski & Christian Gehrmann Readings: • Werner, R.2014. Can

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200212._deu._schedule_syllabus.pdf - 2026-05-08