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Testicular germ cell cancer (TGCC) is the most common malignancy in young men. Genetic variants known to be associated with risk of TGCC only partially account for the observed familial risks. We aimed to identify additional polymorphisms associated with risk as well as histological and clinical features of TGCC in 367 patients and 214 controls. Polymorphisms in ESR2 (rs1256063; OR=0.53, 95% CI: 0

Uganda has fertile soils and climatic conditions well suited for cotton production. The country has a competitive advantage in the good intrinsic quality of its cotton, the cheap labour and the fact that cotton is handpicked. There is a ready market for the cotton once it is harvested and there are many areas of use, such as textile, medical supplies, cooking oil, soap and animal feed. In spite of

Moderate exercise is deemed beneficial for cognition due to increase in dopamine concentrations in the basal ganglia. Auditory white noise is beneficial for cognition, mainly for those with lower attentional ability, i.e. for those having lower tonic dopamine concentrations. For individuals with higher attention ability white noise can have a negative effect. In this thesis it was examined whether

Gränser mellan vegetationszoner fascinerar genom att på ett tydligt sätt påminna oss om sambanden som finns mellan det som lever och dess miljö. En av de mest påtagliga gränserna är den alpina trädgränsen, där fjällbjörkskogen gradvis övergår till kalfjäll. Den karga miljön som utgör kalfjället är starkt kopplat med temperatur och klimatförändringens ökade temperatur har medfört förändringar i träAerial photo interpretation shows a recent densification of trees has been occurring between 1960 and 2009 in the mountain birch (Betula pubescens ssp. czerepanovii) forest of the treeline ecotone in northern Swedish mountains. The correlation between treeline position and annual temperature is commonly accepted and advancing treelines are considered to be a useful indicator for monitoring climate

The European Myeloma Network has organized two workshops on fluorescence in situ hybridization in multiple myeloma. The first aimed to identify specific indications and consensus technical approaches of current practice. A second workshop followed a quality control exercise in which 21 laboratories analyzed diagnostic cases of purified plasma cells for recurrent abnormalities. The summary report w

Hummingbirds are specialized hoverers for which the vortex wake has been described as a series of single vortex rings shed primarily during the downstroke. Recent findings in bats and birds, as well as in a recent study on Anna's hummingbirds, suggest that each wing may shed a discrete vortex ring, yielding a bilaterally paired wake. Here, we describe the presence of two discrete rings in the wake

Genome-wide association studies have identified 32 loci influencing body mass index, but this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-analyzed associations between similar to 2.5 million SNPs and body fat percentage from 36,626 individuals and followed up the 14 most significant (P < 10(-6)) independent loci in 39,576 individuals. We confirmed a previou

Total and cause specific mortality and cancer morbidity were studied among 1929 asbestos cement workers with an estimated median cumulative exposure of 2.3 fibre (f)-years/ml (median intensity 1.2 f/ml, predominantly chrysotile). A local reference cohort of 1233 industrial workers and non-case referents from the exposed cohort were used for comparisons. The risk for pleural mesothelioma was signif

Spinach thylakoids were separated into grana core, grana margin, and two different stromal lamella fractions in the absence of detergents. The levels of all light-harvesting chlorophyll a/b-binding (LHC) proteins were determined in all fractions, and were normalised to the amount of Photosystem I (PS I) and Photosystem II (PS II) centres. PS Iβ in the stroma lamellae was found to have a full compl

A time-related deterioration in male reproductive function caused by exposure to endocrine disrupters, including persistent organochlorines (POCs), has been hypothesized. In animal studies, POCs were found to have adverse effects on male reproductive function. However, little is known about the impact of POC exposure on reproductive parameters in men. In a study of 305 young Swedish men 18-21 year

OBJECTIVES: The referrals of elderly for cardiac surgery are increasing. The aim of this retrospective study is to review the long-term survival and to identify causes of late death in elderly after cardiac surgery. DESIGN: Between 1990 and 1993, 130 octogenarians underwent cardiac surgery in our department. A majority (88%) had elective surgery. One hundred and nine patients (84%) were in New Yor

Popular Abstract in Swedish Modellering och krav för automation av gradningsprocessAn increasing number of robots have been used for the finishing of castings during recent years. This is mainly due to developments to overcome problems that restricted their use during the past decade. The major difficulties have been the need to control reaction forces during metal removing by grinding operations and the lack of tools designed specially for robots. The elimination of these two p

An effect of permeabilisation and lyophilisation of the yeast cells Hansenula polymorpha on their electrochemical behaviour in the presence of mediators, substrates (formaldehyde, glucose, methanol, ethanol), and cofactors (NAD(+), NADP(+), NADH, NADPH, glutathione) has been studied. Two amperometric techniques differing in the cell immobilisation methods were applied. The cells of a wild strain (

Cessation of smoking is followed by a rapid rise in plasma HDL concentrations. An earlier study has demonstrated a significant relationship between the increase in HDL concentrations and spontaneous changes in food intake, specifically an increased fat intake. In this investigation we have dissociated the effects of cessation of smoking as such from those of dietary alterations by monitoring plasm