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Hypothalamic pathology, metabolic dysfunction and psychiatric symptoms are part of Huntington disease (HD), which is caused by an expanded CAG repeat in the huntingtin (HTT) gene. Inactivation of mutant HTT selectively in the hypothalamus prevents the development of metabolic dysfunction and depressive-like behavior in the BACHD mouse model. The hypothalamic paraventricular nucleus (PVN) is implic

An increasing number of patients with central nervous system (CNS) tumour could survive to reproductive age. However, it is largely unknown whether the history of CNS tumour might affect pregnancy outcome. We aimed to explore the risk of being born pretem among children of CNS tumour survivors. By linking several nationwide registers in Sweden, we identified 1369 children whose parents were childh

In this article, we argue that Slow City processes in Halfeti are used as a strategy to preclude the uncertainty in its development path, especially in view of the effects of Birecik Dam on the town. By using Swyngedouw’s post-political critique, we further argue that Slow City’s goals to ensure sustainability in the context of Halfeti serve to depoliticize the problems related to infrastructure,

Studies of how contextual factors influence teachers’ approaches to teaching have chiefly focused on face-to-face teaching in physical campus contexts. This study advances understanding of how applicable this knowledge is in digital contexts. The study explores how university teachers perceive the differences between teaching in physical campus contexts and the digital teaching contexts found in o

The main purpose of this research is to investigate the genuine problems face by female teacher of Govt. Girls Primary schools and Federal Community Girl Primary School in F.R Peshawar. The main theme of this study is to investigate female teachers’ work related issues in government primary schools and federal community schools?, also what are the available facilities to female teaching staff at g

The aim of this essay is to analyse the role women play for the male Beats in Jack Kerouac's On the Road (1957) and how women, love and marriage are viewed in the text. The hypothesis that I argue for is that the male Beats' relationship to women is built upon an opposition. Their restless vagabond life with its characteristic search for "kicks" is contrasted with traditional and

The inner relative humidity (RH) and degree of saturation (S) of high-performance concrete cured for 2 years in water or 3% NaCl solution were measured at three different levels from the concrete surface (outer layer 0 to 16 mm, middle layer 16 to 32 mm, and inner layer 32 to 50 mm). The effects of many factors, such as water-to-cement (w/c) ratio, content of silica fume, and air content, were inv

It is unclear whether high levels of antigen-specific islet antibodies [GADA (glutamic acid decarboxylase 65 antibodies) and IA2-ab (protein tyrosine phosphatase-like protein antibodies)] predict beta-cell failure in patients with onset of diabetes in adult age. Therefore, GADA and IA2-ab levels at the diagnosis of diabetes were related to fasting plasma C-peptide levels 5 yr later in 148 patients

In boron neutron capture therapy (BNCT) the absorbed dose to the tumor cells and healthy tissues depends critically on the boron uptake. Pronounced individual variations in the uptake patterns have been observed for two boron compounds currently used in clinical trials. This implies a high uncertainty in the determination of the boron dose component. Ln the present work a technique known as prompt

Information on soil mineralogy is essential for weathering rate calculations. Quantitative mineralogical analyses are expensive and time-consuming, and thus indirect methods of determining the mineralogical composition are important, for example estimating the composition based on the elemental content in till (total concentrations), or based on information about the underlying bedrock. The minera

In this study the effect of strontium substitution on the hydrolysis of alpha-tricalcium phosphate (alpha-TCP) toward the formation of calcium deficient hydroxyapatite (CDHA) was investigated. For that purpose substituted alpha-TCP powders with 1, 5 and 10 mol% Sr substitution for Ca were synthesized by reacting at 1500 degrees C stoichiometric amounts of CaCO3, SrCO3, and Ca2P2O7, followed by rap

Titel: Assessing the marginal value of subsidiary ownership - A case study on Alfa Laval India Ltd Authors: Maria Björkander & Fredrik Runéus Tutors: Måns Kjellsson – PHD candidate, Department of Business Administration, Lund School of Economics and Management Anders Vilhelmsson – PHD, Department of Economics, Lund School of Economics and Management Thomas Thuresson – Chief Financial Officer,