Sökresultat

Background: Carriers of the transmembrane 6 superfamily member 2 E167K gene variant (TM6SF2EK/KK) have decreased expression of the TM6SF2 gene and increased risk of NAFLD and NASH. Unlike common 'obese/metabolic' NAFLD, these subjects lack hypertriglyceridemia and have lower risk of cardiovascular disease. In animals, phosphatidylcholine (PC) deficiency results in a similar phenotype. PCs surround

Objective: Genome-wide association studies (GWAS) have been successful at identifying associations with stroke and stroke subtypes, but have not yet identified any associations solely with small vessel stroke (SVS). SVS comprises one quarter of all ischemic stroke and is a major manifestation of cerebral small vessel disease, the primary cause of vascular cognitive impairment. Studies across neuro

I början av 2018 utbröt en debatt om kulturrådets utdelning av litteraturstöd i svenska dagstidningar. I samband med uttalanden från kulturminister Alice Bah Kuhnke menade vissa av bokmarknadens aktörer att litteraturstödet är utsatt för politisk styrning och att kvalitetskriteriet bortprioriteras. Uppsatsen undersöker de olika förväntningarna och föreställningarna som finns på litteraturstödet. J

Fastighetsmarknaden i Sverige omsätter ungefär 100.000 fastigheter till ett sammanlagt värde av 300 miljarder svenska kronor. Fastighetsöverlåtelsernas påverkan för individen och på samhällsnivå kan inte underskattas. Den digitaliserande trenden har påverkat denna bransch starkt internationellt och i Norge har lagändringar genomförts för att anpassa fastighetsöverlåtelsen till den moderna och digiThe real estate market in Sweden has a turnover of approximately 100,000 properties with a total value of 300 billion SEK. The impact of the property transfers on the individual and at the community level cannot be underestimated. The digitalisation trend has had a major impact on this industry internationally and in Norway, legislative changes have been made to adapt the property transfer to the

This multiple case study addresses the question concerning how multinational corporations handle their public affairs operations. In general, public affairs regard public private sector collaboration and include how companies can manage their governmental stakeholders. Nevertheless, is there a recipe for managing this more successfully? Public affairs have long been an issue for companies operatin

“The code that guides the Path” Geosmin is a volatile metabolite that smells like the earthy odorant that is mostly predominant after a heavy rain fall; what produces this intensive surge of geosmin in the air is from the spore producing family streptomycetaceae. Not only do these bacteria produce a scent that most people find pleasant to smell, they also play a key role in modern society. Why th

Titel: CSR i SMEs – En studie om uppfattning, motiv och hinder Seminariedatum: 30 maj 2013. Ämne/Kurs: Magisteruppsats Civilekonomprogrammet - Företagsekonomi, FEKN90 30 hp Författare: Henrik Halling, Erik Karlsson Handledare: Christine Blomqvist Fem nyckelord: corporate social responsibility (CSR), små och medelstora företag (SMEs), motiv, hinder och uppfattning. Syfte: Syftet med uppsatTitle: CSR in SMEs – A study of perception, motives and barriers. Seminar date: may 30th 2013 Course: Master Thesis in Business Administration - FEKN90 30 (ECTS) Authors: Henrik Halling, Erik Karlsson Advisor: Christine Blomqvist Five key words: corporate social responsibility (CSR), small and medium enterprises (SMEs), motives, barriers and perception. Purpose: The purpose of this stud

Den tilltalades tidigare brottslighet kan i svensk rätt påverka påföljdsbestämningen för ny brottslighet, dvs. straffmätning och påföljdsval, på främst tre sätt. I första hand kan den tidigare brottsligheten beaktas genom ett skärpt påföljdsval. I andra hand har rätten möjlighet att förklara villkorligt medgiven frihet förverkad. I sista hand finns det genom straffskärpning möjlighet att förlänga

OBJECTIVETo study the association between dietary flavonoid and lignan intakes, and the risk of development of type 2 diabetes among European populations.RESEARCH DESIGN AND METHODSThe European Prospective Investigation into Cancer and Nutrition-InterAct case-cohort study included 12,403 incident type 2 diabetes cases and a stratified subcohort of 16,154 participants from among 340,234 participant

Background: Dairy product intake may be inversely associated with risk of type 2 diabetes, but the evidence is inconclusive for total dairy products and sparse for types of dairy products. Objective: The objective was to investigate the prospective association of total dairy products and different dairy subtypes with incidence of diabetes in populations with marked variation of intake of these foo

Popular Abstract in Swedish Elektromagnetiska fält finns idag överallt och är en förutsättning för att det moderna samhället ska fungera. Utan att fundera närmare på det, använder vi oss ständigt av de elektromagnetiska fältens förmåga att trådlöst överföra information och energi. Några exempel är; uppvärmning av mat i mikron och på induktionshällen, samtal i mobiltelefonen, uppdatering av status In this thesis, an inverse source reconstruction method with great potential in radome diagnostics is presented. A radome is a cover that encloses an antenna in order to protect it from environmental influences. Radome diagnostics are acquired in the design process, the delivery control, and in performance verification of repaired and newly developed radomes. A measured near or far field may indic

OBJECTIVE The long-term association between dietary protein and type 2 diabetes incidence is uncertain. We aimed to investigate the association between total, animal, and plant protein intake and the incidence of type 2 diabetes. RESEARCH DESIGN AND METHODS The prospective European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct case-cohort study consists of 12,403 incident typ

Objectives: To compare the oldest old (85 years and above) in pain with those with no pain across gender, regarding demographic data, living conditions, social network/support, walking/mobility problems, fatigue, sleeping problems, depressed mood and quality of life (QoL). The aim was also to test how these variables were related to QoL among the oldest old in pain. Methods: The study comprised 16

Consistent but indirect evidence has implicated genetic factors in smoking behavior1,2. We report meta-analyses of several smoking phenotypes within cohorts of the Tobacco and Genetics Consortium (n = 74,053). We also partnered with the European Network of Genetic and Genomic Epidemiology (ENGAGE) and Oxford-GlaxoSmithKline (Ox-GSK) consortia to follow up the 15 most significant regions (n > 140,0

Background: Epidemiologic evidence of an association between fish intake and type 2 diabetes (T2D) is inconsistent and unresolved. Objective: The objective was to examine the association between total and type of fish intake and T2D in 8 European countries. Design: This was a case-cohort study, nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, with 3.99 m

Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans(1-3). We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we identified at genome-wide significance (P = 2.7 x 10(-8) to P = 2.3 x 10(-13)) four new PP loci (at

More than 100 loci have been identified for age at menarche by genome-wide association studies; however, collectively these explain only similar to 3% of the trait variance. Here we test two overlooked sources of variation in 192,974 European ancestry women: low-frequency proteincoding variants and X-chromosome variants. Five missense/nonsense variants (in ALMS1/LAMB2/TNRC6A/TACR3/PRKAG1) are asso