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To study which individual characteristics and environmental factors correlate with fear of moving outdoors and whether fear of moving outdoors predicts development of mobility limitation. Observational prospective cohort study and cross-sectional analyses. Community and research center. Seven hundred twenty-seven community-living people aged 75 to 81 were interviewed at baseline, of whom 314 took
Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying re
Concerns have been raised about the quality of reporting in nutritional epidemiology. Research reporting guidelines such as the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement can improve quality of reporting in observational studies. Herein, we propose recommendations for reporting nutritional epidemiology and dietary assessment research by extending the ST
This paper is about interdisciplinary common initiatives to enhance and encourage quality of engineering education nationwide, by means of a scientific approach to teaching. To reach innovative pedagogical approaches it is seen as important to stimulate collaboration and knowledge sharing across discipline borders. STEM, referring to the academic disciplines of science, technology, engineering, an
Within the hematopoietic system, the Notch pathway is critical for promoting thymic T cell development and suppressing the B and myeloid lineage fates; however, its impact on NK lymphopoiesis is less understood. To study the role of Notch during NK cell development in vivo, we investigated different NK cell compartments and function in Rbp-Jkfl/flVav-Cretg/+ mice, in which Rbp-Jk, the major transc
Infection represents an evolutionary arms race between pathogen and host. Thus, scientists find that pathogenic microbes have evolved elegant strategies to manipulate or avoid our immune system, allowing them to persist within the human population. This thesis is largely focused on how bacteria regulate and exploit the type I interferon (IFN) response in infected macrophages – a processes of centr
We develop an optimal control model for cost-effective management of pollution, including two state variables, pollution stock and ecosystem quality. We apply it to Baltic Sea pollution by nitrogen leachates from agriculture. We present a sophisticated, non-linear model of leaching abatement costs, and a simple model of nitrogen stocks. We find that significant abatement is achievable at reasonabl
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are neuronal survival molecules which utilize the Trk family of tyrosine kinase receptors. Using double-label in situ hybridization, we demonstrate that mRNAs for BDNF and its high-affinity receptor TrkB are coexpressed in hippocampal and cortical neurons. Also, a large number of neurons in these areas coexpress NGF and BDNF mR
Neuroanatomy suggests that adjacent neocortical neurons share a similar set of afferent synaptic inputs, as opposed to neurons localized to different areas of the neocortex. In the present study, we made simultaneous single-electrode patch clamp recordings from two or three adjacent neurons in the primary somatosensory cortex (S1) of the ketamine-xylazine anesthetized rat in vivo to study the corr
This thesis aims to contribute, both empirically and theoretically, to the field of study within Islamology that concerns contemporary Sufism in non-Muslim majority societies. It does so by investigating how activities and narratives provide meaning and identity for participants in the transnational Sufi movement Naqshbandi-Haqqani. This movement is led by the Turkish Cypriot Shaykh Muhammad Nazim
This chapter visits some of the fundamental concepts from platform economics, network effects, and network externalities. Further on, it discusses definitions of two-sided and multi-sided markets, how they are treated as business models. These concepts are further compared to the concept service ecosystem. A case of a payment service provider whose business model contributes to the growth of e-com
A new empirical method for in situ determination of the inventory of 137Cs in soil (ACs, kBq m−2) at grasslands and forests using a field-portable NaI(Tl) scintillation spectrometer-dosimeter was developed. The method is based on evaluation of the ambient dose equivalent build-up factor. The practical implementation of the new method with the spectrometer-dosimeter does not require a priori knowle
Background: Indoor lighting, exposure to outdoor daylight, physical activity and sleep interact to influence functioning, mood and cicadian rhythm. Older adults (≥ 65 years), who often spend more time at home, are less physically active and experience more sleep problems, could benefit from strategies to support behavioural change and self-managed modifications in the home. The study’s primary objBackgroundIndoor lighting, exposure to outdoor daylight, physical activity and sleep interact to influence functioning, mood and cicadian rhythm. Older adults (≥ 65 years), who often spend more time at home, are less physically active and experience more sleep problems, could benefit from strategies to support behavioural change and self-managed modifications in the home. The study’s primary objec
We document the socioeconomics of wind power expansion in Sweden using two metrics. First, we compute the difference in socioeconomic status (SES) between residents exposed to wind power (0-2 km from the closest turbine) and those not exposed. For each site, the metric is computed ten years prior until five years after construction. When the comparison group is other residents within the same muni
During WWII, the botanist Hylander (1943, 1949) studied the floristic composition of lawns in 249 landscape gardens mostly in Sweden and concluded that they all harboured multiple, but largely the same, non-native species and genotypes that had most likely been introduced together by the sowing of some im- ported grass seed mix. As demonstrated by the later additions by, for example, Ohlsén (1947)
Dyskinesia seen in the off-state, referred as graft-induced dyskinesia (GID), has emerged as a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. Although the mechanism underlying the appearance of GID is unknown, in a recent clinical study the partial 5-HT(1A) agonist buspirone was found to markedly reduce GID in three grafted patients, who showed signifi
The aim of this chapter is to illustrate the latent functions of projectification using local government practices as an example and explore organisational consequences of an increasing reliance on a project logic. Inspired by the institutional logic perspective, local government and their organisations are studied as sites where several, coexisting institutional logics are ‘available’ for civil sThe aim of this chapter is to illustrate the latent functions of projectification using local government practices as an example and explore organisational consequences of an increasing reliance on a project logic. Inspired by the institutional logic perspective, local government and their organisations are studied as sites where several, coexisting institutional logics are ‘available’ for civil s
We investigated bidirectional cross-linguistic influence on motion event (ME) expressions in bilingual speakers of two typological different languages (Talmy’s typology), Spanish (as L1) and English (as L2). Specifically, we investigated whether bilingual speakers struggle to learn ME expressions in the L2, and whether this process affects ME uses in the L1. Potential effects of L2 proficiency and
