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We show how a careful analysis of the behaviour of a parton shower Monte Carlo in the vicinity of the soft and collinear regions allows one to formulate a modified MC@NLO-matching prescription that reduces the number of negative-weight events with respect to that stemming from the standard MC@NLO procedure. As a first practical application of such a prescription, that we dub MC@NLO-∆, we have impl
Under the influence of EU law and the ECHR, proportionality has developed into a central feature of contemporary European administrative law, on both the national and the Union level. The article examines this development with respect to the three EU Member States of Denmark, Finland and Sweden. These Nordic legal systems share certain fundamental conceptions of law, such as the limited importance
Objective: To investigate the statistical power of plasma, imaging, and cognition biomarkers as Alzheimer’s disease (AD) clinical trial outcome measures. Methods: Plasma neurofilament light, structural magnetic resonance imaging, and cognition were measured longitudinally in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) in control (amyloid PET or CSF Aβ42 negative [Aβ-] with Clinical Deme
Paperboard has been the basis for packaging materials used to aseptically store and protect food and beverages for a long time. To ensure that there are no bacteria that can spoil the product, sterilizing treatments are made. One such treatment is the retorting process, which involves heating to high temperatures in a pressurized environment of water vapor and dry air. The porous nature of paper m
Background Genome-wide association studies have identified >1000 genetic variants cross-sectionally associated with blood pressure variation and prevalent hypertension. These discoveries might aid the early identification of subpopulations at risk of developing hypertension or provide targets for drug development, amongst other applications. The aim of the present study was to analyze the associat
The erection process of in situ cast concrete frameworks in multi-storey housing consists of multiple on site activities in which labour, equipment and materials are interacting in a complex system. Studies have shown that the current process involves a wide range of non-value adding activities, resulting in poor process efficiency. This paper presents a model developed for discrete-event simulati
Malaria is a public health problem which affects developing countries world-wide. Inadequate skilled lab technicians in remote areas of developing countries result in untimely diagnosis of malaria parasites making it hard for effective control of the disease in highly endemic areas. The development of remote systems that can provide fast, accurate and timely diagnosis is thus a necessary innovatio
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Most signals detected by genome-wide association studies map to non-coding sequence and their tissue-specific effects influence transcriptional regulation. However, key tissues and cell-types required for functional inference are absent from large-scale resources. Here we explore the relationship between genetic variants influencing predisposition to type 2 diabetes (T2D) and related glycemic trai
There is little doubt that genes can spread across unrelated prokaryotes, eukaryotes and even between these domains. It is expected that organisms inhabiting a common niche may exchange their genes even more often due to their physical proximity and similar demands. One such niche is anaerobic or microaerophilic environments in some sediments and intestines of animals. Indeed, enzymes advantageous
Bacteria and fungi, representing two major soil microorganism groups, play an important role in global nutrient biogeochemistry. Biogeographic patterns of bacterial and fungal biomass are of fundamental importance for mechanistically understanding nutrient cycling. We synthesized 1323 data points of phospholipid fatty acid-derived fungal biomass C (FBC), bacterial biomass C (BBC), and fungi:bacter
Multifocal plane microscopy allows for capturing images at different focal planes simultaneously. Using a proprietary prism which splits the emitted light into paths of different lengths, images at 8 different focal depths were obtained, covering a volume of 50x50x4 μm3. The position of single emitters was retrieved using a phasor-based approach across the different imaging planes, with better tha
