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Mutations in the Aristaless related homeobox (ARX) gene are associated with a broad spectrum of disorders, including nonsyndromic X-linked mental retardation, sometimes associated with epilepsy, as well as syndromic forms with brain abnormalities and abnormal genitalia. Furthermore, ARX mutations have been described in a few patients with autism or autistic features. In this study, we screened the
The aim of this work was to characterize the effect of experimental diabetes on neurotransmission in rat vagina. Female Sprague-Dawley rats were divided into two groups: non-diabetic controls (NDM, n=38) and diabetics (DM, n=38). DM was produced by intraperitoneal injection of streptozotocin. Eight weeks later the animals were killed, the distal part of the vagina was removed, and smooth muscle st
The deformation of round tensile bars subject to dynamic loading is studied numerically using two different plasticity theories: J(2)-flow theory and J(2)-deformation theory. Time development of neck localization is visualized and a comparison of the necking patterns obtained using the two different constitutive models is presented. The possibility of using J(2)-deformation theory as an alternativ
The selectivity of mycobionts and cyanobionts in lichen symbioses were examined. We analyzed symbiotic cyanobionts, collected from different sample sites, and compared them to free-living cyanobacteria Nostoc. Cyanobionts were obtained from lichens assigned to the genera Pseudocyphellaria and Sticta, in particular. Multiple gene loci were screened and direct optimization was used in the phylogenet
Purpose: To evaluate the short-term feasibility, efficacy, and safety of a modular bifurcated stent-graft with an internal iliac artery (IIA) side branch for endovascular repair of aortoiliac aneurysms. Methods: Between 2002 and 2005, 10 male patients (median age 75 years, range 59–83) were treated with a bifurcated stent-graft that included a unilateral side branch for the IIA. The median diamet
An excited well-deformed rotational band has been observed in the N = Z odd-odd nucleus Cu-58. The first excited state in this band decays via gamma emission to the spherical states associated with the first minimum in the potential, thus providing for its unambiguous assignment to Cu-58. I, contrast, its bandhead decays via emission of a prompt 2.4(1) MeV proton to an excited state in the daughte
BACKGROUND Previous studies have relied predominantly on the body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) to assess the association of adiposity with the risk of death, but few have examined whether the distribution of body fat contributes to the prediction of death. METHODS We examined the association of BMI, waist circumference, and waist-to-hip ra
The microfungal communities of a mire in northern Sweden were studied. Three plant communities were sampled at two depths, one dry ombrotrophic, one wet ombrotrophic, and one wet minerotrophic site. The fungi were isolated on malt agar using the dilution-plate technique. The most commonly isolated species were Chaunopychnis alba, Mortierella isabellina, Mortierella pulchella, Mycelium radicis atro
BACKGROUND: The purpose of this study was to evaluate the ultrasound technique for measuring subcutaneous adipose tissue in infants. METHODS: Twenty infants were investigated at 3, 6, and 12 months of age. All measurements were made by the same investigator in triplicate on the left side of the body at the triceps and subscapular anatomic landmarks and at the abdomen and thigh. An ultrasound syste
In the 20 years since the discovery of Helicobacter pylori the number of formally described Helicobacter spp. has increased dramatically. The majority of species in the genus have been associated with some form of pathology. Similar to other Gram-negative bacteria, all helicobacters have lipopolysaccharides or endotoxins in the outer leaflet of their outer membrane which is an important modulator
We prove under quite general assumptions the existence of a bounded positive solution to the semilinear Schrodinger equation in a two-dimensional exterior domain.
We have developed an optical technique called ballistic imaging to view breakup of the near-field of an atomizing spray. In this paper, we describe the successful use of a time-gated ballistic imaging instrument to obtain single-shot images of core region breakup in a transient, single hole atomizing diesel fuel spray issuing into one atmosphere. We present a sequence of images taken at the nozzle
During the latest several decades, there has been considerable interest in revealing the relationship between El Nino-southern oscillation (ENSO) and hydro-meteorological variables. The oscillation is characterized by a simple index, the southern oscillation index (SOI). However, thus far, there is little evidence for the influence of ENSO in Korea and Japan. The influence of ENSO has also been st
A sediment core from a lake in the Kap Farvel area on South Greenland was analysed with respect to pollen and microfossil content, loss-on-ignition, magnetic susceptibility and radiocarbon age. The aim was to reconstruct the limnic arid terrestrial changes taking place at the Pleistocene-Holocene boundary. Organic sedimentation started between 12 200 and 12 800 cal yr B.P. Break-up of sea-ice arou
Individual attitudes to distributions of life years between two groups in a society are explored by means of an experiment. Subjects are asked to place themselves behind a veil of ignorance which is specified in terms of risk (known probabilities) for some subjects and in terms of uncertainty (unknown probabilities) for some subjects. The latter is argued to be the appropriate interpretation of Ra
5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid are important intermediate metabolites in the formation of cutaneous melanin pigment. Since they both are serious candidates as markers of melanoma progression, their stability in urine has been investigated during storage at various conditions. The results show that storage at -20 degrees C is necessary. Both compounds are nonstabl
The growth arrest-specific gene 6 (Gas6) plays a role in pro-atherogenic processes such as endothelial and leukocyte activation, smooth muscle cell migration and thrombosis, but its role in atherosclerosis remains uninvestigated. Here, we report that Gas6 is expressed in all stages of human and mouse atherosclerosis, in plaque endothelial cells, smooth muscle cells and macrophages. Gas6 expression
