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As shown by transgenic mouse models and by using phosphodiesterase 3 (PDE3) inhibitors, PDE3B has an important role in the regulation of insulin secretion in pancreatic β-cells. However, very little is known about the regulation of the enzyme. Here, we show that PDE3B is activated in response to high glucose, insulin and cAMP elevation in rat pancreatic islets and INS-1 (832/13) cells. Activation

The growth rate of atmospheric carbon dioxide (CO2) concentrations since industrialization is characterized by large interannual variability, mostly resulting from variability in CO2 uptake by terrestrial ecosystems (typically termed carbon sink). However, the contributions of regional ecosystems to that variability are not well known. Using an ensemble of ecosystem and land-surface models and an

The aim of the current study was to provide updated time-path equations for risk factors of type-2-diabetes-related cardiovascular complications for application in risk calculators and health economic models. Observational data from the Swedish National Diabetes Register were analysed using Generalized Method of Moments estimation for dynamic panel models (N = 5,043, aged 25-70 years at diagnosis

World Health Organization (WHO) has in 2013 changed the diagnostic criteria for gestational diabetes mellitus (GDM) to acknowledge the putative importance of mildly elevated fasting plasma glucose (FPG) levels on pregnancy outcomes. We aimed to determine the prevalence and risk factors of GDM using the previous WHO 1999 versus WHO 2013 criteria in North India.

The clinical presentation of type 1 diabetes is preceded by a prodrome of beta cell autoimmunity. We probed the short period of subtle metabolic abnormalities, which precede the acute onset of diabetes in the spontaneously diabetic BB rat, by analyzing the serum metabolite profile detected with combined gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS

In this paper, survey data from 60 demonstrations in 8 European countries is analyzed, to explore whether social class matters in political protest. Do different types of demonstrations mobilize different groups of employees/workers? And do social class matter for demonstrators’ attitudes about social inequality, welfare privatization and political trust—or do national context and/or the issue of

Abstract Digital visualization has gone through a revolutionary decade. Compared to other fields where these methods have been applied, archaeology has been, and still is, more resistant to integrating tools and instruments able to describe materials and scenarios with high resolution. This is partly due to the archaeological misconception of high cost of scientific equipment and the complexity in

Call for Papers: Special Issue of Energy Efficiency “Demand-side policies, governance and socio-technical mitigation pathways of limiting global warming to 1.5°C” Full Submission Deadline: 1st November 2017 The journal Energy Efficiency covers wide-ranging aspects of energy efficiency in the residential, tertiary, industrial and transport sectors. Coverage includes a number of different topics and

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/call_for_papers_si_ds_1.5c.pdf - 2026-07-10

Is the circular economy ambitious enough? A look at incorporating PSS (product-service systems) into China’s leapfrog development strategy Author: Jennifer Hinton hintojen@yahoo.com Thesis supervisor: Dr. Oksana Mont International Institute for Industrial Environmental Economics Lund University A Thesis Submitted to Lunds Universitet in partial fulfilment of the requirements for the degree of Mast

https://www.lumes.lu.se/sites/lumes.lu.se/files/jennifer_hinton.pdf - 2026-07-10

Teaching Academy application Lisa Flower 1 Interactional and emotional learning: Evolving a teaching philosophy I stand behind the lectern, looking down far-too-frequently at my far-too-detailed notes whilst clicking maniacally through my far-too-crowded PowerPoint, racing through the slides and leaving no time or opportunity for questions. My heart is racing, my palms are sweating and my stress l

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2023-05/Lisa%20Flower%20-%20Teaching%20academy%20application%202022_utan%20bilagor.pdf - 2026-07-10

This thesis explores contradictions, inadequacies, and competing formulations within Giovanni Arrighi’s theory of systemic cycles of accumulation (SCAs) as a Kuhnian scientific paradigm. This has been carried out through a comparative study on how the theory has been applied by scholars on the issue of the prospective hegemonic rise of China in the contemporary setting. The study finds that there

The sectarian civil war in Syria is one of the most entrenched civil wars in contemporary time and has proven hard to resolute, despite various attempts by international actors. A power-sharing system of consociationalism has often been proposed, given its ability to divide the power between sectarian groups and allocate stability within a political system. Through discourse analysis, this thesis

Tourism is one of the fastest-growing economic sectors in the world. Due to that, many developing world’s regions with limited economic activity adapt tourism as a development strategy. The point of departure is a critical consideration why tourism, while producing such immense economic benefits, frequently also perpetuates already existing socio-economic, cultural, and environmental dysfunctions.

Research Problem and Objectives: Bangladesh is one of the most vulnerable countries in the world to climate change. Over the last years, scholars have discussed that climate change has disproportionate impacts on people as the result of their social, political and economic conditions. Such an argument has led to the inclusion of gender in the climate change debate. However, gender in the climate c

The purpose of this thesis is to examine how the Icelandic state perceives the Arctic and its place in that region of the world. The thesis sees Iceland’s state identity as narratively performed and engages with a three-dimensional view of state identity based on space, time, and the state’s relationship with Others to construct a holistic view of state identity. Through a narrative analysis of Ic

As climate change continues to threaten us more and more, different ways of governing climate change are considered. Multi-level governance approach is widely used in the literature to examine how global, national, and local actor interacts and influence each other. In this thesis I analyse how multi-level governance of climate change work in the case of Istanbul by adopting a powerbased approach.

Over the last years, concerns have been expressed by the media and scientific literature about baile funk and Brazilian funk in general. Brazilian funk is a rebellious Brazilian music style which rose from the favelas from the 1980s onwards. Baile funk refers to funk dance parties which have a violent and aggressively sexualized nature. It is regarded as an expressive cultural phenomenon and it is