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As alterations in tissue pH underlie many pathological processes, the capability to image tissue pH in the clinic could offer new ways of detecting disease and response to treatment. Dynamic nuclear polarization is an emerging technique for substantially increasing the sensitivity of magnetic resonance imaging experiments. Here we show that tissue pH can be imaged in vivo from the ratio of the sig

Some scenarios for planetesimal formation go through a phase of collapse of gravitationally bound clouds of millimeter- to centimeter-size pebbles. Such clouds can form, for example, through the streaming instability in protoplanetary disks. We model the collapse process with a statistical model to obtain the internal structure of planetesimals with solid radii between 10 and 1000 km. During the c

This article presents a study related to application of pre-chamber ignition system in heavy duty natural gas engine which, as previously shown by the authors, can extend the limit of fuel-lean combustion and hence improve fuel efficiency and reduce emissions. A previous study about the effect of pre-chamber volume and nozzle diameter on a single cylinder 2 liter truck-size engine resulted in reco

Control applications contain both logic, sequencing, and control algorithms. A holistic view of this is seldom presented in teaching and papers. One reason is the separation of communities -- automation groups typically come from the Programmable Logic Controller (PLC) world while control engineers primarily come from the Distributed Control System (DCS) world. Both logic, sequencing, and control

We report on our studies of the neutron-skin effects in high-pT observables at the LHC. We study the impact of the neutron-skin effect on the centrality dependence of inclusive direct photon, highpT hadron and W± production in nuclear collisions at the LHC. The neutron-skin effect refers to the observation that in spherical heavy nuclei, the tail of the neutron distribution extends farther than th

Forest degradation, forest fires, and wildlife poaching have devastated biodiversity in Indonesia. To assess the impact of forest degradation and the potential for recovery, we used birds as a proxy for biodiversity and assessed density estimates (hereafter density) in the degraded lowland forest of Harapan Rainforest Ecosystem Restoration Concession (HRF) in Sumatra. In this study, a total of 149

A negative association between interval length and infant and child mortality has been consistently identified in modern developing countries. The reasons for this association are unclear, however. Leading hypotheses explain these differences as a result of sibling competition, maternal depletion, infection transmission, or unobserved maternal factors, but none has received overwhelming support.

During the last decade Trump International Golf Links Scotland (TIGLS) has built on land where no development was previously outlined and, appropriating parts of a Site of Special Scientific Interest, has come to occupy an important place in debates on Scottish planning policy. Though plans were initially rejected in 2007 by the Aberdeenshire planning body responsible, the Scottish Government subs

Many animals are known to preferentially mate with partners that are dissimilar at the major histocompatibility complex (MHC) in order to maximize the antigen binding repertoire (or disease resistance) in their offspring. Although several mammals, fish or lizards use odour cues to assessMHCsimilarity with potential partners, the ability of birds to assessMHC similarity using olfactory cues has not

C2C12 cells exposed to hyperthermia (41 degrees C) experienced an increase in both protein synthesis and degradation. The addition of IL15 under hyperthermic conditions resulted in an important increase in protein synthesis with no changes in protein degradation, except when cells overexpressed PPARdelta. The PPARdelta agonist GW501516 exerted similar effects on protein synthesis to IL15. Expressi

Previous work on protoplanetary dust growth shows a halt at centimeter sizes owing to the occurrence of bouncing at velocities of 0.1 m s-1 and fragmentation at velocities ≳;1 m s-1. To overcome these barriers, spatial concentration of centimeter-sized dust pebbles and subsequent gravitational collapse have been proposed. However, numerical investigations have shown that dust aggregates may underg

Innovations in the lighting sector, such as LED-based light sources, have opened up unprecedented possibilities to both save energy and improve the quality of lighting. There is growing evidence of light's importance for human health, moods, work productivity and quality of life in general; but the uptake of new solutions is still rather slow in society. The public sector can play an important rol

We have experimentally studied the conditions for acoustic particle focusing inside aqueous droplets in two-phase-systems, and confirmed our findings by theoretical analysis. The results show that the acoustic properties of the two fluids have to be matched to achieve strong acoustic resonance and focusing in the system.

The placenta and tumors share important characteristics, including a requirement to establish effective angiogenesis. In the case of the placenta, optimal angiogenesis is required to sustain the blood flow required to maintain a successful pregnancy, whereas in tumors establishing new blood supplies is considered a key step in supporting metastases. Therefore the development of novel angiogenesis

Mesoscopic simulations with two-dimensional (2D) models have been performed to elucidate the dynamics of deformable red blood cells (RBCs) in deterministic lateral displacement (DLD) devices. Several shapes of posts, including circular, diamond, square and triangular structures and RBCs with different rigidities are considered. In comparison to rigid particles, the deformable RBCs exhibit much mor