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Accrual rate-limiting factors in a Swedish randomised ductal carcinoma in situ (DCIS) trial - a demographic study

In the last two decades the introduction of mammographic screening in the Western world has increased the number of diagnosed ductal carcinomas in situ (DCIS) considerably. In situ carcinoma of the breast is considered a heterogeneous disease, the natural history of which is not well known. Thus, appropriate treatment needs to be established. For this reason, a randomised trial studying the effect

Modified General Primer PCR System for Sensitive Detection of Multiple Types of Oncogenic Human Papillomavirus

Human papillomavirus (HPV) infection is a necessary cause of cervical cancer and cervical dysplasia. Accurate and sensitive genotyping of multiple oncogenic HPVs is essential for a multitude of both clinical and research uses. We developed a modified general primer (MGP) PCR system with five forward and five reverse consensus primers. The MGP system was compared to the classical HPV general primer

On the interaction between beta 2-microglobulin and group A streptococci

beta 2-microglobulin (beta 2m) was found to interact with many group A streptococcal strains. The interaction appeared to require multipoint attachment, since monomeric beta 2m in solution showed no binding, whereas both beta 2m monomers bound to liposomes, and beta 2m in aggregates showed affinity for the bacteria. Aggregated HLA antigens (-A, -B and -C) and aggregated beta 2m exhibited the same

Conflict of legal norms: definition and varieties

As emphasized by Jeremy Bentham and the analytical school, logical consistency is a requirement for rational legislation. For understanding consistency between norms, a logical scrutiny of normative conflicts is needed. In our paper, a framework for the fine structure of such conflicts is introduced and explained. “Normative conflict” is defined relative the framework and different types of confli

Vertical Trade

Popular Abstract in Swedish Avhandlingen består av tre separata papper. De är alla empiriska studier som undersöker hur fragmentering av produktionsprocesser och globala utbudskedjor har påverkat internationell handel. Den första studien fokuserar på hur privata standarder i den alltmer globaliserade livsmedelsindustrin påverkar företags importbeteende. Genom att ge en kvalitetsförsäkran kan certThis thesis consists of three separate papers. They are all empirical papers that examine how fragmentation of production processes and global value chains have affected international trade patterns. The first paper focuses on how private standards in the increasingly geographically fragmented food sector affect firm-import behaviour. By providing a quality insurance for the imported good, certif

Molecular characterization of invasive and non-invasive Streptococcus pyogenes isolates from Romania.

In 2002, the Romanian National Reference Laboratory was invited to join the Strep-EURO project to study invasive Streptococcus pyogenes infections. During 2003 and 2004, a total of 33 isolates recovered from invasive disease were received from eight Romanian counties. For comparison, 102 isolates from non-invasive disease, as well as a collection of 12 old invasive strains (isolated between 1967 a

Co-Exploring Everyday Life of Adults with ADHD

There are relatively few studies based on an individual adult perspective on ADHD which takes into account how various factors interact and affect everyday life. Compensatory strategies can facilitate life for people with ADHD and those strategies might include the use of assistive technology or cognitive support. The purpose of this paper is to present and discuss how various factors can facilita

Towards GLUE 2: Evolution of the Computing Element Information Model

A key advantage of Grid systems is the ability to share heterogeneous resources and services between traditional administrative and organizational domains. This ability enables virtual pools of resources to be created and assigned to groups of users. Resource awareness, the capability of users or user agents to have knowledge about the existence and state of resources, is required in order utilize