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CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa.

The recruitment of antigen-specific T lymphocytes to the intestinal mucosa is central to the development of an effective mucosal immune response, yet the mechanism by which this process occurs remains to be fully defined. Here we show that the CC chemokine receptor 9 (CCR9) is selectively and functionally expressed on murine alpha(E)beta(7)(+) naive CD8alphabeta(+) lymphocytes and a subset of rece

Drought legacy affects microbial community trait distributions related to moisture along a savanna‐grassland precipitation gradient

Ecosystem models commonly use stable‐state assumptions to predict responses of soil microbial functions to environmental change. However, past climatic conditions can shape microbial functional responses resulting in a ‘legacy effect’. For instance, exposure to drier conditions in the field may shape how soil microbial communities respond to subsequent drought and drying and rewetting (DRW) event

Human experimental exposure to glyphosate and biomonitoring of young Swedish adults

Glyphosate (GLY), N-(phosphonomethyl) glycine, is the most widely used herbicide in the world. It is a broad-spectrum herbicide, also used in crop desiccation. Agricultural workers may be occupationally exposed and general populations may be exposed to GLY mainly through diet. We studied the kinetics of GLY by measuring the parent compound and its metabolite aminomethylphosphonic acid (AMPA) in ur

The Health of Older Family Caregivers–A 6-Year Follow-up

It is unclear whether caregiving has an impact on the physical, mental and functional health of older caregivers. This study aimed to describe physical, mental and functional health in relation to family caregiving in old age (60+) over a six-year period. The study comprised 2,294 randomly selected individuals (60–96 years) from the Swedish National Study on Aging and Care, who answered the questi

Central Asian Law: Legal Cultures, Governance and Business Environment in Central Asia. A Collection of Papers from Central Asian Guest Researchers Seconded to Lund University

This research report is a compilation of essays written by guest researchers from Central Asia who spent four to twelve months at the Department of Sociology of Law, Lund University, and conducted research on various topics pertaining to legal cultures, governance and business environments in Central Asia. These guest research stays (secondments) took place in the framework of the EU-funded projec

The Being Taken Seriously Questionnaire—Development and Psychometric Evaluation of a PREM Measure for Person-Centeredness in a High-Tech Hospital Environment

There is a need for patient-reported experience measures (PREMs) in high-tech hospital environments based on the philosophy of person-centeredness. The aim of this study was to describe the development and initial psychometric evaluation of a measure of person-centeredness by means of being taking seriously. In this cross-sectional survey, the study sample (n = 79) completed two measures, the Bein

The importance of a β-glucan receptor in the nonopsonic entry of nontypeable Haemophilus influenzae into human monocytic and epithelial cells

Previous reports showed that nontypeable Haemophilus influenzae (NTHi) reside in macrophage-like cells in human adenoid tissue. This study investigated the ability of nonopsonized NTHi and encapsulated H. influenzae type b (Hib) to enter human monocytic and epithelial cells. The number of intracellular bacteria was determined by a viability assay and flow cytometry. To characterize the mechanisms

On the Formation of Necks at Crack Tips under Plane Stress Conditions.

The conditions for necking are well defined through the theory of Hill [1]. These conditions are applied to elasto plastic linearly hardening Tresca.and v Mises materials for different hardening characteristics. The results suggest that necking developes for all hardening materials. Below a certain hardening the stresses normal to the necking region and just outside it decrease during the necking

Wiki collaboration in organizations: an exploratory study

The use of social media technologies in organizations has introduced novel ways of collaboration, communication, and knowledge sharing. In this respect, the present study is concerned with examining the use of one type of social media, the wiki technology, by members of several professional communities of practice to collaborate and share knowledge with each other. As such, it seeks to identify an

Spatial and Temporal Analysis of Fires Detected by MODIS Data in Northern Iran From 2001 to 2008

Fire, a natural disaster, has significant effects on ecosystems and plays a major role in deforestation, and it is a major source of trace gases, aerosols and carbon fluxes. Remote sensing is a valuable data source to investigate different phases of fire management. The Moderate Resolution Imaging Spectroradiometer (MODIS) has been designed to include specific characteristics for fire detection. I

Gabor wavelet networks for object representation

In this article we want to introduce first the Gabor wavelet network as a model based approach for an effective and efficient object representation. The Gabor wavelet network has several advantages such as invariance to some degree with respect to translation, rotation and dilation. Furthermore, the use of Gabor filters ensured that geometrical and textural object features are encoded. The feasibi

Nuclear magnetic resonance relaxation in micelles : Deuterium relaxation at three field strengths of three positions on the alkyl chain of sodium dodecyl sulphate

A 2H n.m.r. relaxation study of sodium dodecyl sulphate (SDS) in the micellar phase is presented. The surfactant is specifically deuterated in the α-, γ- and ω-positions. Relaxation data are obtained at two temperatures and at three field strengths, and show a dependence on the field strength. The data are analysed with the 'two-step' model of relaxation, and the fast correlation times as well as

Loss of Canonical Notch Signaling Affects Multiple Steps in NK Cell Development in Mice

Within the hematopoietic system, the Notch pathway is critical for promoting thymic T cell development and suppressing the B and myeloid lineage fates; however, its impact on NK lymphopoiesis is less understood. To study the role of Notch during NK cell development in vivo, we investigated different NK cell compartments and function in Rbp-Jkfl/flVav-Cretg/+ mice, in which Rbp-Jk, the major transc

Biphasic Expression of the Fos and Jun Families of Transcription Factors Following Transient Forebrain Ischaemia in the Rat. Effect of Hypothermia

Transient global ischaemia induces the expression of immediate early genes. Using in situ hybridization, the expression of c‐fos, fosB, fra‐1, fra‐2, c‐jun and junB was studied after 15 min of normothermic and hypothermia (33°C) transient forebrain ischaemia in the rat, induced by common carotid occlusion combined with systemic hypotension. Two phases of induction of the immediate early genes were