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Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors

In addition to acting as a physical barrier against microorganisms, the skin produces antimicrobial peptides and proteins. After wounding, growth factors are produced to stimulate the regeneration of tissue. The growth factor response ceases after regeneration of the tissue, when the physical barrier protecting against microbial infections is re-established. We found that the growth factors import

High prevalence of Helicobacter Species detected in laboratory mouse strains by multiplex PCR-denaturing gradient gel electrophoresis and pyrosequencing.

Rodent models have been developed to study the pathogenesis of diseases caused by Helicobacter pylori, as well as by other gastric and intestinal Helicobacter spp., but some murine enteric Helicobacter spp. cause hepatobiliary and intestinal tract diseases in specific inbred strains of laboratory mice. To identify these murine Helicobacter spp., we developed an assay based on PCR-denaturing gradie

Mortality among elderly receiving long-term care: a longitudinal cohort study.

Backgrounds and aims: To investigate mortality, determinants of mortality, and time until death among elderly subjects receiving public long-term care. Methods: This study comprises 626 respondents (age: 65-98 years). Data were collected for two cohorts (2001 and 2002). Cox regression analysis was used to identify determinants of mortality. Those who died and those who did not die were compared by

Albumin-induced coagulopathy is less severe and more effectively reversed with fibrinogen concentrate than is synthetic colloid-induced coagulopathy.

Background. Synthetic colloids cause dilutional coagulopathy. The aims of our study were to determine whether the natural colloid albumin induces a lesser degree of coagulopathy compared to synthetic colloids, and the comparative effectiveness of fibrinogen concentrate to reverse coagulopathy following dilution with these solutions. Methods. Coagulation was assessed with rotational thrombelastomet

Finger jointing of freshly sawn Norway Spruce side boards : a comparative study of fracture properties of joints glued with phenol-resorcinol and one-component polyurethane adhesive

Finger jointing of unseasoned Norway Spruce was studied with respect to tensile strength, adhesive penetration and durability. Finger joints were manufactured with 1) unseasoned wood and one component polyurethane (PUR) adhesive, 2) dried wood and PUR adhesive and 3) dried wood and phenol resorcinol formaldehyde (PRF) adhesive. Two levels of wood density were used. The tensile strength of the f

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease

Recent studies suggest a variety of factors characterize substantia nigra neurons vulnerable to Parkinson's disease, including the transcription factors pituitary homeobox 3 (Pitx3) and orthodenticle homeobox 2 (Otx2) and the trophic factor receptor deleted in colorectal cancer (DCC), but there is limited information on their expression and localization in adult humans. Pitx3, Otx2, and DCC were i

Al adjuvants can be tracked in viable cells by lumogallion staining.

The mechanism behind the adjuvant effect of aluminum salts is poorly understood notwithstanding that aluminum salts have been used for decades in clinical vaccines. In an aqueous environment and at a nearly neutral pH, the aluminum salts form particulate aggregates, and one plausible explanation of the lack of information regarding the mechanisms could be the absence of an efficient method of trac

Increased Risk of Transmission of Hepatitis C in Open Heart Surgery Compared With Vascular and Pulmonary Surgery

Background. We report a case of patient-to-surgeon transmission of hepatitis C virus (HCV), and the subsequent transmission of HCV to surgical patients. Methods. In 2007, a cardiac surgeon tested positive for hepatitis C. A complete look-back investigation was initiated that involved screening of all patients on the surgeon's operating lists between September 2004 and April 2007. Genotyping and ph

Quality of life and client satisfaction as outcomes of the Redesigning Daily Occupations (ReDO) programme for women with stress-related disorders: A comparative study.

OBJECTIVE: The outcomes, in terms of quality of life and satisfaction with rehabilitation, of the 16-week Redesigning Daily Occupations (ReDO) programme as a work rehabilitation method for women with stress-related disorders was evaluated. It was hypothesised that, compared to women who got Care as Usual (CAU), the ReDO group would improve their quality of life and self-mastery more, and that thos

Shell structure of weakly-bound and resonant neutrons

The systematic change of shell structure in both weakly bound and resonant neutron one-particle levels in nuclei towards the neutron drip line is exhibited, solving the coupled equations derived from the Schrodinger equation in coordinate space with the correct asymptotic behaviour of wave functions for r -> infinity. The change comes from the behaviour unique in the one-particle motion with low o

The first national pressure ulcer prevalence survey in county council and municipality settings in Sweden.

Aim: To report data from the first national pressure ulcer prevalence survey in Sweden on prevalence, pressure ulcer categories, locations and preventive interventions for persons at risk for developing pressure ulcers. Methods: A cross-sectional research design was used in a total sample of 35 058 persons in hospitals and nursing homes. The methodology used was that recommended by the Europea

Fibrinogen and FXIII dose response effects on albumin-induced coagulopathy.

Objectives. Natural colloid albumin induces a lesser degree of dilutional coagulopathy than synthetic colloids. Fibrinogen concentrate has emerged as a promising strategy to treat coagulopathy, and factor XIII (FXIII) works synergistically with fibrinogen to correct coagulopathy following haemodilution with crystalloids. Our objectives were to examine the ability of fibrinogen and FXIII concentrat

Psychiatric rehabilitation in community-based day centres: Motivation and satisfaction.

Abstract Objective: This study investigated attendees' motivation and motives for participation in day centres and their satisfaction with the rehabilitation, while also addressing the influence of day centre orientation (work- or meeting-place orientation), gender and age. Methods: Ninety-three Swedish day centre attendees participated in a cross-sectional study and completed questionnaires about

Interactions of phytate and myo-inositol phosphate esters (IP1-5) including IP5 isomers with dietary protein and iron and inhibition of pepsin

Phytic acid (IP6) and myo-inositol phosphate esters (IP1-5), including IP5 isomers prepared chemically and enzymatically with bacterial and fungal phytases, were examined for their effects on protein aggregation of soy protein and beta-casein, interaction with Fe3+, and pepsin activity. The results indicated that the aggregating capabilities of IP esters (IP1-6) on the 2 proteins decreased dramati

Terapi, upplysning, kamp och likhet till varje pris - undervisningsideologier och diskurser hos lärare och lärarstuderande i musik

This study is the second part of a larger work with the purpose to distinguish, describe and discuss the discourses around music education in school. The first part focused on how adolescents in secondary school talk abot music education, and the second part is concerned with teaching ideologies and discources among teachers and teacher education students. An overarching purpose of the two studies