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Background: Celiac disease is associated with HLA-risk haplotypes, but non-HLA genes and environmental factors are also linked to disease susceptibility. In this study, we explore the molecular pathways involved in celiac disease by analyzing the differential expression of genes in both the gut and peripheral blood across various celiac disease phenotypes. Methods: Whole genome RNA sequencing was

Introduction: Tpeak-Tend interval (Tpe) is considered to be an ECG reflection of the dispersion of repolarization (DOR), and as such has been proposed as a predictor of arrhythmias. In ischemia, robustness of the Tpe-DOR relationship may suffer from variability of the myocardium at risk (MaR) area. In the present study, we evaluated the contribution of DOR and MaR to single‑lead and multi‑lead Tpe

Aims: Stratifying renal damage in type 2 diabetes is challenging due to overlapping features between diabetic nephropathy (DN) and non-diabetic renal disease (NDRD). While miR-27b-3p modulates kidney fibrosis in DN through the lysine63 ubiquitination pathway, its upstream regulation and diagnostic relevance remain unclear. Methods: In a biopsy-verified cohort of 231 chronic kidney disease (CKD) pa

BioMed CentralBMC Biotechnology ss Open AcceResearch article Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants Troels T Nielsen1,2, Johan Jakobsson1, Nina Rosenqvist1 and Cecilia Lundberg*1 Address: 1CNS Gene Therapy Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Sciences, Lund University, BMC A11, S-221 84 Lund,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_bmc_biotechnology.pdf - 2026-06-28

The purpose of this study is to critically research and describe how the leaders of the National Association of Evangelicals and within the campaign ‘Evangelical Climate Initiative’ seek to influence climate change policymaking in the United States. The importance of this study is coming from the need to assess how strongly a religious group influences climate change policymaking in the United Sta

The aim of this thesis was to explore the effects of climate change and the resilience efforts in Greenland by utilizing the resilient framework as suggested by Becker (2014). There was a focus at the official governmental level. Semi-structured interviews were carried out with informants from different departments within the Greenland Government. Government documents were also analyzed. The resul

UGS can provide extensive health benefits for city dwellers, especially those with close availability. However, previous research in the US has shown that UGS are not equally distributed within the city. This paper uses an urban justice approach to examine the distribution of UGS in Malmö, Sweden. Following a spatial analysis linking availability of UGS to socio-economic variables using ArcGIS, th

This essay investigates the communicative elements video games in the RPG genre utilise in order to convey emotion through narrative, and the difference between older and newer games. The essay focuses on the execution and interplay of verbal and non-verbal communication of the linguistic and semiotic examined in four video games chosen from the Final Fantasy series. It quantitatively compares emp

This thesis investigates how business angel investors interpret and evaluate hybrid entrepreneurial teams, startups led by founders who retain salaried employment while launching their ventures. While hybrid entrepreneurship is increasingly common, it challenges traditional heuristics around founder commitment, team scalability, and investability in early-stage finance. Drawing on ten qualitative

Transitions in life and CBT in nursing 4 ECTS Preliminary program 29.01.2017 Transitions in life and CBT in nursing ©Jóhanna Bernhardsdóttir, Hildur Sigurdardóttir The course introduction: This is a Nordplus course on Cognitive behavior therapy in nursing focusing on transitions in life throughout the life-span. The course is provided at the Faculty of Nursing, University of Iceland May 15-19, 201

https://www.student.med.lu.se/sites/student.med.lu.se/files/nordsne-course-decription-2017.pdf - 2026-06-28

Most deterioration processes in cement based materials are closely related to moisture sorption and moisture transport properties. Therefore, it is important to study these properties, both theoretically and practically. This work is an experimental investigation in this field. Nowadays, the cement industry produces cements with increasing amounts of supplementary cementitious materials (SCMs) to

The relation between information science and library science has been debated for decades, and even attempts at utilizing methods generally acknowledged as robust for the purpose of mapping research fields have yielded results with large variations. Therefore, a set of citation analyses was performed, comparing the results of analyses on information science and library science separately but also

Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic consequences independent of overall adiposity. WHR is heritable, but few genetic variants influencing this trait have been identified. We conducted a meta-analysis of 32 genome-wide association studies for WHR adjusted for body mass index (comprising up to 77,167 participants), following up 16 loci in an addit

Safety performance functions are frequently used to describe the relation of various factors to the number of accidents, often focusing on exposure of vulnerable road users. Those studies require reliable data regarding exposure, but collecting such data is resource demanding, often resulting in short observational periods. This might produce measurement errors, influencing the reliability of the

Background: Severe traumatic knee injury, including injury to the anterior cruciate ligament (ACL), leads to impaired sensorimotor function. Although improvements are achieved by training, impairment often persists. Because good sensorimotor function is associated with better patient-reported function and a potential lower risk of future joint problems, more effective treatment is warranted. Tempo

Patterns of genetic diversity have previously been shown to mirror geography on a global scale and within continents and individual countries. Using genome-wide SNP data on 5174 Swedes with extensive geographical coverage, we analyzed the genetic structure of the Swedish population. We observed strong differences between the far northern counties and the remaining counties. The population of Dalar

Background: Risk gene variants for celiac disease, identified in genome-wide linkage and association studies, might influence molecular pathways important for disease development. The aim was to examine expression levels of potential risk genes close to these variants in the small intestine and peripheral blood and also to test if the non-coding variants affect nearby gene expression levels in chi