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Osteoarthritis (OA) of the knee can be defined as primary (non-traumatic) or secondary (post-traumatic). Both non-traumatic OA and post-traumatic OA have been described predominantly in the medial compartment of the knee. The objective of this study was to compare the location of structural radiographic changes in non-traumatic OA and post-traumatic OA. A non-traumatic cohort, consisting of 155 pa

Tumor cells often carry mutations in genes that control cell survival, and become resistant to signals that trigger cell death. Yet, some cell death pathways remain intact in tumor cells. If identified, these pathways might be exploited to selectively remove tumor cells. HAMLET (human α-lactalbumin made lethal to tumor cells) is a protein-lipid complex derived from human milk that activates cell d

In this article it is argued that Scripture is embedded in the Markan text to such an extent that it cannot be removed without destroying the story. The role Scripture plays in the Gospel (and New Testament) is certainly neither a matter of antithesis nor of fulfillment, but rather of a shared symbolic universe. Analysing Mk 7.1-23 textually, effectually and contextually, this article draws attent

The evaluation of the effectiveness of safety installations (such as emergency exits, lighting, etc.) is a key factor to improve the evacuation performance of buildings or transportation systems. In fact, even though an installation is designed to achieve a given design goal, it could happen it does not perform as intended. According to the Theory of Affordances, this could be interpreted in relat

Industrial energy systems involve many components where fluid flow, heat and mass transfer are the important transport processes. For design and development as well as investigation of innovative ideas, computational methods are of vital importance. Since the early pioneering works (by, e.g., the Spalding group) in the 1960s and 1970s, the development has been tremendous and nowadays CFD (computat

In societies with an increasing proportion of elderly active people it is valuable to gain knowledge about what elderly people actually do and want to do in relation to activity arenas in the public environment. The main aim of this study was to investigate elderly people’s preferences and frequencies of visits to public facilities in a Swedish town center. A further aim was to gather information

In this study, we show that distinct compartmentalization patterns of the IL-1 molecules (IL-1alpha and IL-1beta), in the milieu of tumor cells that produce them, differentially affect the malignant process. Active forms of IL-1, namely precursor IL-1alpha (pIL-1alpha), mature IL-1beta (mIL-1beta), and mIL-1beta fused to a signal sequence (ssIL-1beta), were transfected into an established fibrosar

Popular Abstract in Swedish Studien beskriver och analyserar strategisk förändring i tre svenska tidningsföretag. I studien beskrivs hur företagen utvecklades från enaffärs-verksamheter till multiaffärs-verksamheter. Studien pekar på hur denna utveckling framförallt ska ses som resultat av etableringen och spridningen av en ny kunskapsformation. Ett centralt innehåll i den kunskapsformationen var The dissertation examines power and knowledge in strategic changes. It is a study of changes in three Swedish newspaper companies which developed from single-business to multi-business corporations. It is suggested that this transformation was based upon the establishment and reproduction of a new knowledge formation. This knowledge was the knowledge of strategy, particularly the classical perspec

Background: Data commentary, in-text comments on the visual presentation of data, is acknowledged as a central aspect of academic writing in many engineering disciplines. At the same time, it is a feature that it has been shown to be challenging for students. One of the genres in which data commentary plays a significant role in many engineering disciplines is the master’s thesis. Comparatively li

Innate immunity relies on an effective recognition of the pathogenic microorganism as well as on endogenous danger signals. While bacteria in concert with their secreted virulence factors can cause a number of inflammatory reactions, danger signals released at the site of infection may in addition determine the amplitude of such responses and influence the outcome of the disease. Here, we report t

Journal of Thrombosis and Haemostasis Supplement 1(3): abstract 0204. DOI: 10.1111/j.1538-7836.2005.03001.x

Journal of Thrombosis and Haemostasis Supplement 1(3): abstract 1895. DOI: 10.1111/j.1538-7836.2005.03001.x

Monoamines are presumed to be diffuse metabotropic neuromodulators of the topographically and temporally precise ionotropic circuitry which dominates CNS functions. Their malfunction is strongly implicated in motor and cognitive disorders, but their function in behavioral and cognitive processing is scarcely understood. In this paper, the principles of such a monoaminergic function are conceptuali

It is commonly assumed that sex chromosomes evolve recombination suppression because selection favours linkage between sex-determining and sexually antagonistic genes. However, although the role of sexual antagonism during sex chromosome evolution has attained strong support from theory, experimental and observational evidence is rare or equivocal. Here, we highlight alternative, often neglected,