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Background: Copeptin is a reliable surrogate marker for the neurohypophyseal hormone vasopressin. Elevated plasma level of copeptin has been associated with cardiovascular and metabolic disease risk. Objective: To investigate the association between copeptin and risk of dementia. Methods: In all, 18,240 individuals from Malmö, Sweden, were examined between 2002 and 2006 (mean age 69.3 years, 69.8

The aim of this study was to investigate to what extent polyamine metabolism in the small intestine of the rat is controlled by the enteric nervous system. Polyamine metabolism was followed by measuring the activity of ornithine decarboxylase (ODC) and in some instances also the content of polyamines (putrescine, spermidine and spermine). ODC activity in the intestine was increased when intralumin

This is a commentary on the European Court of Human Rights’ judgment in the CASE OF DELFI AS v. ESTONIA. This text represents the English first version that was translated and published in the Latvian weekly legal journal Jurista vards, in a special issue on the Delfi case.

The cerebrospinal fluid (CSF) biochemical markers (biomarkers) Amyloidβ 42 (Aβ42), total Tau (T-tau) and Tau phosphorylated at threonine 181 (P-tau181) have proven diagnostic accuracy for mild cognitive impairment and dementia due to Alzheimer’s Disease (AD). In an effort to improve the accuracy of an AD diagnosis, it is important to be able to distinguish between AD and other types of dementia (n

OBJECTIVE: Latent autoimmune diabetes in adults (LADA) shares clinical features with both type 1 and type 2 diabetes; however, there is ongoing debate regarding the precise definition of LADA. Understanding its genetic basis is one potential strategy to gain insight into appropriate classification of this diabetes subtype.RESEARCH DESIGN AND METHODS: We performed the first genome-wide association

In the guinea pig basilar artery, acetylcholine and the calcium ionophore A23187 induced endothelium-dependent relaxations, which were not significantly affected by the nitric oxide (NO) synthase inhibitor N(ω)- nitro-L-arginine (L-NOARG; 0.3 mM) or the guanylate cyclase inhibitor ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline-1-one; 1-10 μM), or by these inhibitors combined. However, acetylcholine (

High and low pollen deposition years in the period 1998-2010 were recorded for ten forest-forming trees in Roztocze (SE Poland) using Tauber-style traps. The coincidence of very high/low pollen deposition years recorded in Tauber traps and aerobiological data obtained by volumetric samplers shows that these phenomena occur simultaneously in different places across vast areas of a tree's distributi

Applying in situ surface X-ray diffraction (SXRD) together with on-line mass spectrometry during the CO oxidation over Ru(0001) allows a direct comparison of the reactivity of the non-oxidic state with that of the RuO2(110) covered surface. This comparison reveals that the RuO2(110) surface is a catalytically active phase at least as active as the non-oxidic phase. At high CO and O-2 pressures of

A study is presented about the effects of three glazing colour types (blue, neutral, bronze) on daylight quality, arousal and switch-on patterns for electric lights. This study was carried out using a scale model (1:4) of an office room, where subjective evaluations of the luminous conditions were performed by 36 participants (mean age 23.8 years) with their upper bodies immersed in the model. The

It has been proposed that vascular progenitor cells play an important role in vascular repair, but their possible clinical importance in cardiovascular disease has not been fully characterized. Vascular endothelial growth factor A, placental growth factor and stem cell factor (SCF) are three growth factors that are important in recruiting vascular progenitor cells. In this study, we investigated t

Background and Purpose: Coagulation factor XI (FXI) has an important role in the propagation and stabilization of a thrombus upon vessel injury. High FXI levels have been implicated in thrombotic diseases including ischemic stroke. The aim of our study was to investigate whether FXI gene (F11) variants are associated with ischemic stroke. Methods: The discovery sample, the Sahlgrenska Academy Stud

Chinese hamster ovary (CHO) cells in the plateau phase were seeded in the absence or presence of 5 mM 2-difluoromethylornithine (F(2)MeOrn), an enzyme-activated irreversible inhibitor of ornithine decarboxylase. The thymidine analogue bromodeoxyuridine (BrdUrd, 5 mu M) was added to the culture medium 30 min before sampling of the cells, which occurred 1-17 h after seeding. Using flow cytometry, co

Bjälesjö, Jonas 2013. Rock’n’roll i Hultsfred – Ungdomar, festival och lokal gemenskap (Rock’n’roll in Hultsfred – Youth, Festival and Local Community). Swedish text with a summary in English. Doctoral Dissertation, Lund University, 2013. Published by: Hammarlin bokförlag 2013, Yderhult, Båstad, 0431-755 88, www.hammarlin.se/bokforlag, 200 pages, ISBN: 978-91-979381-0-5. Abstract This study is c