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This paper examines how social media can support communities of patients with chronic illness and their care givers. This study is a qualitative case study and is informed by grounded theory. Sociomateriality is adopted as a theoretical lens to understand and explain the key findings. Our findings suggest that there is a dynamic relation between the contrary roles that social media in chronic care
The Value of Information from Bayesian decision theory can be used to drive decisions within the development of new technologies aiding research screening, technology characteristics, and employment optimization. The selection of a specific application of technology leads to the definition of the decision scenario within the Value of Information framework. Technological performance characteristics
BackgroundEarly detection of cerebral palsy (CP) is essential to initiate timely intervention andimprove long-term outcomes for infants at risk. The General MovementsAssessment (GMA) is a well-established tool for early identification of CP, yet itsimplementation in routine clinical practice faces challenges related to access andscalability.AimThis thesis explores the use of GMA as a screening too
Aims: Social science literature suggests that unlimited trust in others may lead to adverse outcomes, and that moderate trust may be more optimal in social interactions. The aim was to analyze associations between generalized trust in other people and all-cause mortality using a four-alternative generalized trust item that includes moderate trust. Study design: Prospective cohort study. Methods: T
We have used approximately 40 fs pulses from a Ti:sapphire laser to investigate the ultrafast energy transfer and relaxation dynamics in the light-harvesting pigment-proteins of photosynthetic purple bacteria. Our results reveal two new features, not earlier observed in light-harvesting pigments: (1) ultrafast relaxation characterized by a time constant of approximately 20 fs, which we interpret a
Background: Patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HCT) often face complex and evolving needs throughout recovery. Person-centred nursing (PCN) is essential in this context yet remains underexplored in specialised care settings. In Sweden, the Assessment of Rehabilitation Needs Checklist (ARNC) is commonly used in cancer care, but its role in supporting perso
The sintering of pre-pressed powders of iron, copper and nickel has been studied in situ using an Environmental scanning electron microscope. The small samples were slowly heated to sintering temperatures in a reducing atmosphere. Continuous monitoring of the fracture surface of the sample revealed the initial formation of inter-particle bonds at relatively low temperatures for fine particles. The
We hypothesized that positive airway pressure treatment would induce nasal obstruction and decrease nasal cavity due to mucosal swelling. We further hypothesized that subjective and objective nasal obstruction at baseline would negatively affect positive airway pressure adherence. A total of 728 patients with sleep apnea were investigated in the Icelandic Sleep Apnea Cohort at baseline and 2 years
Epithelial ovarian carcinoma has in general a poor prognosis since the vast majority of tumors are genomically unstable and clinically highly aggressive. This results in rapid progression of malignancy potential while still asymptomatic and thus in late diagnosis. It is therefore of critical importance to develop methods to diagnose epithelial ovarian carcinoma at its earliest developmental stage,
Synergistic interplay between Mycobacterium tuberculosis (Mtb) and HIV in coinfected ind-ividuals leads to the acceleration of both tuberculosis and HIVdisease. Mtb, as well as HIV, may modulate the function of many immune cells, including DCs. To dissect the bystander impact of Mfs infected with Mtb on DC functionality, we here investigated changes in DC phenotype, cytokine profiles, and HIV-1 tr
Collagen-induced arthritis (CIA) is one of the most commonly used animal models for Rheumatoid arthritis (RA). CIA is induced in susceptible mouse strains after immunization with heterologous type II collagen (CII). In mice of the H-2q haplotype rat CII (rCII) is used whereas in mice of the H-2r haplotype bovine CII is utilized. The broad objective of this thesis was to gain an understanding of th
We propose an optical method for non-invasive characterisation of wood samples based on two optical techniques: time-resolved diffuse optical spectroscopy and gas in scattering media absorption spectroscopy. While the latter is sensitive to gases present inside wood pores, the former extracts information on the bulk material regarding light scattering and absorption. Measurements on spruce samples
HIV-2 has a lower pathogenicity and transmission rate than HIV-1. Neutralizing antibodies could be contributing to these observations. Here we explored side by side potency and breadth of intratype and intertype neutralizing activity (NAc) in plasma of 20 HIV-1, 20 HIV-2 and 11 dually HIV-1/2 (HIV-D) seropositive individuals from Guinea-Bissau, West Africa. Panels of primary isolates, five HIV-1 a
Previous research has suggested that there is a relationship between the three key components of Donabedian's conceptual model for quality assessments: structure of care, process, and outcome of care. That is, structure predicted both process and outcome of care, and better processes predict better functional outcomes and user satisfaction. The results in this study involving samples of Danish and
Anti-idiotypic antibodies (anti-Id) to autoantibodies are present in several autoimmune diseases and are hypothesized to have regulatory function. Recently we reported the presence of anti-Id to a major type 1 diabetes-associated autoantibody (CAD65Ab) in sera of healthy individuals. Our current assay for the detection of GAD65Ab-specific anti-Id requires the initial removal of anti-Id from the se
This thesis provides knowledge of occupational engagement in day centres for people with psychiatric disabilities and contributes to measurement development in the area of occupational engagement. The first study focused on the characteristics of the occupations carried out at the day centre by exploring occupational engagement using time-use diaries with a person-environment-occupation perspectiv
