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A tightly focused radially polarized laser beam forms an unusual bimodal held distribution in an optical lambda/2-microresonator. We use a single-molecule dipole to probe the vector properties of this field distribution by tuning the resonator length with nanometer precision. Comparing calculated and experimental excitation patterns provides the three-dimensional orientation of the single-molecule
Hobbing is a common manufacturing method when producing helical, involute gears. In order to increase tool life and surface finish, an accurate method to determine chip geometry is needed. Although this accurateness may involve numeric solutions, the geometric description must, as far as possible, be analytic and give a description of the continuously changing chip geometry. In this report, the c
One of the big obstacles for understanding the nervous system is its inherent complexity. It poses problems when interpreting both experimental and theoretical studies since we are currently forced to consider only reduced variants of the actual circuitry of the brain. Since there exist problems that do not appear until a system is sufficiently complex, there are no guarantees that the results ste
Popular Abstract in Swedish En ordentlig bildning av det centrala nervsystemet är viktigt för ett nyfött barn eller en vuxen. Den senaste tidens kartläggning av människans arvsmassa har lett till identifiering av ungefär 23000 gener, många av dem aktiva i det utvecklande nervsystemet. Men lite är känt om deras funktion och hur de samverkar för att påverka utvecklingen av organ så komplexa som den Morphogens such as Hedghog, Wnt, FGF, and retinoic acid are important signals whose concentrations need to be tightly regulated in the vertebrate embryo to ensure body axis development and formation of the central nervous system. We first show that the intracellular cytoplasmic protein XSufu acts as a dual regulator of Hedgehog (Hh) and Wnt signals during neural induction and patterning in the Xen
Many species of Dytiscus diving beetles exhibit intrasexual dimorphism, e. g., the elytra is smooth in some females and grooved in others. However, the expression of the grooves and whether they are a product of heredity or the environment remain unknown. One Japanese species, Dytiscus sharpi sharpi Wehncke, 1875, also shows female dimorphism, with grooved and smooth morphs, while D. sharpi validu
We establish equality between the essential spectrum of the Schrödinger operator with magnetic field in the exterior of a compact arbitrary dimensional domain and that of the operator defined in all the space, and discuss applications of this equality.
Pollution-induced community tolerance (PICT) of soil bacteria to the antibiotic tylosin was studied over 95 days. Tylosin was added at increasing concentrations, together with different amounts of alfalfa to study the effects of substrate addition on PICT and bacterial growth in soil. The leucine incorporation technique was used to estimate bacterial growth and as a detection method in the PICT co
Popular Abstract in Swedish Till och med kroppens allra enklaste celler är så avancerade att vi inte förstår i detalj hur de fungerar eller hur de påverkar kroppen. Nervceller tillhör kroppens mer avancerade celler och vi får erkänna att all den kunskap vi har om dem är mindre än vad som finns att veta. Komplexiteten hos hjärnan är mångfalt större för nervcellerna kommunicerar blixtsnabbt med varaIn the hippocampus, dendritic spines are compartmentalized postsynaptic micro-domains in the excitatory synapse. Subsets of bigger and mushroom-shaped hippocampal dendritic spines contain tubules and cisterns of endoplasmic reticulum (ER) that are connected to the soma and dendrites of the neuron. These ER containing spines differ in their ability to retain ER. We hypothesized a functional couplin
A new method for detecting jerks in safety critical events, based on the characteristics of the braking caused by the driver in time critical situations, has been developed and evaluated in a small pilot test and also applied on a naturalistic driving study. A portable event data recorder, capable of measuring and recording acceleration profiles for a predetermined time period before and after the
Background. Uraemia increases oxidative stress, plasma titres of antibodies recognizing oxidized low-density lipoprotein (oxLDL) and development of atherosclerosis. Immunization with oxLDL prevents classical, non-uraemic atherosclerosis. We have investigated whether immunization with oxLDL might also prevent uraemia-induced atherosclerosis in apolipoprotein E knockout (apoE-/-) mice. Methods. ApoE
Populärvetenskaplig sammanfattning. Katalyskammare för aktivitetsmätning med laser. Katalysatorer är oumbärliga i såväl livsprocesser som industriella tillämpningar. Bilismen är ett exempel där katalysatorer används vid såväl bränsletillverkning som avgasrening. Med hänsyn till miljön måste mycket ständigt förbättras, också katalytiska processer. I mitt examensarbete har jag karakteriserat en ny Industrial catalysts are very complex systems, often produced of nanoparticles dispersed in a so-called support material to maximize the surface area and minimize the cost. These catalysts are very difficult to study in surface science. Therefore industrial catalysts have been developed in a trial-and-error approach, with the loss of the fundamental understanding of the reactions. In surface scien
Understanding Sense Perception We all need to perceive sensations such as pain; cold or pungent chemicals in order survive. In elucidating sense perception, we investigate TRPA1 which is a major player in sensation. Transient Receptor Potential (TRP) is a large family of ion channels that are found in membrane of biological cells. They were first discovered in fruit fly in 1969 and this discovery
In this Master's thesis I present a means of finding active sources of cortical electrical activity from electroencephalogram (EEG) data acquired during operation of a brain-computer interface (BCI). A novel subspace-based technique was used to suppress spatially correlated EEG interference sources, followed by a technique that estimates the source parameters with a near maximum likelihood per
