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Objective: Familial risks of glomerulonephritis (acute, chronic and unspecified glomerulonephritis) have not been studied. This study aims to determine the familial risks of glomerulonephritis. Methods: Individuals born from1932 onwards diagnosed with glomerulonephritis (acute [n = 7011], chronic [n = 10,242] and unspecified glomerulonephritis [n = 5762]) were included. The familial risk (Standard

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We consider a real-time system of multiple tasks, each task having a plant to control. The overall quadratic control cost is to be optimized. We exploit the periodicity of the task response time, which corresponds to a periodic delay pattern in the feedback control loop. Perturbed periods are used as a tool to find a finite hyperperiod. We present an analytical procedure to design a periodic linea

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We study the exciton dynamics in an optically excited nanocrystal quantum dot. Multiple exciton formation is more efficient in nanocrystal quantum dots compared to bulk semiconductors due to enhanced Coulomb interactions and the absence of conservation of momentum. The formation of multiple excitons is dependent on different excitation parameters and the dissipation. We study this process within a

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Laser-induced fluorescence imaging of the NH radical using excitation in the (0-0) and (1-0) vibrational bands of the A3Π-X3Σ– electronic transition is characterized in premixed NH3-air flames. Filtered detection for excitation of the (1-0) band is found to be beneficial for measurement conditions with a challenging background and/or interferences. Concentration evaluation for excitation in the (0

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The Nordic countries represent an institutional setting with tax-based health care financing and universal access to health care services. Very few health care services are excluded from what are offered within the publically financed health care system. User fees are often non-existing or low and capped. Nevertheless, the markets for voluntary private health insurance (VPHI) have been rapidly exp

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Laser-induced fluorescence measurements have been performed in turbulent non-premixed flames close to the lift-off point and in laminar premixed acetylene flames. The spectrally analyzed fluorescence signal showed good correspondence to known spectra from glyoxal (C2H2O2). Laser-induced fluorescence spectra from glyoxal vapor using the same excitation wavelength of 428 nm showed the same strongest

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This paper focuses on the regulation of RNA production for in vitro synthetic gene networks. We consider the problem of matching the production rate of several RNA species concurrently transcribed to form RNA complexes. We design regulatory feedback loops based on two schemes: negative auto-regulation (which can minimize the potentially harmful amount of molecules not used to form products) and cr

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Large-scale food storage has been identified at an Early Mesolithic settlement on the east coast of Sweden, implying a delayed-return subsistence strategy. The excavation and analysis of the contents of a 9200-year-old construction, combined with ethnographic analogies and modern knowledge of microbial activity, suggest that fish was fermented at the site. The identification of a foraging economy

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Background Although there is evidence of an association between antibiotic consumption and resistant bacteria on a population level, the relationship on an individual level has been less well studied, particularly in terms of nasopharyngeal colonization. We have therefore analysed this association, using data from a closely followed cohort of children taking part in a vaccination trial. Methods 10

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The transcription factor Sox4 has been proposed to underlie the increased type 2 diabetes risk linked to an intronic single nucleotide polymorphism in CDKAL1. In a mouse model expressing a mutant form of Sox4, glucose-induced insulin secretion is reduced by 40% despite normal intracellular Ca2+ signaling and depolarization-evoked exocytosis. This paradox is explained by a fourfold increase in kiss

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In this work, we utilize classical polymer density functional theory (DFT) to study gelation in systems containing colloidal particles onto which polymers are grafted. The solution conditions are such that the corresponding bulk system displays a lower critical solution temperature (LCST). We specifically compare our predictions with experimental results by Shay et al. (J. Rheol. 2001, 45, 913-927

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We have previously shown that the reciprocal translocation t(6;7) associated with the spontaneous immunocytoma of the Louvain rat (RIC) leads to the juxtaposition of myc to the IgH cluster. In 10 of 14 tumors investigated the breakpoints on the myc carrying chromosome were clustered in a 1.5 kb region 5' of the intact gene, proximal to the myc promoters. In this paper we describe the effect of the

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BACKGROUND: Designing amino acid sequences that are stable in a given target structure amounts to maximizing a conditional probability. A straightforward approach to accomplishing this is a nested Monte Carlo where the conformation space is explored over and over again for different fixed sequences; this requires excessive computational demand. Several approximate attempts to remedy this situation

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We calculate differential cross sections for exclusive double diffractive (EDD) production of open charm in proton-proton and proton-antiproton collisions. Sizeable cross sections are found. The EDD contribution constitutes about 1% of the total inclusive cross section for open charm production. A few differential distributions are shown and discussed. The EDD contribution falls faster both with t

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Near-threshold production of boson pairs is considered within the framework of the model of unstable particles with smeared mass. We describe the principal aspects of the model and consider the strategy of calculations including the radiative corrections. The results of calculations are in good agreement with LEP II data and Monte-Carlo simulations. Suggested approach significantly simplifies calc

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The split SUSY scenario with light Higgsino states is treated as an application to the dark matter problem. We have considered the structure of the neutralinonucleon interaction and calculated cross-section of the neutralinonucleon scattering. The decay properties of the lightest chargino and next lightest neutralino are analyzed in details.

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Anomalous dimensions of high-twist Wilson operators in generic gauge theories occupy a band of width growing logarithmically with their conformal spin. We perform a systematic study of its fine structure in the autonomous SL (2) subsector of the dilatation operator of planar N = 4 super-Yang-Mills theory which is believed to be integrable to all orders in 't Hooft coupling. We resort in our study

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The experimental core-level spectra for the noble metals Cu, Ag, and Au are shown to contain intrinsic satellite features. In the case of Ag, however, the identification is somewhat less certain than for the other two metals. The satellites are interpreted as being due to d-valence-electron shakeup processes. This view is supported by calculations of the multiplet splittings and also by calculatio