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OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systoli
The LPJ-GUESS dynamic vegetation model uniquely combines an individual-and patch-based representation of vegetation dynamics with ecosystem biogeochemical cycling from regional to global scales. We present an updated version that includes plant and soil N dynamics, analysing the implications of accounting for C-N interactions on predictions and performance of the model. Stand structural dynamics a
This thesis examines the creative appropriation of Shakespeare in theory and practice. It is based on close readings of King Lear alongside three appropriations of the play in works of fiction by three North American women writers: Jane Smiley, Anne Tyler, and Margaret Atwood. The aim is to demonstrate how a ‘palimpsestic’ reading, i.e. a reading in which the reader oscillates between ‘pre-text’ a
The purpose of this study was to describe nurses' experiences of interactions with family members in intensive care units. Ten experienced Registered Nurses were interviewed, and the interview text was qualitatively analysed by its content. Nursing of families was experienced as an essential, necessary and demanding task, and no systematic assessment and intervention with families were talked abou
Popular Abstract in Swedish Blodgruppering med genteknik - studier av ABO-systemets arvsanlag Populärvetenskaplig sammanfattning på svenska Blodtransfusioner som utfördes före sekelskiftet slutade ofta med svåra komplikationer och i många fall patientens död. Scenariot förändrades dramatiskt till det bättre i och med den österrikiske läkaren Karl Landsteiners upptäckt av blodgruppssystemet ABO (The ABO blood group system is undoubtedly the most important genetic and phenotypic marker in clinical transfusion medicine. The A and B determinants are immunodominant, terminally located carbohydrate residues of glycoconjugates on erythrocytes and other cell surfaces. The enzymes responsible for assembly of these structures are glycosyltransferases encoded by the ABO genes on chromosome nine. T
Popular Abstract in Swedish Diabetes är en världssjukdom – om 50 år räknar det internationella diabetesförbundet med att en tiondel av världens befolkning har någon form av diabetes. Diabetes innebär att kroppen inte kan ta hand om allt socker som man äter. Detta medför att sockerhalten i blodet blir för högt. Högt blodsocker gör att kroppens celler arbetar konstant, och om blodsockret är för högtThe primary aim of this thesis was to investigate the role of G protein coupled receptors (GPCRs) in insulin secretion and beta-cell survival. The second aim was to determine which pathway is involved in insulin release and beta-cell protection via GPCRs. This has been investigated in three different studies, which concluded the following: Study 1) GPR30 is expressed in female mice pancreatic isle
The phenomenon of intermedial conceptual loans is central to our understanding of the time-based arts. This thesis focuses on the usage of the term storytelling with regard to jazz improvisation. The aim of the investigation is to clarify how this concept is used by Swedish jazz practitioners. The framework of the study includes theories of narrativity and of metaphor as well as educational and
In this paper we develop an Enterprise Systems Implementation Methodology in Action framework. The framework is grounded in contemporary views on methodology in action (theoretical grounding) and enhanced by an empirical study (empirical grounding). The notion of Implementation Methodology in Action, as articulated in this paper, integrates two complementary views that conceptualise a methodology
Resistivity measurements were carried out in order to identify preferential seepage paths in a small dam in central Sweden. Increased seepage flow had been observed at high reservoir levels. Repeated resistivity measurements were performed along the dam crest during 24 hours controlled rising of the reservoir. Each measurement data set was compared to the original reference data set using time-lap
Our group previously demonstrated that carbon dioxide (CO2) levels in heavily occupied schools correlate with the levels of airborne bacterial markers. Since CO2 is derived from the room occupants, it was hypothesized that in schools, bacterial markers may be primarily increased in indoor air because of the presence of children: directly from skin microflora or indirectly, by stirring up dust from
The biological response of increased manganese in seawater was tested experimentally with the oyster species Crassostrea gigas by adding, once per day, a fixed quantity of MnCl2 to the container where the oysters were living. Uptake of Mn2+ in the shell was traced with cathodoluminescence and quantified with a high spatial resolution proton microprobe. The daily addition of MnCl2 resulted in the v
OBJECTIVE: Experimental studies in mice have attributed T-helper (Th) 1 and Th2 cells important roles in atherosclerosis, but the clinical importance of these cells in cardiovascular disease (CVD) remains to be clarified. Here, we investigated associations between Th1 and Th2 cells, carotid intima-media thickness, and cardiovascular risk. METHODS AND RESULTS: Blood drawn at baseline and incident c
