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OBJECTIVE: Genome-wide association studies have begun to elucidate the genetic architecture of type 2 diabetes. We examined whether single nucleotide polymorphisms (SNPs) identified through targeted complementary approaches affect diabetes incidence in the at-risk population of the Diabetes Prevention Program (DPP) and whether they influence a response to preventive interventions. RESEARCH DESIGN
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At the first Nordic meeting for linguists with a research interest in reading and writing, held in Løgumkloster, Denmark, in 1987, we reported on a longitudinal study we had just started. The aim of the study was to find out which kind of linguistic disabilities are the most damaging for the development of reading and writing (Magnusson & Nauclér 1990 a, b). When reading is looked upon as a li
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The aim of the study was to explore Swedish classrooms and to identify creativity related moments occurring in ordinary classes and discuss these with teachers and students. The moments were individual actions, interactions between classroom participants or creative ideas/products arising in the classroom (by teacher or student) that were deemed to be either associated with creativity in a positiv
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Purpose of this paper: This paper proposes a framework for identifying potential risk and gain sharing challenges related to implementing collaborative change initiatives in supply chains, and uses the framework to explore risk and gain sharing in implementing radio frequency identification (RFID) technology.
Design/methodology/approach: The empirical investigation, based on case study researc
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Abstract in German Die Lektüre von Still Songs eröffnet einen neuen, interessanten und zugleich kritischen Blick auf Celans „MusikGedichte“ und deren Vertonungen und auf die Celan-Forschung überhaupt. Passagen zur Detailebene einzelner Gedichte – wie Todesfuge, Schlaflied, Saitenspiel, Engführung oder Fadensonnen – und deren Vertonungen – durch Tilo Medek, Erhard Karkoschka, Harrison Birtwistle, A
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The metabolite produced by one enzyme in a metabolic pathway can be transferred to the next enzyme in the pathway by free diffusion via solution or by channelling in an enzyme-enzyme complex without prior release of the metabolite to solution. While metabolite channelling is known to occur in systems where stable multienzyme complexes form, conflicting views have been expressed as to its existence