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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To evaluate the benefits and harms of stem cell-based interventions for the treatment of stroke in newborn infants compared to control (placebo or no treatment) or stem-cell based interventions of a different type or source.
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This presentation discusses ways in which veganism can be conceptualized as political participation. What are the political aspects of the increasingly popular practice, which by some is understood as a personal dietary choice, by others a conscious lifestyle, and by still others a part of a broader emancipatory project of multispecies justice? The presentation argues that the rising vegan movemen
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Biomass is an environmentally friendly renewable energy source and carbon-neutral fuel alternative. Direct combustion/gasification of biomass in the dense particle-fluid system is an important pathway to biomass energy utilization. To efficiently utilize biomass for energy conversion, a full understanding of biomass thermal conversion in lab/industrial-scale equipment is essential. This thesis aim
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Mesenchymal stem/stromal cells (MSCs) are found in almost all postnatal organs. Under appropriate environmental cues, multipotency enables MSCs to serve as progenitors for several lineage-specific, differentiated cell types. In vitro expansion and differentiation of MSCs give the opportunity to obtain hardly available somatic cells, such as neurons. The neurogenic potential of MSCs makes them a pr
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Turbulent emulsification is an important unit operation in chemical engineering. Due to its high energy cost, there is substantial interest in increasing the fundamental understanding of drop breakup in these devices, e.g., for optimization. In this study, numerical breakup experiments are used to study turbulent fragmentation of viscous drops, under conditions similar to emulsification devices su
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INTRODUCTION: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological background of non-small cell lung cancer (NSCLC).METHODS: We established a multiplexed fluorescence imaging pipeline to spatially quantify 13 immune cell subsets in 359 NSCLC
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The common Deep Eutectic Solvent (DES) ‘ethaline’ (1:2 choline chloride:ethylene glycol) was examined here as a basis for the self-assembly of the surfactant dodecyltrimethylammonium bromide (C12TAB). A phase diagram was constructed, showing evidence for a L1 (micellar) phase, confirmed by tensiometry to have a room temperature critical micelle concentration (CMC) of 1.2 wt.%. Small angle neutron
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Chromothripsis is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in cancer and other diseases. Recent studies in selected cancer types have suggested that chromothripsis may be more common than initially inferred from low-resolution copy-number data. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Can
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In recent years, the combination of the digitization of the field of pathology and increased computational power has led to a big increase in research of computer-aided diagnostics using systems based on artificial intelligence (AI). This includes detection and classification of prostate cancer, where several studies have shown great promise in automated prostate cancer grading using deep learning
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This book discusses the importance of developing routininized behaviours in new venture development, specifically highlighting the unique challenges that academic spin-offs face in this vital step towards successful business creation. During the early development stage, new ventures are informally established and have few routines that inform organizational performance. However, the process of new
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Combining hard and soft costal protection solutions can be an appropriate measure to enhance structure lifetime. This study aims to quantify the morphological evolution of the nourished stretch and adjacent coastlines. A small-scale beach nourishment has been performed in front of a rock revetment at site in Faxe Ladeplads in Zealand, Denmark. The overall objective is to learn more about the dynam
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Micron-thick hydrogel films with ordered 3D mesostructures form spontaneously at the interface of polyelectrolyte-surfactant solutions. Here we demonstrate that by rationally designing the micelle shapes it is possible to predict and so tailor the nanostructure formed within surfactant-polyelectrolyte films. Using quaternary ammonium surfactants with a range of packing parameters, we demonstrate t
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The recently constructed H4-VLE beam line, a tertiary extension branch of the existing H4 beam line in the CERN North Area, was commissioned in October 2018. The beam line was designed with the purpose of providing very low energy (VLE) hadrons and positrons to the NP-04 experiment, in the momentum range of 1-7 GeV/c. The production of these low-energy particles is achieved with a mixed hadron (pi
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Hybrid zone movement may result in substantial unidirectional introgression of selectively neutral material from the local to the advancing species, leaving a genetic footprint. This genetic footprint is represented by a trail of asymmetric tails and displaced cline centres in the wake of the moving hybrid zone. A peak of admixture linkage disequilibrium is predicted to exist ahead of the centre o
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We developed a panel of 44 nuclear genetic markers and applied this to two hybridizing species of marbled newts in the north (Triturus marmoratus) and the south (Triturus pygmaeus) of the Iberian Peninsula, to investigate pattern and process of interspecific gene flow. The northernmost occurrence of T. pygmaeus genetic material was in a T. marmoratus population north of the Vouga river estuary. Th
