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This paper analyzes the influence of the interannual variability of climatic drought on ecological and hydrological droughts for a basin in the central Spanish Pyrenees using variables derived from observations and hydro-ecological simulation in order to determine the possible connection between meteorological, ecological and hydrological drought considering a cascading approach and encompassing d
BACKGROUND: A recently published East Asian genome-wide association study of Parkinson;s disease (PD) reported 2 novel risk loci, SV2C and WBSCR17.OBJECTIVES: The objective of this study were to determine whether recently reported novel SV2C and WBSCR17 loci contribute to the risk of developing PD in European and East Asian ancestry populations.METHODS: We report an association analysis of recentl
Despite coalition governments being the most widespread form of government, many aspects of coalition politics are still poorly understood. This is especially true for questions relating to the role of the prime minister party within the coalition. Being the prime minister party seems to imply considerable influence, but little evidence actually exists as to the factors shaping the influence of th
In Sweden students’ encounters with English in and out of school are very different. Spending around 20 hours per week in English-mediated environments outside of school, they are often engaged in richly meaningful activities. Consequently, many young people believe they learn as much of their English as a result of participation in English-mediated leisure time activities as they do from textbook
The evolution of digital manufacturing is inherently linked with Computer Integrated Manufacturing (CIM) since 1980. CIM triggers the partial or fully automation in the industrial sector. Due to the global competitiveness and mandatory requirement of triple bottom line sustainability approach, the industries are on the verge of adapting digitalized sustainable manufacturing. The Digital manufactur
Sex chromosomes have evolved repeatedly across the tree of life and often exhibit extreme size dimorphism due to genetic degeneration of the sex-limited chromosome (e.g. the W chromosome of some birds and Y chromosome of mammals). However, in some lineages, ancient sex-limited chromosomes have escaped degeneration. Here, we study the evolutionary maintenance of sex chromosomes in the ostrich (Stru
Background: The World Health Organization has adopted a resolution on sepsis and urged member states to develop national processes to improve sepsis care. In Sweden, sepsis was selected as one of the ten first diagnoses to be addressed, when the Swedish government in 2019 allocated funds for patient-centred clinical pathways in healthcare. A national multidisciplinary working group, including a pa
Regular exercise leads to widespread salutary effects, and there is increasing recognition that exercise-stimulated circulating proteins can impart health benefits. Despite this, limited data exist regarding the plasma proteomic changes that occur in response to regular exercise. Here, we perform large-scale plasma proteomic profiling in 654 healthy human study participants before and after a supe
Norm enforcement may be important for resolving conflicts and promoting cooperation. However, little is known about how preferred responses to norm violations vary across cultures and across domains. In a preregistered study of 57 countries (using convenience samples of 22,863 students and non-students), we measured perceptions of the appropriateness of various responses to a violation of a cooper
Objective: To validate Vergouwe's prediction model using the Swedish and Norwegian Testicular Cancer Group (SWENOTECA) RETROP database and to define its clinical utility. Materials and methods: Vergouwe's prediction model for benign histopathology in post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) uses the following variables: presence of teratoma in orchiectomy specimen; pre-ch
Collagen is the main organic building block of musculoskeletal tissues. Despite collagen being their smallest load bearing unit, these tissues differ significantly in mechanical function and properties. A major factor behind these differences is their hierarchical organization, from the collagen molecule up to the organ scale. It is thus of high importance to understand the characteristics of each
Focused environmental research projects and continuously operating research infrastructures (RIs) designed for monitoring all subdomains of the Earth system contribute to global observing systems and serve as crucial information sources for environmental scientists in their quest for understanding and interpreting the complex Earth System and contribute to global observing systems. The EU funded E
Haemophilus influenzae is a major cause of community-acquired pneumonia. While studied extensively in various laboratory models, less is known about the cell function while inside the human lung. We present the first analysis of the global gene expression of H. influenzae while the bacteria are in the lung during pneumonia ( in vivo conditions) and contrast it with bacterial isolates that have
The deposited dose of particles in the respiratory tract is an important factor for understanding health effects of aerosol particles. It is a combination of the exposure, volume of inhaled air and particle deposition. At increasing activity the minute ventilation ( volume of breath x number of breaths ) increase . Little is known about if and how this affects the regional particle deposition.
A structural design process may include various load cases for which a sufficient load-bearing capacity must be demonstrated. In addition to static load cases, a verification of dynamic loads, e.g. accidental loads such as blast and impact loading, may be required. To this end, the response may be estimated using a computational model representing an idealized structure. Particularly in the concep
The polarization switching dynamics for Hf 1-x Zr x O 2 (HZO) integrated on InAs is studied as a function of pulse width and amplitude. Due to a mixed ferroelectric/antiferroelectric phase at x=0.8, a more gradual total polarization update is shown compared to a fully ferroelectric Hf 0.5 Zr 0.5 O 2 stack. A lowered operating voltage is achieved in Hf 0.2 Zr 0.8 O 2 by activating an inner ferroele
Negated forms have been shown to cause a higher processing cost for language comprehension in the form of higher error rates and longer processing times. Studies that tested prefixal negation (e.g. unhappy) found conflicting results as to whether these forms are processed as negated forms or as single lexical items without any processing cost (Hoosain, 1973; Sherman, 1976, 1973). The present study
