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Rhinovirus infection is a main trigger of asthma and COPD exacerbations. dsRNA, a viral replication intermediate, is sensed by pattern recognition receptors in the airway epithelium leading to down-stream induction of anti-viral interferons. Several studies have demonstrated that the rhinoviral-induced interferon response can be deficient in asthmatics, possibly resulting in more severe and length
BackgroundIn emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety and effectiveness of the ESC 0h/1h
The neutron-unbound isotope Be13 has been studied in several experiments using different reactions, different projectile energies, and different experimental setups. There is, however, no real consensus in the interpretation of the data, in particular concerning the structure of the low-lying excited states. Gathering new experimental information, which may reveal the Be13 structure, is a challeng
Objectives: To identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates to identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates in Sweden. Methods: The study was a retrospective, observational nationwide laboratory-based surveillance for fungaemia and fungal meningitis and was conducted from September 2
This chapter discusses the Directive on Administrative Cooperation and the Recovery Directive.
In spite of earlier implantation, bilateral implants and advances in the care of deaf children with cochlear implants (CI) within-group variation in language skills is large. We use three tasks with predictive value of language impairment in Swedish to identify children with CI most at risk for persistent difficulties in language development, in need of language intervention. The clinical markers
Objective To measure CSF levels of biomarkers reflecting microglia and astrocytes activation, neuroinflammation, and cerebrovascular changes and study their associations with the core biomarkers of Alzheimer disease (AD) pathology (β-amyloid [Aβ] and tau), structural imaging correlates, and clinical disease progression over time. Methods The study included cognitively unimpaired elderly (n = 508),
Försvarsadvokaters arbete utspelar sig i emotionellt laddade men emotionellt begränsade situationer. Detta är särskilt påtagligt i brottmålsrättegångar. Upprivna klienter, oförutsebara avbrott, skakande bevis, emotionella målsägande, till och med moralisk misstänksamhet förväntas hanteras på ett korrekt och passande sätt. Den här avhandlingen analyserar hur detta görs i en svensk kontext, med specDefence lawyers’ work takes place in emotionally charged, yet emotionally constraining situations. This is particularly evident in criminal trials. Distressed clients, unforeseeable disruptions, disturbing evidence, emotional plaintiffs and even moral suspicions should all be managed in a proper and appropriate manner. Loyalty Work analyses how this is done in the context of Sweden, with specific
BACKGROUND: Tortillas were prepared from two (blue and regular white) maize varieties and compared with regard to chemical composition and in vitro starch digestibility, i.e., available starch (AS), total (RS) and retrograde (RRS) resistant starch contents, amylolysis rate and predicted glycemic index (pGI). The impact of cold storage (4°C) on digestibility was also investigated. RESULTS: Despite
Nixtamalized maize flours elaborated by four factories in Mexico were used for tortilla preparation. Samples were stored at 4°C for up to 72 h and their in vitro starch digestibility features were evaluated. Moisture content was different between flour and tortilla but no evident relation could be established. Protein and lipid levels were lower in tortillas than in flour but ash content was not d
The OECD countries finance their health care through a mixture of taxes, social insurance contributions, private insurance premiums and out-of-pocket payments. The various payment sources have very different implications for both vertical and horizontal equity and on redistributive effect which is a function of both. This paper presents results on the income redistribution consequences of the heal
The paper presents some quantitative evidence on the relationship between certain socioeconomic and demographic factors and per capita health care expenditure in Africa. First, GNP per capita, percentage of births attended by health staff and foreign aid received per capita together explained 78.3% of the variance in health care expenditure. Second, per capita GNP is the most significant factor ex
The growth of aerosol due to the aqueous phase oxidation of sulfur dioxide by ozone was measured in laboratory-generated clouds created in the Cosmics Leaving OUtdoor Droplets (CLOUD) chamber at the European Organization for Nuclear Research (CERN). Experiments were performed at 10 and-10 °C, on acidic (sulfuric acid) and on partially to fully neutralised (ammonium sulfate) seed aerosol. Clouds we
IMPORTANCE The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core neuropathological feature of Alzheimer disease (AD), but its diagnostic utility is unclear. OBJECTIVE To examine the discriminative accuracy of [18F]flortaucipir for AD vs non-AD neurodegenerative disorders. DESIGN, SETTING, AND PARTICIPANTS In this cross-
We fabricate photodetectors based on solution-processed single CH3NH3PbBr3 microcrystals (MCs) and map the two-photon absorption (TPA) excited photocurrent (PC) with spatial resolution of 1 μm. We find that the charge carrier transport length in the MCs depends on the applied electric field, and increases from 5.7 μm for 0.02 V bias (dominated by carrier diffusion) to 23.2 μm for 2 V bias (dominat
The existence of two genetic variants (allotypes) of normal human factor IX is used for carrier detection in three families with severe and one with mild haemophilia B. By analysis of IX:Ag with two different monoclonal antibodies in 93 members of the families, allelic assignment is shown to be a complement in carrier diagnosis to genotypic DNA studies. Allelic assignment makes possible a reliable
Multi-agent coordination control usually involves a potential function that encodes information of a global control task, while the control input for individual agents is often designed by a gradient-based control law. The property of Hessian matrix associated with a potential function plays an important role in the stability analysis of equilibrium points in gradient-based coordination control s
The elliptic (v2), triangular (v3), and quadrangular (v4) flow coefficients of π±, K±, p+p¯,Λ+Λ¯,KS0, and the ϕ-meson are measured in Pb-Pb collisions at sNN=5.02 TeV. Results obtained with the scalar product method are reported for the rapidity range |y| < 0.5 as a function of transverse momentum, pT, at different collision centrality intervals between 0–70%, including ultra-central (0–1%) collis
Moral panics are events that occur when societies react to a condition, episode, person or group of persons inside their society, which are seen as threats to the society’s core values or beliefs. The concept of moral panic has been successfully employed in the fields of sociology and criminology for well over 40 years. However, it has remained fairly unknown to social psychologists. In this paper
