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Introduction: Individuals with type 2 diabetes (T2D) are at high risk of experiencing atherosclerotic cardiovascular disease (ASCVD), which is associated with morbidity, mortality and healthcare resource utilisation. Clinical guidelines recommend the use of glucose-lowering medications with cardiovascular benefits in individuals with T2D and cardiovascular disease, but there is evidence that this
Context: In the past decades, several ecological engineering (eco-engineering) programs have been conducted in China, leading to a significant increase in regional carbon sink. However, the contribution of different eco-engineering programs to carbon uptake is still not clear, as the location of different programs is difficult to identify, and their impacts are concurrent with climate change. Obje
The ongoing conflict and the impact of Russia–Ukraine war pose significant challenges to various sectors, including the agri-food industry. The agricultural industry serves as a backbone for many world economies, contributing significantly to their gross domestic product. The continuing war and shifting economic environment have greatly affected grain production, encompassing crops like wheat, mai
Anthropogenically land cover modifications and human presence in natural environments are not without consequences to ecological processes. From a conservation perspective, these consequences are worrisome specially when considering the human domination of terrestrial ecosystems worldwide. The recent loss of wilderness areas has been described as catastrophic despite pro-active conservation scheme
To avoid catastrophic consequences of impending ecological crises our socio-economic systems need to be transformed in rapid and radical manners. Focusing on working life and Sweden as an example for countries of the Global North with a social-democratic welfare tradition, we ask how social protection systems may be reorganised according to the concept of ‘sustainable welfare’, the satisfaction of
Background Statistical analyses of clinical data are a cornerstone in understanding pathomechanisms of disorders. In rare disorders, cross-sectional datasets of sufficient size are usually not available. Taking AA amyloidosis as an example of a life-threatening rare disorder resulting from of uncontrolled chronic inflammation, we propose techniques from time series analysis to predict organ respon
Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell
Abstract not available.
Shopping has since long been recognized as a possible source of enjoyment. It has been argued that consumers of today devote ever more of their spare time to shopping. Within the domain of marketing, scholars have been successful in outlining consumers' motives for engaging in shopping as a leisure-time enjoyment. Minor attention has however been devoted to explorations of how or why such shopping
Protein S functions as a cofactor for tissue factor pathway inhibitor (TFPI) and activated protein C (APC). The sex hormone binding globulin (SHBG)-like region of protein S, consisting of two laminin G-like domains (LG1 and LG2), contains the binding site for C4b-binding protein (C4BP) and TFPI. Furthermore, the LG-domains are essential for the TFPI-cofactor function and for expression of full APC
In terrestrial ecosystems, the largest pool of amorphous silica (ASi) is stored in soils and is an important reservoir of biologically active Si for the global biogeochemical cycling of Si. Only limited data are available that quantify the size of this reservoir and often these estimates are made from the physical separation of silt-sized phytoliths, which can underestimate the ASi pool. Soil samp
