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Climate warming raises the question whether high-latitude landscape still function as net carbon (C) sinks. By compiling an integrated C balance for an intensely studied subarctic catchment, we show that this catchment's C balance is not likely to be a strong current sink of C, a commonly held assumption. In fact, it is more plausible (71% probability) that the studied catchment functions as a C s
This study presents GIS-based estimates of permafrost extent in the northern circumpolar region during the Last Glacial Maximum (LGM), based on a review of previously published maps and compilations of field evidence in the form of ice-wedge pseudomorphs and relict sand wedges. We focus on field evidence localities in areas thought to have been located along the past southern border of permafrost.
Background: Activation of the renin-angiotensin-aldosterone-system (RAAS) has been proposed to contribute to development of vascular complications in type 2 diabetes (T2D). The aim of the present study was to determine if plasma renin levels are associated with the severity of vascular changes in subjects with and without T2D. Methods: Renin was analyzed by the Proximity Extension Assay in subject
The savanna ecosystem is one of the most dominant and complex terrestrial biomes, deriving from a distinct vegetative surface comprised of co-dominant tree and grass populations. While these two vegetation types co-exist functionally, demographically they are not static but are dynamically changing in response to environmental forces such as annual fire events and rainfall variability. Modelling s
A realistic simulation of snow cover and its thermal properties are important for accurate modelling of permafrost. We analyse simulated relationships between air and near-surface (20 cm) soil temperatures in the Northern Hemisphere permafrost region during winter, with a particular focus on snow insulation effects in nine land surface models, and compare them with observations from 268 Russian st
A coupled-column liquid chromatographic system using solid phase extraction pre-columns for the seven chlorotriazines, atrazine, desethylatrazine, desisopropylatrazine (DIA), propazine, simazine, desethylterbuthylazine and terbuthylazine, using photodiode-array detection (PDAD) was developed. Restricted access (RA), was investigated as a pre- column material, making use of non-adsorptive size excl
Climate change could pose a major challenge to efforts towards strongly increase food production over the coming decades. However, model simulations of future climate-impacts on crop yields differ substantially in the magnitude and even direction of the projected change. Combining observations of current maximum-attainable yield with climate analogues, we provide a complementary method of assessin
PREMISE OF THE STUDY: The role of floral scent in facilitating reproductive isolation between closely related plants remains poorly understood. Yucca brevifolia and Yucca jaegeriana are pollinated by different moth species in allopatry, but in a narrow contact zone, pollinator–host specificity breaks down, resulting in hybridization between species. We explored the chemical basis for reproductive
Purpose: In Gaucher disease, diminished activity of the lysosomal enzyme, acid β-glucosidase, leads to accumulation of glucosylceramides and related substrates, primarily in the spleen, liver, and bone marrow. Eliglustat is an oral substrate reduction therapy approved in the European Union and the United States as a first-line treatment for adults with type 1 Gaucher disease who have compatible CY
Atrial fibrillation is the world's most common sustained cardiac arrhythmia and is associated with a significantly increased risk of stroke. The global burden of atrial fibrillation is rising, commensurate with the ageing population. Well-controlled vitamin K antagonist-based anticoagulation has been shown to reduce the risk of stroke secondary to atrial fibrillation by two-thirds. However, patien
Traditional farming landscapes in the temperate zone that have persisted for millennia can be exceptionally species-rich and are therefore key conservation targets. In contrast to Europe’s West, Eastern Europe harbours widespread traditional farming landscapes, but drastic socio-economic and political changes in the twentieth century are likely to have impacted these landscapes profoundly. We reco
The renewed growth in atmospheric methane (CH4) since 2007 after a decade of stabilization has drawn much attention to its causes and future trends. Wetlands are the single largest source of atmospheric CH4. Understanding wetland ecosystems and carbon dynamics is critical to the estimation of global CH4 and carbon budgets. After approximately 7 years of CH4 related research following the renewed g
Analogous to the death of developing neurones deprived of trophic factors, nerve injury in adult life could lead to nerve cell death by apoptosis. Here the occurrence of apoptotic mouse sciatic sensory neurones after injury was investigated by nick-labelling DNA breaks. A small proportion of the neurones reliably became apoptotic after injury in vivo. The response was strongly amplified when the n
Palsa mires, nutrient poor permafrost peatlands common in subarctic regions, store a significant amount of carbon (C) and it has been hypothesized their net ecosystem C balance (NECB) is sensitive to climate change. Over two years we measured the NECB for Stordalen palsa mire and found it to accumulate 46 g C m(-2) yr(-1). While Stordalen NECB is comparable to nutrient poor peatlands without perma
In this study we quantify the partitioning of recent assimilates to above- and below-ground carbon (C) pools in two subarctic mire ecosystems - wet minerotrophic and semiwet ombrotrophic mire - using in situ C-14 pulse-labelling. Ecosystem C partitioning to rhizomes, coarse roots, fine roots, dissolved organic carbon (DOC) and microbes were quantified twice during the growing season at three diffe
Regional vegetation-climate modelling studies have typically focused on boreal or temperate ecosystems in North America and Europe, almost completely overlooking tropical ecosystems. We present the first results of simulated regional vegetation-climate dynamics in Middle America as simulated by the model, LPJ-GUESS. The Kappa statistic indicated poor agreement, with a Kappa value of 0.301. When we
Many studies have found close relationships between accessibility and various socio-economic indicators. Yet, since accessibility tends to have differentiated effects, both socially and spatially, there is a need for a model which allows for a disaggregated analysis of accessibility. The model should be possible to use in areas where road network data is incomplete. In this paper such an accessibi
We have investigated the spatio-temporal carbon balance patterns resulting from forcing a dynamic global vegetation model with output from 18 climate models of the CMIP5 (Coupled Model Intercomparison Project Phase 5) ensemble. We found robust patterns in terms of an extra-tropical loss of carbon, except for a temperature induced shift in phenology, leading to an increased spring uptake of carbon.
Monte Carlo simulations and coarse-grained modelling have been used to analyze Histatin 5, which is an unstructured short cationic salivary peptide known to have anti-candidical properties. The calculated scattering functions have been compared with intensity curves and the distance distribution function P(r) obtained from SAXS, at both high and low salt concentrations. The aim is to achieve a mol
