Sökresultat

Abstract Treatment of chronic inflammatory arthritis has undergone major changes over the past years following introduction of targeted biological therapies. Tumour necrosis factor (TNF) blocking therapy has been the most important biological treatment of chronic arthritis to date. The overall objective of this thesis was to develop a new assessment method of efficacy of biological therapy in clin

Studies of the spin, parity and tensor couplings of the Higgs boson in the [Formula: see text], [Formula: see text] and [Formula: see text] decay processes at the LHC are presented. The investigations are based on [Formula: see text] of pp collision data collected by the ATLAS experiment at [Formula: see text] TeV and [Formula: see text] TeV. The Standard Model (SM) Higgs boson hypothesis, corresp

It is still unclear whether carbohydrate consumption is associated with cardiovascular disease (CVD) risk. Genetic susceptibility might modify the associations between dietary intakes and disease risk.

Objectives To ascertain if fetal head position on transabdominal ultrasound is associated with delivery by Cesarean section in nulliparous women with a prolonged first stage of labor. Methods This was a prospective observational study performed at Stavanger University Hospital, Norway, and Addenbrooke's Hospital, Cambridge, UK, between January 2012 and April 2013. Nulliparous pregnant women with a

The role of the world's boreal forest for our understanding of the climate system is indisputable. Due to the large area covered, the forest's biophysical (e.g. surface energy balance, albedo) and biogeochemical (e.g. bidirectional exchange of greenhouse gases or aerosol precursors) processes are known to affect today's climate, and will need to be accounted for in studies of climate feedbacks in

Introduction Given the safety issues of nonsteroidal anti-inflammatory drugs (NSAID) and the robustness of guidelines, making treatment choices in daily clinical practice is increasingly difficult. This study aimed systematically to analyse the opinions of a multidisciplinary European expert panel on the appropriateness of different NSAID, with or without the use of a proton pump inhibitor (PPI),

Projections of terrestrial carbon (C) dynamics must account for interannual variation in ecosystem C exchange associated with climate change, increasing atmospheric CO2 concentration, and species dynamics. We used a dynamic ecosystem model to (i) project the potential dynamics of C in New England forests under nine climate change scenarios (CCSs) for the 21st century and (ii) examine the sensitivi

Despite numerous challenges, since its independence, Uzbekistan, with the exception of the May 2005 Andijan events, has enjoyed extraordinary political stability and not recorded any considerable cases of interethnic or interfaith conflict, regime change or civil war, whereas neighboring Kyrgyzstan, labeled an “island of democracy” by the Western world, has experienced numerous conflicts and chaos

High and low pollen deposition years in the period 1998-2010 were recorded for ten forest-forming trees in Roztocze (SE Poland) using Tauber-style traps. The coincidence of very high/low pollen deposition years recorded in Tauber traps and aerobiological data obtained by volumetric samplers shows that these phenomena occur simultaneously in different places across vast areas of a tree's distributi

Here we present results from a field experiment in an Arctic wetland situated in Zackenberg, NE Greenland. During one growing season we investigated how dominance of the sedge Eriophorum scheuchzeri affected the below-ground concentrations of low molecular weight carbon compounds (LMWOC) and the fluxes of CO2 and CH4 in comparison to dominance of other sedges (Carex stans and Dupontia psilosantha)

The relation between delta O-18 of precipitation and temperature has been used in numerous studies to reconstruct past temperatures at ice core sites in Greenland and Antarctica. During the past two decades, it has become clear that the slope between delta O-18 and temperature varies in both space and time. Here, we use a general circulation model driven by changes in orbital parameters to investi

Detailed stratigraphic analyses of sediments deposited in Lake Botjarnen, a small boreal forest lake in the shield terrain of central Sweden, clearly reflect progressively increasing human impact on terrestrial and aquatic ecosystems following settlement and establishment of an iron industry in the 17th century. Rising frequencies of pollen and spores from light-demanding plants provide evidence o

WHAT THIS STUDY ADDS Previous comparisons between open and endovascular repair of popliteal aneurysms have focused on asymptomatic patients, and have short follow up. This study is strengthened by the fact that it is contemporary, population based, without any selection bias, reporting on all kinds of presentations, and has approximately 90% 1 year follow up data. It shows that endovascular repair

We report the measurement of cumulants (C-n,n = 1, ..., 4) of the net-charge distributions measured within pseudorapidity (vertical bar eta vertical bar < 0.35) in Au + Au collisions at root s(NN) = 7.7-200 GeV with the PHENIX experiment at the Relativistic Heavy Ion Collider. The ratios of cumulants (e.g., C-1/C-2, C-3/C-1) of the net-charge distributions, which can be related to volume independe

Understanding spatial and temporal variability in the distribution of seabirds is fundamental for the conservation and management of marine ecosystems. In the absence of large-scale systematic survey data, the application of standard habitat modelling techniques to predict the at-sea distributions of seabirds at large spatial scales has been limited. In this study, we examine the utility of relati

Popular Abstract in Swedish En fråga om liv och hälsa Livstillfredsställelse, personlighet och mortalitet i två äldre populationer Enligt en rapport från FN (2001) kan vi under de kommande 50 åren förvänta oss att andelen äldre över 60 år kommer att fördubblas. Ny och förbättrad teknik, medicinsk kunskap och behandling har utvecklats, vilket innebär att vi i dag överlever i större utsträckning dThe aims of the present thesis were to explore and describe elderly people’s morbidity and experience of symptoms in relation to life satisfaction, personality and mortality. (I, II and III) To learn from the individuals who have high life satisfaction in spite of the fact that they have concurrent medical diagnoses and conditions. (I and III) To reason how positive factors and strengths might hel