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The effects of five different calcium antagonists (diltiazem, felodipine, nifedipine, nimodipine, and verapamil) on cat skeletal muscle resistance and capacitance vessels were studied in a whole organ preparation. These calcium antagonists seemed to have the similar qualitative effects on these vascular functions. Calcium antagonists were found to be potent inhibitors of myogenic vascular reactivi
The concept of acoustic comfort is hardly defined and used to refer to conditions of low noise levels or annoyance based on standardized descriptors. Airborne and impact sound measurements are used to rate acoustic comfort in dwellings, but they often do not express human perception of noise or comfort. If the descriptors are statistically associated with self-reported responses, they can be used
Thromboembolism frequently occurs during acute lymphoblastic leukemia (ALL) therapy. We prospectively registered thromboembolic events during the treatment of 1772 consecutive Nordic/Baltic patients with ALL aged 1 to 45 years who were treated according to the Nordic Society of Pediatric Hematology and Oncology ALL2008 protocol (July 2008-April 2017). The 2.5-year cumulative incidence of thromboem
Based on extensive ethnographic fieldwork in Uzbekistan, this article looks at the way official state narratives are challenged by silent, unorganised, often unaware gestures of resistance at the bottom of a society. Footing on a framework suggested by Scott’s definition of infrapolitics (2012), we propose to incorporate informal practices in a definition of informality that is more inclusive and
Background When the lectinlike oxidized low-density lipoprotein (ox LDL) receptor-1 ( LOX -1), a scavenger receptor for ox LDL , binds ox LDL , processes leading to endothelial dysfunction and inflammation are promoted. We aimed to study release mechanisms of LOX -1 and how circulating levels of soluble LOX -1 ( sLOX -1) relate to plaque inflammation and future risk for ischemic stroke. Methods an
The present paper investigates the fluid flow and heat transfer behaviors of jet impingement in cross-flow modified by a vortex generator pair (VGP). The velocity of the jet is kept at 12 m/s and that of the cross-flow is varied between 5 m/s and 8 m/s. The spacing between the jet and target surface is 4 times the jet diameter. Particle Image Velocimetry (PIV) and Liquid Crystal Thermography (LCT)
Background: Inadequate stores or intakes of essential minerals in pregnancy, or too high exposure to both toxic and essential elements, can have adverse effects on mother and child. The main aims of this study were to 1) describe the concentrations and patterns of essential and toxic elements measured in maternal whole blood during pregnancy; 2) identify dietary, lifestyle and sociodemographic det
Botulinum neurotoxins (BoNTs) are a family of highly dangerous bacterial toxins, with seven major serotypes (BoNT/A-G). Members of BoNTs, BoNT/A1 and BoNT/B1, have been utilized to treat an increasing number of medical conditions. The clinical trials are ongoing for BoNT/A2, another subtype of BoNT/A, which showed promising therapeutic properties. Both BoNT/A1 and BoNT/A2 utilize three isoforms of
Reciprocal ST depression, PR depression in the chest leads and terminal QRS distortion may improve detection of true STEMI. Convex STE is more common in ischemic than in non-ischemic patients, but the majority of STEMI patients present without convex STE.
Six-membered cyclic carbonates with hydroxyl and methoxycarbonyloxy functional groups were prepared by transesterification of trimethylolpropane (TMP) with dimethylcarbonate (DMC) by solvent-free lipase-mediated flow reaction followed by thermal cyclization. The flow reaction efficiency was evaluated using different configurations of reactor consisting of packed beds of Novozym®435 (immobilized Ca
This chapter explores the initial development of VOT in three Swedish-speaking learners of French (age of onset: 3;0-3;5). Swedish uses long lag and short lag/lead to differentiate voiceless and voiced stops word-initially (Helgasson & Ringen 2008; Sundberg & Lacerda 1999). In French this distinction is made using short lag and lead (Kessinger och Blumstein 1997). Through a memory game wor
Mitochondria from different regions of the brain were prepared, and the activation of the mitochondrial permeability transition (MPT) by calcium was investigated by monitoring the associated mitochondrial swelling. In general, the properties of the MPT in brain mitochondria were found to be qualitatively similar to those observed in liver and heart mitochondria. Thus, swelling was inhibited by ade
Hypoxic pulmonary vasoconstriction (HPV) serves to optimize ventilation-perfusion matching in focal hypoxia and thereby enhances pulmonary gas exchange. During global hypoxia, however, HPV induces general pulmonary vasoconstriction, which may lead to pulmonary hypertension (PH), impaired exercise capacity, right-heart failure and pulmonary oedema at high altitude. In chronic hypoxia, generalized H
The geo-political transition in 1989-91 had long term consequences for the European integration process. The integration and regionalisation processes following the transition resulted in a transformation of territorial borders in and around the region; the functions of the borders changed. Mobility is vital for these processes. This paper is based on a longitudinal study of the development of air
In this paper I discuss the work of two French authors who advocate a "scientific" exegesis of sacred scriptures: physician Maurice Bucaille (1922-1998) and religious leader Claude Vorilhon (alias Raël, b. 1946). Bucaille argues that the Qur'an's divine origin is demonstrated by its accuracy about natural phenomena and "scientific facts," whereas the Bible does not stand up to "scientific" examina
It has been suggested that calcium changes the set point of the pituitary thyroid feedback. It is not known, however, if small and slow changes of calcium and/or parathyroid hormone (PTH) within the physiological range influence the serum levels of thyrotropin (TSH) and thyroid hormones in healthy subjects or patients with primary hyperparathyroidism (pHPT). Nine healthy subjects and nine patients
In this paper, we explore consumers’ in-store experiences and their components, from both a consumer and retailer perspective. This is a replication of a study we performed in 2006 and thus we also examine how the role of the physical store has changed over the last decade. We use the Critical Incident Technique (CIT) to improve our understanding of consumers’ in-store experiences. Moreover, we co
