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The mutation status of the immunoglobulin heavy chain variable regions (IgVH) has been found to be a good prognostic indicator for B-cell chronic lymphocytic leukemia (CLL) because unmutated VH genes are associated with rapid disease progression and shorter survival time. To study the differences in gene expression between the Ig-unmutated and Ig-mutated CLL subtypes, we performed gene expression
Functional imaging is becoming increasingly important for the detection of neurodegenerative disorders. Perfusion MRI with arterial spin labeling (ASL) has been reported to provide promising diagnostic possibilities but is not yet widely used in routine clinical work. The aim of this study was to compare, in a clinical setting, the visual assessment of subtracted ASL CBF maps with and without addi
The role of quantitative risk analysis as a foundation for decision making, regarding hazardous activities and establishments, has gained increased importance during the last decades. When performing a quantitative risk analysis, a wide range of uncertainties will inevitably be introduced during the process. The impact of these uncertainties must somehow be addressed if the analysis is to serve as
Since listeners usually look at the speaker's face, gestural information has to be absorbed through peripheral visual perception. In the literature, it has been suggested that listeners look at gestures under certain circumstances: 1) when the articulation of the gesture is peripheral; 2) when the speech channel is insufficient for comprehension; and 3) when the speaker him- or herself indicates t
This paper focuses on the grammatical expression or ‘packaging’ of modality in Japanese. I consider two aspects: (1) the grammatical encoding of epistemic, deontic, and evidential notions with English as a point of comparison, and (2) the co-encoding of modality and subjectivity. As for the former aspect, the comparison between Japanese and English exemplifies how languages can take different stra
Abstract> Objectives. Diagnostics of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) are complex, and based on the 2010 Task Force document including different diagnostic modalities. However, recommendations for clinical management and follow-up of patients with ARVC and their relatives are sparse. This paper aims to give a practical overview of management strategies, risk str
Shallow lakes have great ecological and recreational values. They are also largely affected by humans, mainly through eutrophication, and great efforts are therefore being put into the understanding of these ecosystems. The knowledge is however not complete, and more research is needed to manage these lakes in a sustainable way. The physical characteristics that are special for shallow lakes compa
A model is presented which gives a quantitative picture of the distribution of the photosynthetic components in the thylakoid membrane of higher plants. The model is based on fragmentation and separation analysis together with microscopy. A salient feature of the model is that over 80 per cent of the pigments are located in the grana where the two photosystems 1 and 2 produce oxygen, NADPH and ATP
The paper concerns the furniture industry’s increased interest in opportunities and challenges to respond to demographic shifts and to meet future senior markets. A central issue discussed is how a user-centred approach in a collaborative design research project benefited the industrial partners. The paper focuses on the perspectives of the participating furniture manufacturers. The most involved
Dynamics of spontaneous decay and corresponding emission spectrum areexactly treated for a system of two identical two-level atoms in 1D.Just a one-dimensional case is considered in order to maximally extractan information on mutual influence of spatially remote atoms through theradiation field. As a result, an effect is revealed and considered indetail that there exist stable (metastable) entangl
We identified several compounds, by gas chromatographic–electroantennographic detection (GC–EAD), that were antennally active in the bark beetle Ips typographus and also abundant in beetle-attacked spruce trees. One of them, 1,8-cineole (Ci), strongly inhibited the attraction to pheromone in the field. Single-sensillum recordings (SSRs) previously showed olfactory receptor neurons (ORNs) on I. typ
Katekeser är en genre som vanligtvis förknippas med lutheransk religionsundervisning, och inte revolutioner. Dess form, att ställa en antal givna frågor och ge ett definitivt svar för varje fråga synes lämna föga utrymme för självständigt och kritiskt tänkande. Frågandet som teknik är en retorik; syftet är att styra läsarens tänkande i avsedd riktning. Inpräntande av normer, inte radikala reflekti
