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Aim: To assess Ig20Gly tolerability in pediatric patients with primary immunodeficiencies. Patients & methods: Infusion parameters and tolerability were analyzed in pediatric patients (aged 2-5 years [n = 6], 6-11 years [n = 22] and 12-17 years [n = 22]) receiving Ig20Gly in two Phase II/III trials. Results: Of 2624 Ig20Gly infusions, >99% did not require any rate reduction, interruption or di
Large herbivores can control plant community composition and, under certain conditions, even induce vegetation shifts to alternative ecosystem states. As different plant assemblages maintain contrasting carbon (C) cycling patterns, herbivores have the potential to alter C sequestration at regional scales. Their influence is of particular interest in the Arctic tundra, where a large share of the wo
Climate change is not only changing the Arctic environment and ecosystems: it is also opening up the idea of the region as a last frontier to be explored. Recent representations of the future for the Arctic have become closely associated with various business-friendly opportunities as the land and sea ice is melting: They often represent so-called win-win solutions to climate change, also for Arct
In this article, we discuss Swedish crisis management from the perspective that public administration has evolved from a government steering structure to a governance structure. The power to govern crisis policy has been partly transferred from "government" to autonomous policy networks, which may include both public and private actors. Geographic area responsibility is assigned to the Government
In times of climate change political goals concern a reduction in total energy consumption and to use energy more efficiently. To achieve this, users need to transform their behaviour and start reflecting on their energy use. This paper discusses three different methods for visualising energy use, namely information tools, keeping time-diaries and using the 'Power-Aware Cord'. Each method has its
Studies on survival between familial and sporadic cancers have been inconclusive and only recent data on a limited number of cancers are available on the concordance of survival between family members. In this review, we address these questions by evaluating the published and unpublished data from the nation-wide Swedish Family-Cancer Database and a total of 13 cancer sites were assessed. Using sp
Swedish dissertations are public, followed by closedassessment committee meetings that only report pass-failvotes. 166 external examiners from 72 doctoral dissertationswere therefore anonymously surveyed for their views on passfail norms, scientific standard of theses and candidates and theacademic independence of the assessed candidate. They werealso asked to relate their assessment to the nation
Water resources are under increasing pressure, and there are tensions between increasing demand and the natural limits to potable water supply. Authorities must find solutions that fulfil societal demands without compromising environmental integrity. As one way to counteract water deficits, desalination has evolved as an attractive solution. This technology is contested and associated with a varie
In order to improve the efficiency of inspections, quantitative data on defect content have to be the basis for decisions in the inspection process. An experience-based capture-recapture method is proposed, which overcomes some problems with the basic pre-requisites of the original method. A C-code inspection experiment is conducted to evaluate the enhanced method and its applicability to software
Because of the scale of global displacement, in particular from Syria, the European Union has stressed the need to work on an effective asylum and immigration policy through more robust forms of cooperation internally, between Member States, and externally, with third countries. This contribution investigates the extent to which the EU rules for distributing asylum responsibilities genuinely addre
Background: Many translational MR biomarkers derive from measurements of the water proton longitudinal relaxation rate R 1 , but evidence for between-site reproducibility of R
Depending on the proticity of the solvent, two different salts may be crystallized from the combination of solutions of guanidinium chloride, C(NH2)3Cl, and the acidic hydrate of molybdenum dichloride, [(Mo6Cl8)Cl6](H20 O9). From aprotic solvents such as dimethyl sulfoxide (DMSO) or formamide (FA), compound I, [(Mo6Cl8) Cl6]Cl6(C(NH2)3)8, crystallizes, while from protic solvents such as ethanol or
In light of the changing circumstances for teaching, teachers’ views on organizational communication processes were explored. Empirically, this paper is based on five semi-structured focus groups, each interviewed on two occasions. In total, 44 primary and lower secondary-school teachers working in one municipality in Sweden participated. The interviews were framed by a pre-survey concerning demog
BackgroundParkinson's disease (PD) management comprises of drug treatments, surgery, and physical activity/occupational therapies to relieve PD's symptoms. The aim of this study is twofold; first, to appraise recent economic evaluation studies on PD management in order to update the existing knowledge; and second, to facilitate decision making on PD management by assessing the cost‐effectiveness o
In education programs with an artistic ground, i.e. where the student is supposed to develop an artistic skill, the overall objective is to provide the fundament for a practitioner to become a well functioning individual in a specific artistic community. This artistic community of practice plays – directly through professionally active teachers, and indirectly through teachers with a good understa
Some recent studies showed that in vitro bioassays based on fish or human estrogen receptor (ER) activation may have distinct responses to environmental samples, highlighting the need to better understand bioassay-specific ER response to environmental mixtures. For this purpose, we investigated a 12-compound mixture in two mixture ratios (M1 and M2) on zebrafish (zf) liver cells stably expressing
