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The recruitment of antigen-specific T lymphocytes to the intestinal mucosa is central to the development of an effective mucosal immune response, yet the mechanism by which this process occurs remains to be fully defined. Here we show that the CC chemokine receptor 9 (CCR9) is selectively and functionally expressed on murine alpha(E)beta(7)(+) naive CD8alphabeta(+) lymphocytes and a subset of rece
The CD40-CD40L interaction plays a critical role in both humoral and cellular immune responses and interfering antibodies have been suggested as an effective approach for the treatment of lymphomas and autoimmune diseases. In this study we have profiled a panel of mouse antihuman CD40 monoclonal antibodies (MoAbs), regarding their CD40 binding affinity and epitope-specificity relative to the CD40L
Popular Abstract in Swedish I denna avhandling studeras begravningsentreprenörernas arbete. Materialet är i första hand inhämtat genom intervjuer och observationer på begravningsbyråer som tillhör Sveriges Begravningsbyråers Förbund. Begravningsentreprenörer upplever att det finns en negativ bild av yrket, som är kopplad till hanteringen av avlidna. Samtidigt efterfrågas begravningsentreprenörernThis dissertation has a dual purpose. Firstly to describe what funeral directors do and how they experience their work. Secondly to see if, and in that case how, funeral directors influence rites around the deceased, both official as well as more private rites. The study is based on text analysis, interviews with 32 funeral directors and field studies on four funeral parlours. Only funeral directo
To examine the association between perceived environmental barriers to and facilitators for outdoor mobility with life-space among older people.
In this paper, we study the problem of drawing a given planar graph such that vertices are at pre-specified points and the entire drawing is inside a given polygon. We give a method that shows that for an $n$-vertex graph and a $k$-sided polygon, $\Theta(kn^2)$ bends are always sufficient. We also give an example of a graph where $\Theta(kn^2)$ bends is necessary for such a drawing.
Chronic degenerative mitral regurgitation (MR) with left atrial (LA) enlargement is predictive of adverse cardiovascular events including stroke, atrial fibrillation (AF), and impaired survival. Mitral valve surgery (MVS) initiates left atrial reverse remodeling (LARR) characterized by LA volume reduction and improved function. The aim of this study was to evaluate the effects of LARR on clinical
Several ceramic biomaterials have been suggested as promising alternatives to autologous bone to replace or restore bone after trauma or disease. The osteoinductive potential of most scaffolds is often rather low by themselves and for this reason growth factors or drugs have been supplemented to these synthetic materials. Although some growth factors show good osteoinductive potential their drawba
The main aim of this study was to evaluate an occupational therapy based intervention aimed at increasing the accessibility to buildings with public facilities in a Swedish town centre, which targeted physical environmental barriers. The intervention was occupational therapy advice based on the environmental assessments of each facility, given to the facility owners in order to ease the removal of
The article investigates the relationship between Sweden and the Ottoman Empire during the eighteenth century with a focus on the travelogue of Jacob Björnståhl.
This paper explores how the Engineering Design process might balance conflicting constraints of technical product design and the social demands of users. Building on a generic 2D map for innovation in design from the author’s previous work, a prototype 3D Diamond Model is presented to help structure conversations between Designers and Users – or indeed any other group with apparently opposing aims
Delays and cost overruns are frequent problems in the construction industries of both developed and developing countries. Studies aimed at identifying the causes are often undertaken with just a broad appreciation of the construction process and frequently do not deal with multicultural issues when considering the reasons for overruns. The paper critically reviews existing attempts to uncover the
