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Popular Abstract in Danish Med udgangspunkt i et kompetenceudviklingsprojekt for lærere i en svensk kommune adresserer denne afhandling de stigende krav til forandring og innovation, der karakteriserer den offentlige sektor generelt. Ved at følge kompetenceudviklingsprojektet gennem en fire-årig periode sættes projektet i en kontekst af innovation, globalisering og forandring. Forfatteren argumentThis dissertation critically analyses the discourse on educational change. By placing educational change in the context of globalisation and innovation the author argues that the current discourse on educational change is un-nuanced and omits the important perspectives on change. The author has analysed an educational district in Sweden and one of its projects on competence development, named 'Str

The immune system is remarkable in many ways. It exerts immunity to defend us from foreign pathogens, while it is also responsible for maintaining tolerance to avoid autoimmune diseases and allergy. This thesis includes three separate papers concerning both tolerance and immunity. In paper I we report that repeated antigen stimulation results in an increased proportion of Foxp3+ cells in the CD4+

Objective: To examine the contents of the Mayo-Portland Adaptability Inventory (MPAI-4) by mapping it to the International Classification of Functioning, Disability and Health (ICF). Methods: Each of the 30 scoreable items in the MPAI-4 was mapped to the most precise ICF categories. Results: All 30 items could be mapped to components and categories in the ICF. A total of 88 meaningful concepts wer

In the last decades, the growing competitiveness of the market has continuously driven the forming companies to highly optimize their products regarding offered performance at minimum cost. In order to achieve better products, studies where conducted with different material models when simulating the forming process of titanium. The material is often used in heat exchanger applications. Titanium h

We propose a simple, general and computationally efficient algorithm for maximum likelihood estima- tion (MLE) of parameters in diffusion and jump-diffusion processes. This is conducted within a Monte Carlo EM-algorithm, where the smoothing distribution is computed using resampling. The results are encouraging as we can approximate the MLE well for the models studied when using simulated data. We

Popular Abstract in Swedish Huvud- hals cancer Studier kring betydelsen av kärltäthet, svar på strålbehandling och tumörmetabolism, undersökt med positron emissions tomografi ( PET) Bakgrund Cancer i huvud-hals området är ovanligt i Sverige och utgör c:a 2,5% av alla nya cancerfall (40 000) per år. Beteckningen är ett samlingsnamn för tumörer med sinsemellan skilda egenskaper, uppkomna från i förTreatment options of head and neck squamous cell carcinoma (HNSCC) usually include combinations of radiotherapy and surgery, and in some cases addition of chemotherapy. In locally advanced cases cure rates are low. Current prognostic factors cannot foresee the outcome for the individual patient. There is consequently a need for reliable prognostic and predictive factors. Through identification of

The Swedish Air Navigation Service Provider in cooperation with the University of Lund aims at developing a model for supporting continuous improvements and learning focusing on safety in air traffic control. This paper focuses on relationships between the safety culture and the psychosocial working environment. These areas were studied using questionnaires at the two main air traffic control cent

In the West, everybody is now talking about the economic and financial crisis. The term ‘’crisis” has become a buzzword within both academic and policy communities. There is an enormous upsurge of scholarly interest in the effects of this crisis on public administration systems, and the role that public administration plays in these processes. The underlying belief is that the public administratio

Popular Abstract in Swedish Digital bildteknik dominerar snart all bildhantering inom alla delar av samhället. Målsättningen med denna avhandling var att utveckla en undersökningsmetod för mätning av knäleden i belastat läge med hjälp av digital bildplatteteknik. Vad är bildplatteteknik? Traditionellt har röntgenbilder framställts med hjälp av fotografisk film. De framkallade bilderna har sedan The overall aim of this study was to develop and evaluate a measurement system for computed radiography (CR) and Picture Archiving and Communication Systems (PACS), permitting measurements of long distances and angles in and between related images. The developed measurement system, which was based on the QUESTOR Precision Radiography (QPR) system, was applied to the weight-bearing knee with specia

We present an estimate for the convergence rate of the Dirichlet-Neumann iteration for the discretized unsteady transmission problem. Specifically, we consider the coupling of two heat equations on two identical squared domains. The Laplacian is discretized by second order central finite differences and the implicit Euler method is used for the time discretization. For the semidiscrete case, Hensh

Popular Abstract in Swedish I »operatörens blick« beskrivs ett projekt där möjligheter för IT-stöd i erfarenhetsöverföring undersökts inom ett område där konfrontationen mellan datorisering och yrkeskunnande är särskilt tydlig - operatörsarbete i processindustrin. Driftsstörningar av olika omfattning är ett kontinuerligt inslag i operatörsarbetet och snabba förändringar i risknivå är en central deStudies in process control automation show that manual control skills are important in handling situations where the automatic control system fails. The fact that these skills are particularly difficult to maintain and develop in automated production environments is usually described as one of the ironies of automation. This work explores new roles for computer support in developing and maintainin

Knockout of caspase-8, a cysteine protease that participates in the signaling for cell death by receptors of the TNF/nerve growth factor family, is lethal to mice in utero. To explore tissue-specific roles of this enzyme, we established its conditional knockout using the Cre/loxP recombination system. Consistent with its role in cell death induction, deletion of caspase-8 in hepatocytes protected

In order to identify cellular factors that regulate human papillomavirus type 16 (HPV16) gene expression, cervical cancer cells permissive for HPV16 late gene expression were identified and characterized. These cells either contained a novel spliced variant of the L1 mRNAs that bypassed the suppressed HPV16 late, 5'-splice site SD3632, produced elevated levels of RNA-binding proteins SRSF1 (ASF/SF

This paper reports on a joint numerical and experimental investigation of the release of potassium from biomass during gasification process. In this work, laser-induced breakdown spectroscopy (LIBS) was adopted to measure quantitatively the concentration of potassium from gasifying biomass. The effect of temperature on the potassium release is investigated in hot gas mixture of CO2, H2O with diffe

The use of induction therapy may reduce the risk of acute rejection after heart transplantation. This study assessed the association between basiliximab (BAS) vs anti-thymocyte globulin (ATG) induction and long-term survival after heart transplantation.

Various healthcare interventions have been launched targeting the growing population of older people. The objective of this study was to investigate the of a case management intervention for frail old people (aged 65+ years) effects on healthcare utilization.

Objectives: The aim of this study was to estimate the cost-effectiveness of rituximab in patients not responding adequately to the first tumor necrosis factor (TNF) inhibitor using a model constructed to predict resource consumption and health outcomes in a population-based registry of biological treatments in Southern Sweden (SSATG). Methods: The model was developed as a discrete event simulation

The aim of this study was to investigate patients’ experiences of living with peripheral arterial disease (PAD) and the influence on activities of daily living. Twenty-four patients with various degrees of PAD were interviewed. The transcribed texts were analysed using manifest and latent content analysis. Living with PAD meant carrying a hard-to-bear physical, social and emotional burden, and str